Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

HIST1H1B (histone cluster 1 H1 family member b)

Identity

Alias_namesH1F5
H1 histone family, member 5
histone 1, H1b
histone cluster 1, H1b
Alias_symbol (synonym)H1.5
H1b
H1s-3
Other aliasH1
H1B
HGNC (Hugo) HIST1H1B
LocusID (NCBI) 3009
Atlas_Id 53525
Location 6p22.1  [Link to chromosome band 6p22]
Location_base_pair Starts at 27866792 and ends at 27867581 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;7)(p22;p14) MPLKIP/HIST1H1B


External links

Nomenclature
HGNC (Hugo)HIST1H1B   4719
Cards
Entrez_Gene (NCBI)HIST1H1B  3009  histone cluster 1 H1 family member b
AliasesH1; H1.5; H1B; H1F5; 
H1s-3
GeneCards (Weizmann)HIST1H1B
Ensembl hg19 (Hinxton)ENSG00000184357 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184357 [Gene_View]  ENSG00000184357 [Sequence]  chr6:27866792-27867581 [Contig_View]  HIST1H1B [Vega]
ICGC DataPortalENSG00000184357
TCGA cBioPortalHIST1H1B
AceView (NCBI)HIST1H1B
Genatlas (Paris)HIST1H1B
WikiGenes3009
SOURCE (Princeton)HIST1H1B
Genetics Home Reference (NIH)HIST1H1B
Genomic and cartography
GoldenPath hg38 (UCSC)HIST1H1B  -     chr6:27866792-27867581 -  6p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HIST1H1B  -     6p22.1   [Description]    (hg19-Feb_2009)
EnsemblHIST1H1B - 6p22.1 [CytoView hg19]  HIST1H1B - 6p22.1 [CytoView hg38]
Mapping of homologs : NCBIHIST1H1B [Mapview hg19]  HIST1H1B [Mapview hg38]
OMIM142711   
Gene and transcription
Genbank (Entrez)BC069101 BC101581 BC101583
RefSeq transcript (Entrez)NM_005322
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HIST1H1B
Cluster EST : UnigeneHs.131956 [ NCBI ]
CGAP (NCI)Hs.131956
Alternative Splicing GalleryENSG00000184357
Gene ExpressionHIST1H1B [ NCBI-GEO ]   HIST1H1B [ EBI - ARRAY_EXPRESS ]   HIST1H1B [ SEEK ]   HIST1H1B [ MEM ]
Gene Expression Viewer (FireBrowse)HIST1H1B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3009
GTEX Portal (Tissue expression)HIST1H1B
Human Protein AtlasENSG00000184357-HIST1H1B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP16401   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP16401  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP16401
Splice isoforms : SwissVarP16401
PhosPhoSitePlusP16401
Domaine pattern : Prosite (Expaxy)H15 (PS51504)   
Domains : Interpro (EBI)Histone_H1/H5_H15    Histone_H5    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)Linker_histone (PF00538)   
Domain families : Pfam (NCBI)pfam00538   
Domain families : Smart (EMBL)H15 (SM00526)  
Conserved Domain (NCBI)HIST1H1B
DMDM Disease mutations3009
Blocks (Seattle)HIST1H1B
PDB (SRS)2FE2    2RHI   
PDB (PDBSum)2FE2    2RHI   
PDB (IMB)2FE2    2RHI   
PDB (RSDB)2FE2    2RHI   
Structural Biology KnowledgeBase2FE2    2RHI   
SCOP (Structural Classification of Proteins)2FE2    2RHI   
CATH (Classification of proteins structures)2FE2    2RHI   
SuperfamilyP16401
Human Protein Atlas [tissue]ENSG00000184357-HIST1H1B [tissue]
Peptide AtlasP16401
HPRD00821
IPIIPI00217468   IPI00815867   
Protein Interaction databases
DIP (DOE-UCLA)P16401
IntAct (EBI)P16401
FunCoupENSG00000184357
BioGRIDHIST1H1B
STRING (EMBL)HIST1H1B
ZODIACHIST1H1B
Ontologies - Pathways
QuickGOP16401
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  nucleosome  nuclear chromatin  RNA binding  nucleus  nuclear heterochromatin  chromatin organization  nucleosome assembly  positive regulation of cell growth  chromatin DNA binding  histone deacetylase binding  protein stabilization  positive regulation of histone H3-K9 methylation  extracellular exosome  establishment of protein localization to chromatin  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  nucleosome  nuclear chromatin  RNA binding  nucleus  nuclear heterochromatin  chromatin organization  nucleosome assembly  positive regulation of cell growth  chromatin DNA binding  histone deacetylase binding  protein stabilization  positive regulation of histone H3-K9 methylation  extracellular exosome  establishment of protein localization to chromatin  
NDEx NetworkHIST1H1B
Atlas of Cancer Signalling NetworkHIST1H1B
Wikipedia pathwaysHIST1H1B
Orthology - Evolution
OrthoDB3009
GeneTree (enSembl)ENSG00000184357
Phylogenetic Trees/Animal Genes : TreeFamHIST1H1B
HOVERGENP16401
HOGENOMP16401
Homologs : HomoloGeneHIST1H1B
Homology/Alignments : Family Browser (UCSC)HIST1H1B
Gene fusions - Rearrangements
Fusion : QuiverHIST1H1B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIST1H1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIST1H1B
dbVarHIST1H1B
ClinVarHIST1H1B
1000_GenomesHIST1H1B 
Exome Variant ServerHIST1H1B
ExAC (Exome Aggregation Consortium)ENSG00000184357
GNOMAD BrowserENSG00000184357
Genetic variants : HAPMAP3009
Genomic Variants (DGV)HIST1H1B [DGVbeta]
DECIPHERHIST1H1B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHIST1H1B 
Mutations
ICGC Data PortalHIST1H1B 
TCGA Data PortalHIST1H1B 
Broad Tumor PortalHIST1H1B
OASIS PortalHIST1H1B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHIST1H1B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHIST1H1B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIST1H1B
DgiDB (Drug Gene Interaction Database)HIST1H1B
DoCM (Curated mutations)HIST1H1B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIST1H1B (select a term)
intoGenHIST1H1B
Cancer3DHIST1H1B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM142711   
Orphanet
DisGeNETHIST1H1B
MedgenHIST1H1B
Genetic Testing Registry HIST1H1B
NextProtP16401 [Medical]
TSGene3009
GENETestsHIST1H1B
Target ValidationHIST1H1B
Huge Navigator HIST1H1B [HugePedia]
snp3D : Map Gene to Disease3009
BioCentury BCIQHIST1H1B
ClinGenHIST1H1B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3009
Chemical/Pharm GKB GenePA29097
Clinical trialHIST1H1B
Miscellaneous
canSAR (ICR)HIST1H1B (select the gene name)
Probes
Litterature
PubMed97 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIST1H1B
EVEXHIST1H1B
GoPubMedHIST1H1B
iHOPHIST1H1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 22 16:29:00 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.