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HIST1H2AE (histone cluster 1 H2A family member e)

Identity

Alias_namesH2AFA
H2A histone family, member A
histone 1, H2ae
histone cluster 1, H2ae
Alias_symbol (synonym)H2A/a
H2A.1
Other aliasH2A.2
HGNC (Hugo) HIST1H2AE
LocusID (NCBI) 3012
Atlas_Id 56527
Location 6p22.2  [Link to chromosome band 6p22]
Location_base_pair Starts at 26216920 and ends at 26217483 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HIST1H2AE   4724
Cards
Entrez_Gene (NCBI)HIST1H2AE  3012  histone cluster 1 H2A family member e
AliasesH2A.1; H2A.2; H2A/a; H2AFA
GeneCards (Weizmann)HIST1H2AE
Ensembl hg19 (Hinxton)ENSG00000277075 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000277075 [Gene_View]  ENSG00000277075 [Sequence]  chr6:26216920-26217483 [Contig_View]  HIST1H2AE [Vega]
ICGC DataPortalENSG00000277075
TCGA cBioPortalHIST1H2AE
AceView (NCBI)HIST1H2AE
Genatlas (Paris)HIST1H2AE
WikiGenes3012
SOURCE (Princeton)HIST1H2AE
Genetics Home Reference (NIH)HIST1H2AE
Genomic and cartography
GoldenPath hg38 (UCSC)HIST1H2AE  -     chr6:26216920-26217483 +  6p22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HIST1H2AE  -     6p22.2   [Description]    (hg19-Feb_2009)
EnsemblHIST1H2AE - 6p22.2 [CytoView hg19]  HIST1H2AE - 6p22.2 [CytoView hg38]
Mapping of homologs : NCBIHIST1H2AE [Mapview hg19]  HIST1H2AE [Mapview hg38]
OMIM602786   
Gene and transcription
Genbank (Entrez)AK311824 BC093836 BC093862
RefSeq transcript (Entrez)NM_021052
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HIST1H2AE
Cluster EST : UnigeneHs.709162 [ NCBI ]
CGAP (NCI)Hs.709162
Alternative Splicing GalleryENSG00000277075
Gene ExpressionHIST1H2AE [ NCBI-GEO ]   HIST1H2AE [ EBI - ARRAY_EXPRESS ]   HIST1H2AE [ SEEK ]   HIST1H2AE [ MEM ]
Gene Expression Viewer (FireBrowse)HIST1H2AE [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3012
GTEX Portal (Tissue expression)HIST1H2AE
Human Protein AtlasENSG00000277075-HIST1H2AE [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP04908   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP04908  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP04908
Splice isoforms : SwissVarP04908
PhosPhoSitePlusP04908
Domaine pattern : Prosite (Expaxy)HISTONE_H2A (PS00046)   
Domains : Interpro (EBI)Histone-fold    Histone_H2A    Histone_H2A/H2B/H3    Histone_H2A_C    Histone_H2A_CS   
Domain families : Pfam (Sanger)Histone (PF00125)    Histone_H2A_C (PF16211)   
Domain families : Pfam (NCBI)pfam00125    pfam16211   
Domain families : Smart (EMBL)H2A (SM00414)  
Conserved Domain (NCBI)HIST1H2AE
DMDM Disease mutations3012
Blocks (Seattle)HIST1H2AE
PDB (SRS)2CV5    2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WKJ    3WTP    3X1S    3X1V    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B40    5CPI    5CPJ    5CPK    5GSE    5GTC    5GXQ    5JRG    5X7X    5XF3    5XF4    5XF5    6BUZ   
PDB (PDBSum)2CV5    2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WKJ    3WTP    3X1S    3X1V    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B40    5CPI    5CPJ    5CPK    5GSE    5GTC    5GXQ    5JRG    5X7X    5XF3    5XF4    5XF5    6BUZ   
PDB (IMB)2CV5    2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WKJ    3WTP    3X1S    3X1V    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B40    5CPI    5CPJ    5CPK    5GSE    5GTC    5GXQ    5JRG    5X7X    5XF3    5XF4    5XF5    6BUZ   
PDB (RSDB)2CV5    2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WKJ    3WTP    3X1S    3X1V    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B40    5CPI    5CPJ    5CPK    5GSE    5GTC    5GXQ    5JRG    5X7X    5XF3    5XF4    5XF5    6BUZ   
