Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HIST1H2BJ (histone cluster 1 H2B family member j)

Identity

Other aliasH2B/r
H2BFR
H2BJ
HGNC (Hugo) HIST1H2BJ
LocusID (NCBI) 8970
Atlas_Id 56917
Location 6p22.1  [Link to chromosome band 6p22]
Location_base_pair Starts at 27132316 and ends at 27132796 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GTPBP2 (6p21.1) / HIST1H2BJ (6p22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(p21;p22) GTPBP2/HIST1H2BJ


External links

Nomenclature
HGNC (Hugo)HIST1H2BJ   4761
Cards
Entrez_Gene (NCBI)HIST1H2BJ  8970  histone cluster 1 H2B family member j
AliasesH2B/r; H2BFR; H2BJ
GeneCards (Weizmann)HIST1H2BJ
Ensembl hg19 (Hinxton)ENSG00000124635 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000124635 [Gene_View]  ENSG00000124635 [Sequence]  chr6:27132316-27132796 [Contig_View]  HIST1H2BJ [Vega]
ICGC DataPortalENSG00000124635
TCGA cBioPortalHIST1H2BJ
AceView (NCBI)HIST1H2BJ
Genatlas (Paris)HIST1H2BJ
WikiGenes8970
SOURCE (Princeton)HIST1H2BJ
Genetics Home Reference (NIH)HIST1H2BJ
Genomic and cartography
GoldenPath hg38 (UCSC)HIST1H2BJ  -     chr6:27132316-27132796 -  6p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HIST1H2BJ  -     6p22.1   [Description]    (hg19-Feb_2009)
EnsemblHIST1H2BJ - 6p22.1 [CytoView hg19]  HIST1H2BJ - 6p22.1 [CytoView hg38]
Mapping of homologs : NCBIHIST1H2BJ [Mapview hg19]  HIST1H2BJ [Mapview hg38]
OMIM615044   
Gene and transcription
Genbank (Entrez)AK311849 BC014312
RefSeq transcript (Entrez)NM_021058
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HIST1H2BJ
Cluster EST : UnigeneHs.656567 [ NCBI ]
CGAP (NCI)Hs.656567
Alternative Splicing GalleryENSG00000124635
Gene ExpressionHIST1H2BJ [ NCBI-GEO ]   HIST1H2BJ [ EBI - ARRAY_EXPRESS ]   HIST1H2BJ [ SEEK ]   HIST1H2BJ [ MEM ]
Gene Expression Viewer (FireBrowse)HIST1H2BJ [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8970
GTEX Portal (Tissue expression)HIST1H2BJ
Human Protein AtlasENSG00000124635-HIST1H2BJ [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP06899   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP06899  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP06899
Splice isoforms : SwissVarP06899
PhosPhoSitePlusP06899
Domaine pattern : Prosite (Expaxy)HISTONE_H2B (PS00357)   
Domains : Interpro (EBI)Histone-fold    Histone_H2A/H2B/H3    Histone_H2B   
Domain families : Pfam (Sanger)Histone (PF00125)   
Domain families : Pfam (NCBI)pfam00125   
Domain families : Smart (EMBL)H2B (SM00427)  
Conserved Domain (NCBI)HIST1H2BJ
DMDM Disease mutations8970
Blocks (Seattle)HIST1H2BJ
PDB (SRS)2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WA9    3WAA    3WTP    4CAY    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5CPI    5CPJ    5CPK    5FUG    5GSE    5GTC    5GXQ    5JRG    5VEY    5X7X    5XF3    5XF4    5XF5    6BUZ   
PDB (PDBSum)2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WA9    3WAA    3WTP    4CAY    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5CPI    5CPJ    5CPK    5FUG    5GSE    5GTC    5GXQ    5JRG    5VEY    5X7X    5XF3    5XF4    5XF5    6BUZ   
PDB (IMB)2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WA9    3WAA    3WTP    4CAY    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5CPI    5CPJ    5CPK    5FUG    5GSE    5GTC    5GXQ    5JRG    5VEY    5X7X    5XF3    5XF4    5XF5    6BUZ   
PDB (RSDB)2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WA9    3WAA    3WTP    4CAY    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5CPI    5CPJ    5CPK    5FUG    5GSE    5GTC    5GXQ    5JRG    5VEY    5X7X    5XF3    5XF4    5XF5    6BUZ   
Structural Biology KnowledgeBase2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WA9    3WAA    3WTP    4CAY    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5CPI    5CPJ    5CPK    5FUG    5GSE    5GTC    5GXQ    5JRG    5VEY    5X7X    5XF3    5XF4    5XF5    6BUZ   
SCOP (Structural Classification of Proteins)2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WA9    3WAA    3WTP    4CAY    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5CPI    5CPJ    5CPK    5FUG    5GSE    5GTC    5GXQ    5JRG    5VEY    5X7X    5XF3    5XF4    5XF5    6BUZ   
