HIPK3 (homeodomain interacting protein kinase 3)

Identity

Other names	DYRK6
	FIST3
	PKY
	YAK1
Hugo	HIPK3
Location	11p13
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
Hugo	HIPK3
GDB	HIPK3
Entrez_Gene	HIPK3  10114  homeodomain interacting protein kinase 3
	Cards
GeneCards	HIPK3
Ensembl	HIPK3 [Search_View]   ENSG00000110422 [Gene_View]
Genatlas	HIPK3
GeneLynx	HIPK3
eGenome	HIPK3
euGene	10114
	Genomic and cartography
GoldenPath	HIPK3  -  11p13   chr11:33235744-33332515 +  11p13   [Description]    (hg18-March_2006)
Ensembl	HIPK3 - 11p13 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	HIPK3
	Gene and transcription
Genbank	AA456456 [ ENTREZ ]
Genbank	AF004849 [ ENTREZ ]
Genbank	AF305239 [ ENTREZ ]
Genbank	AK293009 [ ENTREZ ]
Genbank	AL597397 [ ENTREZ ]
RefSeq	NM_001048200 [ SRS ]    NM_001048200 [ ENTREZ ]
RefSeq	NM_005734 [ SRS ]    NM_005734 [ ENTREZ ]
RefSeq	AC_000054 [ SRS ]    AC_000054 [ ENTREZ ]
RefSeq	NC_000011 [ SRS ]    NC_000011 [ ENTREZ ]
RefSeq	NT_009237 [ SRS ]    NT_009237 [ ENTREZ ]
RefSeq	NW_925006 [ SRS ]    NW_925006 [ ENTREZ ]
AceView	HIPK3 AceView - NCBI
Unigene	Hs.201918 [ SRS ]    Hs.201918 [ NCBI ]     HS201918 [ spliceNest ]
Fast-db	4708 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q9H422 [ SRS]    Q9H422 [ EXPASY ]     Q9H422 [ INTERPRO ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00108 PROTEIN_KINASE_ST [ SRS ]    PS00108 PROTEIN_KINASE_ST [ Expasy ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR008271 Ser_thr_pkin_AS [ SRS ]    IPR008271 Ser_thr_pkin_AS [ EBI ]
Interpro	IPR002290 Ser_thr_pkinase [ SRS ]    IPR002290 Ser_thr_pkinase [ EBI ]
CluSTr	Q9H422
Pfam	PF00069 Pkinase [ SRS ]    PF00069 Pkinase [ Sanger ]    pfam00069 [ NCBI-CDD ]
Smart	SM00220 S_TKc [EMBL]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	Q9H422 HIPK3_HUMAN [ Domain structure ]   Q9H422 HIPK3_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	Q9H422
HPRD	05111
	Protein Interaction databases
DIP	Q9H422
IntAct	Q9H422
	Polymorphism : SNP, mutations, diseases
OMIM	604424    [ map ]
GENECLINICS	604424
SNP	HIPK3 [dbSNP-NCBI]
SNP	NM_001048200 [SNP-NCI]
SNP	NM_005734 [SNP-NCI]
SNP	HIPK3 [GeneSNPs - Utah]  HIPK3] [HGBASE - SRS]
HAPMAP	HIPK3 [HAPMAP]
COSMIC	HIPK3 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	HIPK3
	General knowledge
Family Browser	HIPK3 [UCSC Family Browser]
SOURCE	NM_001048200
SOURCE	NM_005734
SMD	Hs.201918
SAGE	Hs.201918
Enzyme	2.7.11.1 [ Enzyme-SRS ]   2.7.11.1 [ Brenda-SRS ]   2.7.11.1 [ KEGG ]   2.7.11.1 [ WIT ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	protein serine/threonine kinase activity [Amigo]  protein serine/threonine kinase activity
GO	ATP binding [Amigo]  ATP binding
GO	nucleus [Amigo]  nucleus
GO	cytoplasm [Amigo]  cytoplasm
GO	transcription [Amigo]  transcription
GO	regulation of transcription, DNA-dependent [Amigo]  regulation of transcription, DNA-dependent
GO	apoptosis [Amigo]  apoptosis
GO	anti-apoptosis [Amigo]  anti-apoptosis
GO	transferase activity [Amigo]  transferase activity
GO	peptidyl-serine phosphorylation [Amigo]  peptidyl-serine phosphorylation
GO	peptidyl-threonine phosphorylation [Amigo]  peptidyl-threonine phosphorylation
GO	negative regulation of JNK activity [Amigo]  negative regulation of JNK activity
PubGene	HIPK3
TreeFam	HIPK3
CTD	10114 [Comparative Genomics Database]
	Other databases
	Probes
Probe	HIPK3 Related clones (RZPD - Berlin)
	PubMed
PubMed	14 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Thu May 22 20:10:20 2008