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HIST1H1E (histone cluster 1 H1 family member e)

Identity

Alias_namesH1F4
H1 histone family, member 4
histone 1, H1e
histone cluster 1, H1e
Alias_symbol (synonym)H1.4
H1e
H1s-4
Other aliasH1E
RMNS
dJ221C16.5
HGNC (Hugo) HIST1H1E
LocusID (NCBI) 3008
Atlas_Id 53757
Location 6p22.2  [Link to chromosome band 6p22]
Location_base_pair Starts at 26156331 and ends at 26157115 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HIST1H1E (6p22.2) / EEF1A1 (6q13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HIST1H1E   4718
Cards
Entrez_Gene (NCBI)HIST1H1E  3008  histone cluster 1 H1 family member e
AliasesH1.4; H1E; H1F4; H1s-4; 
RMNS; dJ221C16.5
GeneCards (Weizmann)HIST1H1E
Ensembl hg19 (Hinxton)ENSG00000168298 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168298 [Gene_View]  ENSG00000168298 [Sequence]  chr6:26156331-26157115 [Contig_View]  HIST1H1E [Vega]
ICGC DataPortalENSG00000168298
TCGA cBioPortalHIST1H1E
AceView (NCBI)HIST1H1E
Genatlas (Paris)HIST1H1E
WikiGenes3008
SOURCE (Princeton)HIST1H1E
Genetics Home Reference (NIH)HIST1H1E
Genomic and cartography
GoldenPath hg38 (UCSC)HIST1H1E  -     chr6:26156331-26157115 +  6p22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HIST1H1E  -     6p22.2   [Description]    (hg19-Feb_2009)
EnsemblHIST1H1E - 6p22.2 [CytoView hg19]  HIST1H1E - 6p22.2 [CytoView hg38]
Mapping of homologs : NCBIHIST1H1E [Mapview hg19]  HIST1H1E [Mapview hg38]
OMIM142220   617537   
Gene and transcription
Genbank (Entrez)AK313681 BC055095 BC096168 BC096169 BC096170
RefSeq transcript (Entrez)NM_005321
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HIST1H1E
Cluster EST : UnigeneHs.248133 [ NCBI ]
CGAP (NCI)Hs.248133
Alternative Splicing GalleryENSG00000168298
Gene ExpressionHIST1H1E [ NCBI-GEO ]   HIST1H1E [ EBI - ARRAY_EXPRESS ]   HIST1H1E [ SEEK ]   HIST1H1E [ MEM ]
Gene Expression Viewer (FireBrowse)HIST1H1E [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3008
GTEX Portal (Tissue expression)HIST1H1E
Human Protein AtlasENSG00000168298-HIST1H1E [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP10412   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP10412  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP10412
Splice isoforms : SwissVarP10412
PhosPhoSitePlusP10412
Domaine pattern : Prosite (Expaxy)H15 (PS51504)   
Domains : Interpro (EBI)Histone_H1/H5_H15    Histone_H5    WH-like_DNA-bd_sf    WH_DNA-bd_sf   
Domain families : Pfam (Sanger)Linker_histone (PF00538)   
Domain families : Pfam (NCBI)pfam00538   
Domain families : Smart (EMBL)H15 (SM00526)  
Conserved Domain (NCBI)HIST1H1E
DMDM Disease mutations3008
Blocks (Seattle)HIST1H1E
PDB (SRS)3TZD    5JJZ   
PDB (PDBSum)3TZD    5JJZ   
PDB (IMB)3TZD    5JJZ   
PDB (RSDB)3TZD    5JJZ   
Structural Biology KnowledgeBase3TZD    5JJZ   
SCOP (Structural Classification of Proteins)3TZD    5JJZ   
CATH (Classification of proteins structures)3TZD    5JJZ   
SuperfamilyP10412
Human Protein Atlas [tissue]ENSG00000168298-HIST1H1E [tissue]
Peptide AtlasP10412
HPRD07513
IPIIPI00217467   
Protein Interaction databases
DIP (DOE-UCLA)P10412
IntAct (EBI)P10412
FunCoupENSG00000168298
BioGRIDHIST1H1E
STRING (EMBL)HIST1H1E
ZODIACHIST1H1E
Ontologies - Pathways
QuickGOP10412
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  nuclear nucleosome  double-stranded DNA binding  RNA binding  calcium ion binding  protein binding  ATP binding  GTP binding  nucleus  nuclear heterochromatin  nucleosome assembly  AMP binding  nucleosome positioning  chromatin DNA binding  dATP binding  ADP binding  histone H3-K4 trimethylation  histone H3-K27 trimethylation  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  nuclear nucleosome  double-stranded DNA binding  RNA binding  calcium ion binding  protein binding  ATP binding  GTP binding  nucleus  nuclear heterochromatin  nucleosome assembly  AMP binding  nucleosome positioning  chromatin DNA binding  dATP binding  ADP binding  histone H3-K4 trimethylation  histone H3-K27 trimethylation  
NDEx NetworkHIST1H1E
Atlas of Cancer Signalling NetworkHIST1H1E
Wikipedia pathwaysHIST1H1E
Orthology - Evolution
OrthoDB3008
GeneTree (enSembl)ENSG00000168298
Phylogenetic Trees/Animal Genes : TreeFamHIST1H1E
HOVERGENP10412
HOGENOMP10412
Homologs : HomoloGeneHIST1H1E
Homology/Alignments : Family Browser (UCSC)HIST1H1E
Gene fusions - Rearrangements
Fusion : QuiverHIST1H1E
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIST1H1E [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIST1H1E
dbVarHIST1H1E
ClinVarHIST1H1E
1000_GenomesHIST1H1E 
Exome Variant ServerHIST1H1E
ExAC (Exome Aggregation Consortium)ENSG00000168298
GNOMAD BrowserENSG00000168298
Varsome BrowserHIST1H1E
Genetic variants : HAPMAP3008
Genomic Variants (DGV)HIST1H1E [DGVbeta]
DECIPHERHIST1H1E [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHIST1H1E 
Mutations
ICGC Data PortalHIST1H1E 
TCGA Data PortalHIST1H1E 
Broad Tumor PortalHIST1H1E
OASIS PortalHIST1H1E [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHIST1H1E  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHIST1H1E
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIST1H1E
DgiDB (Drug Gene Interaction Database)HIST1H1E
DoCM (Curated mutations)HIST1H1E (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIST1H1E (select a term)
intoGenHIST1H1E
Cancer3DHIST1H1E(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM142220    617537   
Orphanet
DisGeNETHIST1H1E
MedgenHIST1H1E
Genetic Testing Registry HIST1H1E
NextProtP10412 [Medical]
TSGene3008
GENETestsHIST1H1E
Target ValidationHIST1H1E
Huge Navigator HIST1H1E [HugePedia]
snp3D : Map Gene to Disease3008
BioCentury BCIQHIST1H1E
ClinGenHIST1H1E
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3008
Chemical/Pharm GKB GenePA29096
Clinical trialHIST1H1E
Miscellaneous
canSAR (ICR)HIST1H1E (select the gene name)
Probes
Litterature
PubMed64 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIST1H1E
EVEXHIST1H1E
GoPubMedHIST1H1E
iHOPHIST1H1E
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 27 11:26:56 CEST 2018

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