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HIST1H2BO (histone cluster 1 H2B family member o)

Identity

Alias_namesH2BFN
H2B histone family, member N
histone 1, H2bo
histone cluster 1, H2bo
Alias_symbol (synonym)H2B/n
H2B.2
Other aliasdJ193B12.2
HGNC (Hugo) HIST1H2BO
LocusID (NCBI) 8348
Atlas_Id 64302
Location 6p22.1  [Link to chromosome band 6p22]
Location_base_pair Starts at 27893425 and ends at 27893891 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HIST1H2BO   4758
Cards
Entrez_Gene (NCBI)HIST1H2BO  8348  histone cluster 1 H2B family member o
AliasesH2B.2; H2B/n; H2BFN; dJ193B12.2
GeneCards (Weizmann)HIST1H2BO
Ensembl hg19 (Hinxton)ENSG00000274641 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000274641 [Gene_View]  chr6:27893425-27893891 [Contig_View]  HIST1H2BO [Vega]
ICGC DataPortalENSG00000274641
TCGA cBioPortalHIST1H2BO
AceView (NCBI)HIST1H2BO
Genatlas (Paris)HIST1H2BO
WikiGenes8348
SOURCE (Princeton)HIST1H2BO
Genetics Home Reference (NIH)HIST1H2BO
Genomic and cartography
GoldenPath hg38 (UCSC)HIST1H2BO  -     chr6:27893425-27893891 +  6p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HIST1H2BO  -     6p22.1   [Description]    (hg19-Feb_2009)
EnsemblHIST1H2BO - 6p22.1 [CytoView hg19]  HIST1H2BO - 6p22.1 [CytoView hg38]
Mapping of homologs : NCBIHIST1H2BO [Mapview hg19]  HIST1H2BO [Mapview hg38]
OMIM602808   
Gene and transcription
Genbank (Entrez)BC106720 BX647290 EU446972
RefSeq transcript (Entrez)NM_003527
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HIST1H2BO
Cluster EST : UnigeneHs.484991 [ NCBI ]
CGAP (NCI)Hs.484991
Alternative Splicing GalleryENSG00000274641
Gene ExpressionHIST1H2BO [ NCBI-GEO ]   HIST1H2BO [ EBI - ARRAY_EXPRESS ]   HIST1H2BO [ SEEK ]   HIST1H2BO [ MEM ]
Gene Expression Viewer (FireBrowse)HIST1H2BO [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8348
GTEX Portal (Tissue expression)HIST1H2BO
Human Protein AtlasENSG00000274641-HIST1H2BO [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP23527   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP23527  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP23527
Splice isoforms : SwissVarP23527
PhosPhoSitePlusP23527
Domaine pattern : Prosite (Expaxy)HISTONE_H2B (PS00357)   
Domains : Interpro (EBI)Histone-fold    Histone_H2A/H2B/H3    Histone_H2B   
Domain families : Pfam (Sanger)Histone (PF00125)   
Domain families : Pfam (NCBI)pfam00125   
Domain families : Smart (EMBL)H2B (SM00427)  
Conserved Domain (NCBI)HIST1H2BO
DMDM Disease mutations8348
Blocks (Seattle)HIST1H2BO
SuperfamilyP23527
Human Protein Atlas [tissue]ENSG00000274641-HIST1H2BO [tissue]
Peptide AtlasP23527
HPRD11904
IPIIPI00152785   
Protein Interaction databases
DIP (DOE-UCLA)P23527
IntAct (EBI)P23527
FunCoupENSG00000274641
BioGRIDHIST1H2BO
STRING (EMBL)HIST1H2BO
ZODIACHIST1H2BO
Ontologies - Pathways
QuickGOP23527
Ontology : AmiGOnucleosome  DNA binding  DNA binding  nucleus  nucleoplasm  nucleoplasm  cytosol  nucleosome assembly  nucleosome assembly  protein ubiquitination  protein heterodimerization activity  
Ontology : EGO-EBInucleosome  DNA binding  DNA binding  nucleus  nucleoplasm  nucleoplasm  cytosol  nucleosome assembly  nucleosome assembly  protein ubiquitination  protein heterodimerization activity  
NDEx NetworkHIST1H2BO
Atlas of Cancer Signalling NetworkHIST1H2BO
Wikipedia pathwaysHIST1H2BO
Orthology - Evolution
OrthoDB8348
GeneTree (enSembl)ENSG00000274641
Phylogenetic Trees/Animal Genes : TreeFamHIST1H2BO
HOVERGENP23527
HOGENOMP23527
Homologs : HomoloGeneHIST1H2BO
Homology/Alignments : Family Browser (UCSC)HIST1H2BO
Gene fusions - Rearrangements
Fusion : QuiverHIST1H2BO
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIST1H2BO [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIST1H2BO
dbVarHIST1H2BO
ClinVarHIST1H2BO
1000_GenomesHIST1H2BO 
Exome Variant ServerHIST1H2BO
ExAC (Exome Aggregation Consortium)ENSG00000274641
GNOMAD BrowserENSG00000274641
Genetic variants : HAPMAP8348
Genomic Variants (DGV)HIST1H2BO [DGVbeta]
DECIPHERHIST1H2BO [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHIST1H2BO 
Mutations
ICGC Data PortalHIST1H2BO 
TCGA Data PortalHIST1H2BO 
Broad Tumor PortalHIST1H2BO
OASIS PortalHIST1H2BO [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDHIST1H2BO
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIST1H2BO
DgiDB (Drug Gene Interaction Database)HIST1H2BO
DoCM (Curated mutations)HIST1H2BO (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIST1H2BO (select a term)
intoGenHIST1H2BO
Cancer3DHIST1H2BO(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602808   
Orphanet
DisGeNETHIST1H2BO
MedgenHIST1H2BO
Genetic Testing Registry HIST1H2BO
NextProtP23527 [Medical]
TSGene8348
GENETestsHIST1H2BO
Target ValidationHIST1H2BO
Huge Navigator HIST1H2BO [HugePedia]
snp3D : Map Gene to Disease8348
BioCentury BCIQHIST1H2BO
ClinGenHIST1H2BO
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8348
Chemical/Pharm GKB GenePA29133
Clinical trialHIST1H2BO
Miscellaneous
canSAR (ICR)HIST1H2BO (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIST1H2BO
EVEXHIST1H2BO
GoPubMedHIST1H2BO
iHOPHIST1H2BO
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Feb 23 18:21:19 CET 2018

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