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HIST1H2AL (histone cluster 1 H2A family member l)

Identity

Alias_namesH2AFI
H2A histone family, member I
histone 1, H2al
histone cluster 1, H2al
Alias_symbol (synonym)H2A/i
dJ193B12.9
Other aliasH2A.i
HGNC (Hugo) HIST1H2AL
LocusID (NCBI) 8332
Atlas_Id 64285
Location 6p22.1  [Link to chromosome band 6p22]
Location_base_pair Starts at 27865329 and ends at 27865798 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HIST1H2AL   4730
Cards
Entrez_Gene (NCBI)HIST1H2AL  8332  histone cluster 1 H2A family member l
AliasesH2A.i; H2A/i; H2AFI; dJ193B12.9
GeneCards (Weizmann)HIST1H2AL
Ensembl hg19 (Hinxton)ENSG00000276903 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000276903 [Gene_View]  chr6:27865329-27865798 [Contig_View]  HIST1H2AL [Vega]
ICGC DataPortalENSG00000276903
TCGA cBioPortalHIST1H2AL
AceView (NCBI)HIST1H2AL
Genatlas (Paris)HIST1H2AL
WikiGenes8332
SOURCE (Princeton)HIST1H2AL
Genetics Home Reference (NIH)HIST1H2AL
Genomic and cartography
GoldenPath hg38 (UCSC)HIST1H2AL  -     chr6:27865329-27865798 +  6p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HIST1H2AL  -     6p22.1   [Description]    (hg19-Feb_2009)
EnsemblHIST1H2AL - 6p22.1 [CytoView hg19]  HIST1H2AL - 6p22.1 [CytoView hg38]
Mapping of homologs : NCBIHIST1H2AL [Mapview hg19]  HIST1H2AL [Mapview hg38]
OMIM602793   
Gene and transcription
Genbank (Entrez)BC069306 BC112072 HQ448466
RefSeq transcript (Entrez)NM_003511
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HIST1H2AL
Cluster EST : UnigeneHs.233568 [ NCBI ]
CGAP (NCI)Hs.233568
Alternative Splicing GalleryENSG00000276903
Gene ExpressionHIST1H2AL [ NCBI-GEO ]   HIST1H2AL [ EBI - ARRAY_EXPRESS ]   HIST1H2AL [ SEEK ]   HIST1H2AL [ MEM ]
Gene Expression Viewer (FireBrowse)HIST1H2AL [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8332
GTEX Portal (Tissue expression)HIST1H2AL
Human Protein AtlasENSG00000276903-HIST1H2AL [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP0C0S8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP0C0S8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP0C0S8
Splice isoforms : SwissVarP0C0S8
PhosPhoSitePlusP0C0S8
Domaine pattern : Prosite (Expaxy)HISTONE_H2A (PS00046)   
Domains : Interpro (EBI)Histone-fold    Histone_H2A    Histone_H2A/H2B/H3    Histone_H2A_C    Histone_H2A_CS   
Domain families : Pfam (Sanger)Histone (PF00125)    Histone_H2A_C (PF16211)   
Domain families : Pfam (NCBI)pfam00125    pfam16211   
Domain families : Smart (EMBL)H2A (SM00414)  
Conserved Domain (NCBI)HIST1H2AL
DMDM Disease mutations8332
Blocks (Seattle)HIST1H2AL
PDB (SRS)4QYL    5KGF   
PDB (PDBSum)4QYL    5KGF   
PDB (IMB)4QYL    5KGF   
PDB (RSDB)4QYL    5KGF   
Structural Biology KnowledgeBase4QYL    5KGF   
SCOP (Structural Classification of Proteins)4QYL    5KGF   
CATH (Classification of proteins structures)4QYL    5KGF   
SuperfamilyP0C0S8
Human Protein Atlas [tissue]ENSG00000276903-HIST1H2AL [tissue]
Peptide AtlasP0C0S8
HPRD09103
Protein Interaction databases
DIP (DOE-UCLA)P0C0S8
IntAct (EBI)P0C0S8
FunCoupENSG00000276903
BioGRIDHIST1H2AL
STRING (EMBL)HIST1H2AL
ZODIACHIST1H2AL
Ontologies - Pathways
QuickGOP0C0S8
Ontology : AmiGOnucleosome  nuclear chromatin  DNA binding  protein binding  nucleus  chromatin silencing  biological_process  enzyme binding  protein heterodimerization activity  extracellular exosome  
Ontology : EGO-EBInucleosome  nuclear chromatin  DNA binding  protein binding  nucleus  chromatin silencing  biological_process  enzyme binding  protein heterodimerization activity  extracellular exosome  
NDEx NetworkHIST1H2AL
Atlas of Cancer Signalling NetworkHIST1H2AL
Wikipedia pathwaysHIST1H2AL
Orthology - Evolution
OrthoDB8332
GeneTree (enSembl)ENSG00000276903
Phylogenetic Trees/Animal Genes : TreeFamHIST1H2AL
HOVERGENP0C0S8
HOGENOMP0C0S8
Homologs : HomoloGeneHIST1H2AL
Homology/Alignments : Family Browser (UCSC)HIST1H2AL
Gene fusions - Rearrangements
Fusion : QuiverHIST1H2AL
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIST1H2AL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIST1H2AL
dbVarHIST1H2AL
ClinVarHIST1H2AL
1000_GenomesHIST1H2AL 
Exome Variant ServerHIST1H2AL
ExAC (Exome Aggregation Consortium)ENSG00000276903
GNOMAD BrowserENSG00000276903
Genetic variants : HAPMAP8332
Genomic Variants (DGV)HIST1H2AL [DGVbeta]
DECIPHERHIST1H2AL [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHIST1H2AL 
Mutations
ICGC Data PortalHIST1H2AL 
TCGA Data PortalHIST1H2AL 
Broad Tumor PortalHIST1H2AL
OASIS PortalHIST1H2AL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHIST1H2AL  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHIST1H2AL
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIST1H2AL
DgiDB (Drug Gene Interaction Database)HIST1H2AL
DoCM (Curated mutations)HIST1H2AL (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIST1H2AL (select a term)
intoGenHIST1H2AL
Cancer3DHIST1H2AL(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602793   
Orphanet
DisGeNETHIST1H2AL
MedgenHIST1H2AL
Genetic Testing Registry HIST1H2AL
NextProtP0C0S8 [Medical]
TSGene8332
GENETestsHIST1H2AL
Target ValidationHIST1H2AL
Huge Navigator HIST1H2AL [HugePedia]
snp3D : Map Gene to Disease8332
BioCentury BCIQHIST1H2AL
ClinGenHIST1H2AL
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8332
Chemical/Pharm GKB GenePA29107
Clinical trialHIST1H2AL
Miscellaneous
canSAR (ICR)HIST1H2AL (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIST1H2AL
EVEXHIST1H2AL
GoPubMedHIST1H2AL
iHOPHIST1H2AL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Feb 23 18:21:17 CET 2018

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