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HIST1H2AK (histone cluster 1 H2A family member k)

Identity

Alias_namesH2AFD
H2A histone family, member D
histone 1, H2ak
histone cluster 1, H2ak
Alias_symbol (synonym)H2A/d
Other alias
HGNC (Hugo) HIST1H2AK
LocusID (NCBI) 8330
Atlas_Id 64284
Location 6p22.1  [Link to chromosome band 6p22]
Location_base_pair Starts at 27837880 and ends at 27838339 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HIST1H2AK   4726
Cards
Entrez_Gene (NCBI)HIST1H2AK  8330  histone cluster 1 H2A family member k
AliasesH2A/d; H2AFD
GeneCards (Weizmann)HIST1H2AK
Ensembl hg19 (Hinxton)ENSG00000275221 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000275221 [Gene_View]  ENSG00000275221 [Sequence]  chr6:27837880-27838339 [Contig_View]  HIST1H2AK [Vega]
ICGC DataPortalENSG00000275221
TCGA cBioPortalHIST1H2AK
AceView (NCBI)HIST1H2AK
Genatlas (Paris)HIST1H2AK
WikiGenes8330
SOURCE (Princeton)HIST1H2AK
Genetics Home Reference (NIH)HIST1H2AK
Genomic and cartography
GoldenPath hg38 (UCSC)HIST1H2AK  -     chr6:27837880-27838339 -  6p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HIST1H2AK  -     6p22.1   [Description]    (hg19-Feb_2009)
EnsemblHIST1H2AK - 6p22.1 [CytoView hg19]  HIST1H2AK - 6p22.1 [CytoView hg38]
Mapping of homologs : NCBIHIST1H2AK [Mapview hg19]  HIST1H2AK [Mapview hg38]
OMIM602788   
Gene and transcription
Genbank (Entrez)AK311941 BC034487 BC104198 BC104199
RefSeq transcript (Entrez)NM_003510
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HIST1H2AK
Cluster EST : UnigeneHs.734717 [ NCBI ]
CGAP (NCI)Hs.734717
Alternative Splicing GalleryENSG00000275221
Gene ExpressionHIST1H2AK [ NCBI-GEO ]   HIST1H2AK [ EBI - ARRAY_EXPRESS ]   HIST1H2AK [ SEEK ]   HIST1H2AK [ MEM ]
Gene Expression Viewer (FireBrowse)HIST1H2AK [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8330
GTEX Portal (Tissue expression)HIST1H2AK
Human Protein AtlasENSG00000275221-HIST1H2AK [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP0C0S8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP0C0S8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP0C0S8
Splice isoforms : SwissVarP0C0S8
PhosPhoSitePlusP0C0S8
Domaine pattern : Prosite (Expaxy)HISTONE_H2A (PS00046)   
Domains : Interpro (EBI)Histone-fold    Histone_H2A    Histone_H2A/H2B/H3    Histone_H2A_C    Histone_H2A_CS   
Domain families : Pfam (Sanger)Histone (PF00125)    Histone_H2A_C (PF16211)   
Domain families : Pfam (NCBI)pfam00125    pfam16211   
Domain families : Smart (EMBL)H2A (SM00414)  
Conserved Domain (NCBI)HIST1H2AK
DMDM Disease mutations8330
Blocks (Seattle)HIST1H2AK
PDB (SRS)4QYL    5KGF   
PDB (PDBSum)4QYL    5KGF   
PDB (IMB)4QYL    5KGF   
PDB (RSDB)4QYL    5KGF   
Structural Biology KnowledgeBase4QYL    5KGF   
SCOP (Structural Classification of Proteins)4QYL    5KGF   
CATH (Classification of proteins structures)4QYL    5KGF   
SuperfamilyP0C0S8
Human Protein Atlas [tissue]ENSG00000275221-HIST1H2AK [tissue]
Peptide AtlasP0C0S8
HPRD09100
Protein Interaction databases
DIP (DOE-UCLA)P0C0S8
IntAct (EBI)P0C0S8
FunCoupENSG00000275221
BioGRIDHIST1H2AK
STRING (EMBL)HIST1H2AK
ZODIACHIST1H2AK
Ontologies - Pathways
QuickGOP0C0S8
Ontology : AmiGOnucleosome  nuclear chromatin  molecular_function  DNA binding  protein binding  nucleus  chromatin silencing  biological_process  enzyme binding  protein heterodimerization activity  extracellular exosome  
Ontology : EGO-EBInucleosome  nuclear chromatin  molecular_function  DNA binding  protein binding  nucleus  chromatin silencing  biological_process  enzyme binding  protein heterodimerization activity  extracellular exosome  
NDEx NetworkHIST1H2AK
Atlas of Cancer Signalling NetworkHIST1H2AK
Wikipedia pathwaysHIST1H2AK
Orthology - Evolution
OrthoDB8330
GeneTree (enSembl)ENSG00000275221
Phylogenetic Trees/Animal Genes : TreeFamHIST1H2AK
HOVERGENP0C0S8
HOGENOMP0C0S8
Homologs : HomoloGeneHIST1H2AK
Homology/Alignments : Family Browser (UCSC)HIST1H2AK
Gene fusions - Rearrangements
Fusion : QuiverHIST1H2AK
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIST1H2AK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIST1H2AK
dbVarHIST1H2AK
ClinVarHIST1H2AK
1000_GenomesHIST1H2AK 
Exome Variant ServerHIST1H2AK
ExAC (Exome Aggregation Consortium)ENSG00000275221
GNOMAD BrowserENSG00000275221
Varsome BrowserHIST1H2AK
Genetic variants : HAPMAP8330
Genomic Variants (DGV)HIST1H2AK [DGVbeta]
DECIPHERHIST1H2AK [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHIST1H2AK 
Mutations
ICGC Data PortalHIST1H2AK 
TCGA Data PortalHIST1H2AK 
Broad Tumor PortalHIST1H2AK
OASIS PortalHIST1H2AK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHIST1H2AK  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHIST1H2AK
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIST1H2AK
DgiDB (Drug Gene Interaction Database)HIST1H2AK
DoCM (Curated mutations)HIST1H2AK (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIST1H2AK (select a term)
intoGenHIST1H2AK
Cancer3DHIST1H2AK(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602788   
Orphanet
DisGeNETHIST1H2AK
MedgenHIST1H2AK
Genetic Testing Registry HIST1H2AK
NextProtP0C0S8 [Medical]
TSGene8330
GENETestsHIST1H2AK
Target ValidationHIST1H2AK
Huge Navigator HIST1H2AK [HugePedia]
snp3D : Map Gene to Disease8330
BioCentury BCIQHIST1H2AK
ClinGenHIST1H2AK
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8330
Chemical/Pharm GKB GenePA29103
Clinical trialHIST1H2AK
Miscellaneous
canSAR (ICR)HIST1H2AK (select the gene name)
Probes
Litterature
PubMed1 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIST1H2AK
EVEXHIST1H2AK
GoPubMedHIST1H2AK
iHOPHIST1H2AK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 13:48:55 CEST 2018

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