Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

HIST1H1A (histone cluster 1 H1 family member a)

Identity

Alias_namesH1F1
H1 histone family, member 1
histone 1, H1a
histone cluster 1, H1a
Alias_symbol (synonym)H1.1
H1a
Other aliasH1A
HIST1
HGNC (Hugo) HIST1H1A
LocusID (NCBI) 3024
Atlas_Id 124
Location 6p22.2  [Link to chromosome band 6p22]
Location_base_pair Starts at 26017032 and ends at 26017812 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  3q27 rearrangements (BCL6) in non Hodgkin lymphoma::t(3;Var)(q27;Var) in non Hodgkin lymphoma
t(3;14)(q27;q32) IGH/BCL6::t(2;3)(p12;q27) IGK/BCL6::t(3;22)(q27;q11) IGL/BCL6


External links

Nomenclature
HGNC (Hugo)HIST1H1A   4715
Cards
Entrez_Gene (NCBI)HIST1H1A  3024  histone cluster 1 H1 family member a
AliasesH1.1; H1A; H1F1; HIST1
GeneCards (Weizmann)HIST1H1A
Ensembl hg19 (Hinxton)ENSG00000124610 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124610 [Gene_View]  ENSG00000124610 [Sequence]  chr6:26017032-26017812 [Contig_View]  HIST1H1A [Vega]
ICGC DataPortalENSG00000124610
TCGA cBioPortalHIST1H1A
AceView (NCBI)HIST1H1A
Genatlas (Paris)HIST1H1A
WikiGenes3024
SOURCE (Princeton)HIST1H1A
Genetics Home Reference (NIH)HIST1H1A
Genomic and cartography
GoldenPath hg38 (UCSC)HIST1H1A  -     chr6:26017032-26017812 -  6p22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HIST1H1A  -     6p22.2   [Description]    (hg19-Feb_2009)
EnsemblHIST1H1A - 6p22.2 [CytoView hg19]  HIST1H1A - 6p22.2 [CytoView hg38]
Mapping of homologs : NCBIHIST1H1A [Mapview hg19]  HIST1H1A [Mapview hg38]
OMIM142709   
Gene and transcription
Genbank (Entrez)BC069492 BC101593 BC112140
RefSeq transcript (Entrez)NM_005325
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HIST1H1A
Cluster EST : UnigeneHs.150206 [ NCBI ]
CGAP (NCI)Hs.150206
Alternative Splicing GalleryENSG00000124610
Gene ExpressionHIST1H1A [ NCBI-GEO ]   HIST1H1A [ EBI - ARRAY_EXPRESS ]   HIST1H1A [ SEEK ]   HIST1H1A [ MEM ]
Gene Expression Viewer (FireBrowse)HIST1H1A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3024
GTEX Portal (Tissue expression)HIST1H1A
Human Protein AtlasENSG00000124610-HIST1H1A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ02539   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ02539  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ02539
Splice isoforms : SwissVarQ02539
PhosPhoSitePlusQ02539
Domaine pattern : Prosite (Expaxy)H15 (PS51504)   
Domains : Interpro (EBI)Histone_H1/H5_H15    Histone_H5    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)Linker_histone (PF00538)   
Domain families : Pfam (NCBI)pfam00538   
Domain families : Smart (EMBL)H15 (SM00526)  
Conserved Domain (NCBI)HIST1H1A
DMDM Disease mutations3024
Blocks (Seattle)HIST1H1A
SuperfamilyQ02539
Human Protein Atlas [tissue]ENSG00000124610-HIST1H1A [tissue]
Peptide AtlasQ02539
HPRD00820
IPIIPI00217469   
Protein Interaction databases
DIP (DOE-UCLA)Q02539
IntAct (EBI)Q02539
FunCoupENSG00000124610
BioGRIDHIST1H1A
STRING (EMBL)HIST1H1A
ZODIACHIST1H1A
Ontologies - Pathways
QuickGOQ02539
Ontology : AmiGOnucleosome  nuclear chromatin  protein binding  nuclear euchromatin  nucleosome assembly  spermatogenesis  heparin binding  cell surface  chromatin DNA binding  vesicle  positive regulation of receptor-mediated endocytosis  
Ontology : EGO-EBInucleosome  nuclear chromatin  protein binding  nuclear euchromatin  nucleosome assembly  spermatogenesis  heparin binding  cell surface  chromatin DNA binding  vesicle  positive regulation of receptor-mediated endocytosis  
NDEx NetworkHIST1H1A
Atlas of Cancer Signalling NetworkHIST1H1A
Wikipedia pathwaysHIST1H1A
Orthology - Evolution
OrthoDB3024
GeneTree (enSembl)ENSG00000124610
Phylogenetic Trees/Animal Genes : TreeFamHIST1H1A
HOVERGENQ02539
HOGENOMQ02539
Homologs : HomoloGeneHIST1H1A
Homology/Alignments : Family Browser (UCSC)HIST1H1A
Gene fusions - Rearrangements
Fusion : QuiverHIST1H1A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIST1H1A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIST1H1A
dbVarHIST1H1A
ClinVarHIST1H1A
1000_GenomesHIST1H1A 
Exome Variant ServerHIST1H1A
ExAC (Exome Aggregation Consortium)ENSG00000124610
GNOMAD BrowserENSG00000124610
Genetic variants : HAPMAP3024
Genomic Variants (DGV)HIST1H1A [DGVbeta]
DECIPHERHIST1H1A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHIST1H1A 
Mutations
ICGC Data PortalHIST1H1A 
TCGA Data PortalHIST1H1A 
Broad Tumor PortalHIST1H1A
OASIS PortalHIST1H1A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHIST1H1A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHIST1H1A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIST1H1A
DgiDB (Drug Gene Interaction Database)HIST1H1A
DoCM (Curated mutations)HIST1H1A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIST1H1A (select a term)
intoGenHIST1H1A
Cancer3DHIST1H1A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM142709   
Orphanet
DisGeNETHIST1H1A
MedgenHIST1H1A
Genetic Testing Registry HIST1H1A
NextProtQ02539 [Medical]
TSGene3024
GENETestsHIST1H1A
Target ValidationHIST1H1A
Huge Navigator HIST1H1A [HugePedia]
snp3D : Map Gene to Disease3024
BioCentury BCIQHIST1H1A
ClinGenHIST1H1A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3024
Chemical/Pharm GKB GenePA29093
Clinical trialHIST1H1A
Miscellaneous
canSAR (ICR)HIST1H1A (select the gene name)
Probes
Litterature
PubMed138 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIST1H1A
EVEXHIST1H1A
GoPubMedHIST1H1A
iHOPHIST1H1A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 22 16:29:00 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.