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HIST1H2BD (histone cluster 1 H2B family member d)

Identity

Alias_namesH2BFB
H2B histone family, member B
histone 1, H2bd
histone cluster 1, H2bd
Alias_symbol (synonym)H2B/b
Other aliasH2B.1B
HIRIP2
dJ221C16.6
HGNC (Hugo) HIST1H2BD
LocusID (NCBI) 3017
Atlas_Id 64291
Location 6p22.2  [Link to chromosome band 6p22]
Location_base_pair Starts at 26158121 and ends at 26158607 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HIST1H2BD (6p22.2) / HIST1H2BD (6p22.2)HIST1H2BD (6p22.2) / LRRC27 (10q26.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HIST1H2BD   4747
Cards
Entrez_Gene (NCBI)HIST1H2BD  3017  histone cluster 1 H2B family member d
AliasesH2B.1B; H2B/b; H2BFB; HIRIP2; 
dJ221C16.6
GeneCards (Weizmann)HIST1H2BD
Ensembl hg19 (Hinxton)ENSG00000158373 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000158373 [Gene_View]  chr6:26158121-26158607 [Contig_View]  HIST1H2BD [Vega]
ICGC DataPortalENSG00000158373
TCGA cBioPortalHIST1H2BD
AceView (NCBI)HIST1H2BD
Genatlas (Paris)HIST1H2BD
WikiGenes3017
SOURCE (Princeton)HIST1H2BD
Genetics Home Reference (NIH)HIST1H2BD
Genomic and cartography
GoldenPath hg38 (UCSC)HIST1H2BD  -     chr6:26158121-26158607 +  6p22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HIST1H2BD  -     6p22.2   [Description]    (hg19-Feb_2009)
EnsemblHIST1H2BD - 6p22.2 [CytoView hg19]  HIST1H2BD - 6p22.2 [CytoView hg38]
Mapping of homologs : NCBIHIST1H2BD [Mapview hg19]  HIST1H2BD [Mapview hg38]
OMIM602799   
Gene and transcription
Genbank (Entrez)AJ223353 AK292712 BC002842 BC096122 BE245851
RefSeq transcript (Entrez)NM_021063 NM_138720
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HIST1H2BD
Cluster EST : UnigeneHs.591797 [ NCBI ]
CGAP (NCI)Hs.591797
Alternative Splicing GalleryENSG00000158373
Gene ExpressionHIST1H2BD [ NCBI-GEO ]   HIST1H2BD [ EBI - ARRAY_EXPRESS ]   HIST1H2BD [ SEEK ]   HIST1H2BD [ MEM ]
Gene Expression Viewer (FireBrowse)HIST1H2BD [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3017
GTEX Portal (Tissue expression)HIST1H2BD
Human Protein AtlasENSG00000158373-HIST1H2BD [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP58876   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP58876  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP58876
Splice isoforms : SwissVarP58876
PhosPhoSitePlusP58876
Domaine pattern : Prosite (Expaxy)HISTONE_H2B (PS00357)   
Domains : Interpro (EBI)Histone-fold    Histone_H2A/H2B/H3    Histone_H2B   
Domain families : Pfam (Sanger)Histone (PF00125)   
Domain families : Pfam (NCBI)pfam00125   
Domain families : Smart (EMBL)H2B (SM00427)  
Conserved Domain (NCBI)HIST1H2BD
DMDM Disease mutations3017
Blocks (Seattle)HIST1H2BD
SuperfamilyP58876
Human Protein Atlas [tissue]ENSG00000158373-HIST1H2BD [tissue]
Peptide AtlasP58876
HPRD07535
IPIIPI00152906   IPI00930570   
Protein Interaction databases
DIP (DOE-UCLA)P58876
IntAct (EBI)P58876
FunCoupENSG00000158373
BioGRIDHIST1H2BD
STRING (EMBL)HIST1H2BD
ZODIACHIST1H2BD
Ontologies - Pathways
QuickGOP58876
Ontology : AmiGOnucleosome  molecular_function  DNA binding  nucleus  nucleoplasm  nucleoplasm  cytosol  nucleosome assembly  protein ubiquitination  protein heterodimerization activity  extracellular exosome  
Ontology : EGO-EBInucleosome  molecular_function  DNA binding  nucleus  nucleoplasm  nucleoplasm  cytosol  nucleosome assembly  protein ubiquitination  protein heterodimerization activity  extracellular exosome  
NDEx NetworkHIST1H2BD
Atlas of Cancer Signalling NetworkHIST1H2BD
Wikipedia pathwaysHIST1H2BD
Orthology - Evolution
OrthoDB3017
GeneTree (enSembl)ENSG00000158373
Phylogenetic Trees/Animal Genes : TreeFamHIST1H2BD
HOVERGENP58876
HOGENOMP58876
Homologs : HomoloGeneHIST1H2BD
Homology/Alignments : Family Browser (UCSC)HIST1H2BD
Gene fusions - Rearrangements
Fusion : QuiverHIST1H2BD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIST1H2BD [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIST1H2BD
dbVarHIST1H2BD
ClinVarHIST1H2BD
1000_GenomesHIST1H2BD 
Exome Variant ServerHIST1H2BD
ExAC (Exome Aggregation Consortium)ENSG00000158373
GNOMAD BrowserENSG00000158373
Genetic variants : HAPMAP3017
Genomic Variants (DGV)HIST1H2BD [DGVbeta]
DECIPHERHIST1H2BD [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHIST1H2BD 
Mutations
ICGC Data PortalHIST1H2BD 
TCGA Data PortalHIST1H2BD 
Broad Tumor PortalHIST1H2BD
OASIS PortalHIST1H2BD [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHIST1H2BD  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHIST1H2BD
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIST1H2BD
DgiDB (Drug Gene Interaction Database)HIST1H2BD
DoCM (Curated mutations)HIST1H2BD (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIST1H2BD (select a term)
intoGenHIST1H2BD
Cancer3DHIST1H2BD(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602799   
Orphanet
DisGeNETHIST1H2BD
MedgenHIST1H2BD
Genetic Testing Registry HIST1H2BD
NextProtP58876 [Medical]
TSGene3017
GENETestsHIST1H2BD
Target ValidationHIST1H2BD
Huge Navigator HIST1H2BD [HugePedia]
snp3D : Map Gene to Disease3017
BioCentury BCIQHIST1H2BD
ClinGenHIST1H2BD
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3017
Chemical/Pharm GKB GenePA29122
Clinical trialHIST1H2BD
Miscellaneous
canSAR (ICR)HIST1H2BD (select the gene name)
Probes
Litterature
PubMed1 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIST1H2BD
EVEXHIST1H2BD
GoPubMedHIST1H2BD
iHOPHIST1H2BD
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Feb 23 18:21:18 CET 2018

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