CATH (Classification of proteins structures)2RVQ    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3W96    3W97    3W98    3W99    3WA9    3WAA    3WTP    4CAY    4YM5    4YM6    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5CPI    5CPJ    5CPK    5FUG    5GSE    5GTC    5GXQ    5JRG    5VEY    5X7X    5XF3    5XF4    5XF5    6BUZ   
SuperfamilyP06899
Human Protein Atlas [tissue]ENSG00000124635-HIST1H2BJ [tissue]
Peptide AtlasP06899
IPIIPI00515061   
Protein Interaction databases
DIP (DOE-UCLA)P06899
IntAct (EBI)P06899
FunCoupENSG00000124635
BioGRIDHIST1H2BJ
STRING (EMBL)HIST1H2BJ
ZODIACHIST1H2BJ
Ontologies - Pathways
QuickGOP06899
Ontology : AmiGOnucleosome  lipopolysaccharide binding  innate immune response in mucosa  DNA binding  DNA binding  protein binding  extracellular space  nucleus  nucleus  nucleoplasm  nucleoplasm  cytosol  plasma membrane  nucleosome assembly  nucleosome assembly  negative regulation of tumor necrosis factor-mediated signaling pathway  protein ubiquitination  antibacterial humoral response  killing of cells of other organism  protein heterodimerization activity  defense response to Gram-negative bacterium  defense response to Gram-positive bacterium  antimicrobial humoral immune response mediated by antimicrobial peptide  
Ontology : EGO-EBInucleosome  lipopolysaccharide binding  innate immune response in mucosa  DNA binding  DNA binding  protein binding  extracellular space  nucleus  nucleus  nucleoplasm  nucleoplasm  cytosol  plasma membrane  nucleosome assembly  nucleosome assembly  negative regulation of tumor necrosis factor-mediated signaling pathway  protein ubiquitination  antibacterial humoral response  killing of cells of other organism  protein heterodimerization activity  defense response to Gram-negative bacterium  defense response to Gram-positive bacterium  antimicrobial humoral immune response mediated by antimicrobial peptide  
Pathways : KEGGAlcoholism    Viral carcinogenesis    Systemic lupus erythematosus   
NDEx NetworkHIST1H2BJ
Atlas of Cancer Signalling NetworkHIST1H2BJ
Wikipedia pathwaysHIST1H2BJ
Orthology - Evolution
OrthoDB8970
GeneTree (enSembl)ENSG00000124635
Phylogenetic Trees/Animal Genes : TreeFamHIST1H2BJ
HOVERGENP06899
HOGENOMP06899
Homologs : HomoloGeneHIST1H2BJ
Homology/Alignments : Family Browser (UCSC)HIST1H2BJ
Gene fusions - Rearrangements
Fusion : QuiverHIST1H2BJ
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIST1H2BJ [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIST1H2BJ
dbVarHIST1H2BJ
ClinVarHIST1H2BJ
1000_GenomesHIST1H2BJ 
Exome Variant ServerHIST1H2BJ
ExAC (Exome Aggregation Consortium)ENSG00000124635
GNOMAD BrowserENSG00000124635
Varsome BrowserHIST1H2BJ
Genetic variants : HAPMAP8970
Genomic Variants (DGV)HIST1H2BJ [DGVbeta]
DECIPHERHIST1H2BJ [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHIST1H2BJ 
Mutations
ICGC Data PortalHIST1H2BJ 
TCGA Data PortalHIST1H2BJ 
Broad Tumor PortalHIST1H2BJ
OASIS PortalHIST1H2BJ [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHIST1H2BJ  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHIST1H2BJ
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIST1H2BJ
DgiDB (Drug Gene Interaction Database)HIST1H2BJ
DoCM (Curated mutations)HIST1H2BJ (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIST1H2BJ (select a term)
intoGenHIST1H2BJ
Cancer3DHIST1H2BJ(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615044   
Orphanet
DisGeNETHIST1H2BJ
MedgenHIST1H2BJ
Genetic Testing Registry HIST1H2BJ
NextProtP06899 [Medical]
TSGene8970
GENETestsHIST1H2BJ
Target ValidationHIST1H2BJ
Huge Navigator HIST1H2BJ [HugePedia]
snp3D : Map Gene to Disease8970
BioCentury BCIQHIST1H2BJ
ClinGenHIST1H2BJ
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8970
Chemical/Pharm GKB GenePA29136
Clinical trialHIST1H2BJ
Miscellaneous
canSAR (ICR)HIST1H2BJ (select the gene name)
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIST1H2BJ
EVEXHIST1H2BJ
GoPubMedHIST1H2BJ
iHOPHIST1H2BJ
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:10:53 CET 2018

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