Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HIST1H2AM (histone cluster 1 H2A family member m)

Identity

Alias_namesH2AFN
H2A histone family, member N
histone 1, H2am
histone cluster 1, H2am
Alias_symbol (synonym)H2A/n
H2A.1
Other aliasdJ193B12.1
HGNC (Hugo) HIST1H2AM
LocusID (NCBI) 8336
Atlas_Id 64286
Location 6p22.1  [Link to chromosome band 6p22]
Location_base_pair Starts at 27892699 and ends at 27893185 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HIST1H2AM (6p22.1) / EEF1A1 (6q13)HIST1H2AM (6p22.1) / GPM6B (Xp22.2)HIST1H2AM (6p22.1) / HRH1 (3p25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HIST1H2AM   4735
Cards
Entrez_Gene (NCBI)HIST1H2AM  8336  histone cluster 1 H2A family member m
AliasesH2A.1; H2A/n; H2AFN; dJ193B12.1
GeneCards (Weizmann)HIST1H2AM
Ensembl hg19 (Hinxton)ENSG00000278677 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000278677 [Gene_View]  ENSG00000278677 [Sequence]  chr6:27892699-27893185 [Contig_View]  HIST1H2AM [Vega]
ICGC DataPortalENSG00000278677
TCGA cBioPortalHIST1H2AM
AceView (NCBI)HIST1H2AM
Genatlas (Paris)HIST1H2AM
WikiGenes8336
SOURCE (Princeton)HIST1H2AM
Genetics Home Reference (NIH)HIST1H2AM
Genomic and cartography
GoldenPath hg38 (UCSC)HIST1H2AM  -     chr6:27892699-27893185 -  6p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HIST1H2AM  -     6p22.1   [Description]    (hg19-Feb_2009)
EnsemblHIST1H2AM - 6p22.1 [CytoView hg19]  HIST1H2AM - 6p22.1 [CytoView hg38]
Mapping of homologs : NCBIHIST1H2AM [Mapview hg19]  HIST1H2AM [Mapview hg38]
OMIM602796   
Gene and transcription
Genbank (Entrez)AK312224 BC032686 BC032756 DQ891187 DQ894370
RefSeq transcript (Entrez)NM_003514
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HIST1H2AM
Cluster EST : UnigeneHs.134999 [ NCBI ]
CGAP (NCI)Hs.134999
Alternative Splicing GalleryENSG00000278677
Gene ExpressionHIST1H2AM [ NCBI-GEO ]   HIST1H2AM [ EBI - ARRAY_EXPRESS ]   HIST1H2AM [ SEEK ]   HIST1H2AM [ MEM ]
Gene Expression Viewer (FireBrowse)HIST1H2AM [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8336
GTEX Portal (Tissue expression)HIST1H2AM
Human Protein AtlasENSG00000278677-HIST1H2AM [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP0C0S8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP0C0S8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP0C0S8
Splice isoforms : SwissVarP0C0S8
PhosPhoSitePlusP0C0S8
Domaine pattern : Prosite (Expaxy)HISTONE_H2A (PS00046)   
Domains : Interpro (EBI)Histone-fold    Histone_H2A    Histone_H2A/H2B/H3    Histone_H2A_C    Histone_H2A_CS   
Domain families : Pfam (Sanger)Histone (PF00125)    Histone_H2A_C (PF16211)   
Domain families : Pfam (NCBI)pfam00125    pfam16211   
Domain families : Smart (EMBL)H2A (SM00414)  
Conserved Domain (NCBI)HIST1H2AM
DMDM Disease mutations8336
Blocks (Seattle)HIST1H2AM
PDB (SRS)4QYL    5KGF   
PDB (PDBSum)4QYL    5KGF   
PDB (IMB)4QYL    5KGF   
PDB (RSDB)4QYL    5KGF   
Structural Biology KnowledgeBase4QYL    5KGF   
SCOP (Structural Classification of Proteins)4QYL    5KGF   
CATH (Classification of proteins structures)4QYL    5KGF   
SuperfamilyP0C0S8
Human Protein Atlas [tissue]ENSG00000278677-HIST1H2AM [tissue]
Peptide AtlasP0C0S8
HPRD09106
Protein Interaction databases
DIP (DOE-UCLA)P0C0S8
IntAct (EBI)P0C0S8
FunCoupENSG00000278677
BioGRIDHIST1H2AM
STRING (EMBL)HIST1H2AM
ZODIACHIST1H2AM
Ontologies - Pathways
QuickGOP0C0S8
Ontology : AmiGOnucleosome  nuclear chromatin  DNA binding  protein binding  nucleus  chromatin silencing  biological_process  enzyme binding  protein heterodimerization activity  extracellular exosome  
Ontology : EGO-EBInucleosome  nuclear chromatin  DNA binding  protein binding  nucleus  chromatin silencing  biological_process  enzyme binding  protein heterodimerization activity  extracellular exosome  
NDEx NetworkHIST1H2AM
Atlas of Cancer Signalling NetworkHIST1H2AM
Wikipedia pathwaysHIST1H2AM
Orthology - Evolution
OrthoDB8336
GeneTree (enSembl)ENSG00000278677
Phylogenetic Trees/Animal Genes : TreeFamHIST1H2AM
HOVERGENP0C0S8
HOGENOMP0C0S8
Homologs : HomoloGeneHIST1H2AM
Homology/Alignments : Family Browser (UCSC)HIST1H2AM
Gene fusions - Rearrangements
Fusion : QuiverHIST1H2AM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIST1H2AM [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIST1H2AM
dbVarHIST1H2AM
ClinVarHIST1H2AM
1000_GenomesHIST1H2AM 
Exome Variant ServerHIST1H2AM
ExAC (Exome Aggregation Consortium)ENSG00000278677
GNOMAD BrowserENSG00000278677
Varsome BrowserHIST1H2AM
Genetic variants : HAPMAP8336
Genomic Variants (DGV)HIST1H2AM [DGVbeta]
DECIPHERHIST1H2AM [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHIST1H2AM 
Mutations
ICGC Data PortalHIST1H2AM 
TCGA Data PortalHIST1H2AM 
Broad Tumor PortalHIST1H2AM
OASIS PortalHIST1H2AM [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHIST1H2AM  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHIST1H2AM
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIST1H2AM
DgiDB (Drug Gene Interaction Database)HIST1H2AM
DoCM (Curated mutations)HIST1H2AM (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIST1H2AM (select a term)
intoGenHIST1H2AM
Cancer3DHIST1H2AM(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602796   
Orphanet
DisGeNETHIST1H2AM
MedgenHIST1H2AM
Genetic Testing Registry HIST1H2AM
NextProtP0C0S8 [Medical]
TSGene8336
GENETestsHIST1H2AM
Target ValidationHIST1H2AM
Huge Navigator HIST1H2AM [HugePedia]
snp3D : Map Gene to Disease8336
BioCentury BCIQHIST1H2AM
ClinGenHIST1H2AM
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8336
Chemical/Pharm GKB GenePA29112
Clinical trialHIST1H2AM
Miscellaneous
canSAR (ICR)HIST1H2AM (select the gene name)
Probes
Litterature
PubMed1 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIST1H2AM
EVEXHIST1H2AM
GoPubMedHIST1H2AM
iHOPHIST1H2AM
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 13:48:55 CEST 2018

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