Structural Biology KnowledgeBase2CV5    2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WKJ    3WTP    3X1S    3X1V    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B40    5CPI    5CPJ    5CPK    5GSE    5GTC    5GXQ    5JRG    5X7X    5XF3    5XF4    5XF5    6BUZ   
SCOP (Structural Classification of Proteins)2CV5    2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WKJ    3WTP    3X1S    3X1V    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B40    5CPI    5CPJ    5CPK    5GSE    5GTC    5GXQ    5JRG    5X7X    5XF3    5XF4    5XF5    6BUZ   
CATH (Classification of proteins structures)2CV5    2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WKJ    3WTP    3X1S    3X1V    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B40    5CPI    5CPJ    5CPK    5GSE    5GTC    5GXQ    5JRG    5X7X    5XF3    5XF4    5XF5    6BUZ   
SuperfamilyP04908
Human Protein Atlas [tissue]ENSG00000277075-HIST1H2AE [tissue]
Peptide AtlasP04908
HPRD04152
Protein Interaction databases
DIP (DOE-UCLA)P04908
IntAct (EBI)P04908
FunCoupENSG00000277075
BioGRIDHIST1H2AE
STRING (EMBL)HIST1H2AE
ZODIACHIST1H2AE
Ontologies - Pathways
QuickGOP04908
Ontology : AmiGOnucleosome  nuclear chromatin  DNA binding  DNA binding  protein binding  nucleus  nucleus  chromatin organization  chromatin silencing  negative regulation of cell proliferation  protein heterodimerization activity  extracellular exosome  
Ontology : EGO-EBInucleosome  nuclear chromatin  DNA binding  DNA binding  protein binding  nucleus  nucleus  chromatin organization  chromatin silencing  negative regulation of cell proliferation  protein heterodimerization activity  extracellular exosome  
Pathways : KEGGAlcoholism    Systemic lupus erythematosus   
NDEx NetworkHIST1H2AE
Atlas of Cancer Signalling NetworkHIST1H2AE
Wikipedia pathwaysHIST1H2AE
Orthology - Evolution
OrthoDB3012
GeneTree (enSembl)ENSG00000277075
Phylogenetic Trees/Animal Genes : TreeFamHIST1H2AE
HOVERGENP04908
HOGENOMP04908
Homologs : HomoloGeneHIST1H2AE
Homology/Alignments : Family Browser (UCSC)HIST1H2AE
Gene fusions - Rearrangements
Fusion : QuiverHIST1H2AE
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIST1H2AE [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIST1H2AE
dbVarHIST1H2AE
ClinVarHIST1H2AE
1000_GenomesHIST1H2AE 
Exome Variant ServerHIST1H2AE
ExAC (Exome Aggregation Consortium)ENSG00000277075
GNOMAD BrowserENSG00000277075
Varsome BrowserHIST1H2AE
Genetic variants : HAPMAP3012
Genomic Variants (DGV)HIST1H2AE [DGVbeta]
DECIPHERHIST1H2AE [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHIST1H2AE 
Mutations
ICGC Data PortalHIST1H2AE 
TCGA Data PortalHIST1H2AE 
Broad Tumor PortalHIST1H2AE
OASIS PortalHIST1H2AE [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHIST1H2AE  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHIST1H2AE
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIST1H2AE
DgiDB (Drug Gene Interaction Database)HIST1H2AE
DoCM (Curated mutations)HIST1H2AE (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIST1H2AE (select a term)
intoGenHIST1H2AE
Cancer3DHIST1H2AE(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602786   
Orphanet
DisGeNETHIST1H2AE
MedgenHIST1H2AE
Genetic Testing Registry HIST1H2AE
NextProtP04908 [Medical]
TSGene3012
GENETestsHIST1H2AE
Target ValidationHIST1H2AE
Huge Navigator HIST1H2AE [HugePedia]
snp3D : Map Gene to Disease3012
BioCentury BCIQHIST1H2AE
ClinGenHIST1H2AE
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3012
Chemical/Pharm GKB GenePA29100
Clinical trialHIST1H2AE
Miscellaneous
canSAR (ICR)HIST1H2AE (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIST1H2AE
EVEXHIST1H2AE
GoPubMedHIST1H2AE
iHOPHIST1H2AE
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 27 11:26:57 CEST 2018

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