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HIST1H3C (histone cluster 1 H3 family member c)

Identity

Alias_namesH3FC
H3 histone family, member C
histone 1, H3c
histone cluster 1, H3c
Alias_symbol (synonym)H3/c
H3.1
Other alias
HGNC (Hugo) HIST1H3C
LocusID (NCBI) 8352
Atlas_Id 64304
Location 6p22.2  [Link to chromosome band 6p22]
Location_base_pair Starts at 26045411 and ends at 26045869 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HIST1H3C   4768
Cards
Entrez_Gene (NCBI)HIST1H3C  8352  histone cluster 1 H3 family member c
AliasesH3.1; H3/c; H3FC
GeneCards (Weizmann)HIST1H3C
Ensembl hg19 (Hinxton)ENSG00000278272 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000278272 [Gene_View]  ENSG00000278272 [Sequence]  chr6:26045411-26045869 [Contig_View]  HIST1H3C [Vega]
ICGC DataPortalENSG00000278272
TCGA cBioPortalHIST1H3C
AceView (NCBI)HIST1H3C
Genatlas (Paris)HIST1H3C
WikiGenes8352
SOURCE (Princeton)HIST1H3C
Genetics Home Reference (NIH)HIST1H3C
Genomic and cartography
GoldenPath hg38 (UCSC)HIST1H3C  -     chr6:26045411-26045869 +  6p22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HIST1H3C  -     6p22.2   [Description]    (hg19-Feb_2009)
HIST1H3C - 6p22.2 [CytoView hg19]  HIST1H3C - 6p22.2 [CytoView hg38]
Mapping of homologs : NCBIHIST1H3C [Mapview hg19]  HIST1H3C [Mapview hg38]
OMIM602812   
Gene and transcription
Genbank (Entrez)BC058834 BC127610 BC160079
RefSeq transcript (Entrez)NM_003531
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HIST1H3C
Cluster EST : UnigeneHs.248176 [ NCBI ]
CGAP (NCI)Hs.248176
Alternative Splicing GalleryENSG00000278272
Gene ExpressionHIST1H3C [ NCBI-GEO ]   HIST1H3C [ EBI - ARRAY_EXPRESS ]   HIST1H3C [ SEEK ]   HIST1H3C [ MEM ]
Gene Expression Viewer (FireBrowse)HIST1H3C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8352
GTEX Portal (Tissue expression)HIST1H3C
Human Protein AtlasENSG00000278272-HIST1H3C [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP68431   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP68431  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP68431
Splice isoforms : SwissVarP68431
PhosPhoSitePlusP68431
Domaine pattern : Prosite (Expaxy)HISTONE_H3_1 (PS00322)    HISTONE_H3_2 (PS00959)   
Domains : Interpro (EBI)Histone-fold    Histone_H2A/H2B/H3    Histone_H3/CENP-A   
Domain families : Pfam (Sanger)Histone (PF00125)   
Domain families : Pfam (NCBI)pfam00125   
Domain families : Smart (EMBL)H3 (SM00428)  
Conserved Domain (NCBI)HIST1H3C
DMDM Disease mutations8352
Blocks (Seattle)HIST1H3C
PDB (RSDB)1CS9    1CT6    1O9S    1Q3L    2B2T    2B2U    2B2V    2B2W    2C1J    2C1N    2CV5    2KWJ    2KWK    2L75    2LBM    2M0O    2NDF    2NDG    2OQ6    2OT7    2OX0    2RI7    2UXN    2VPG    2X0L    3A1B    3AFA    3AVR    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3B95    3KMT    3KQI    3LQI    3LQJ    3O34    3O35    3O37    3QJ6    3RIG    3RIY    3SOU    3SOW    3U31    3U3D    3U4S    3U5N    3U5O    3U5P    3UEE    3UEF    3UIG    3UII    3UIK    3V43    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3X1S    3X1T    3X1U    3X1V    3ZG6    3ZVY    4A0J    4A0N    4A7J    4BD3    4C1Q    4F4U    4F56    4FWF    4HON    4I51    4L7X    4LK9    4LKA    4LLB    4LXL    4N4H    4QBQ    4QBR    4QBS    4TN7    4U68    4UP0    4UY4    4X3K    4YHP    4YHZ    4YM5    4YM6    4Z0R    4Z2M    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5B24    5B2I    5B2J    5B31    5C11    5C13    5C3I    5CH1    5CH2    5CPI    5CPJ    5CPK    5D6Y    5DAH    5FB0    5FB1    5FFV    5HJB    5HJC    5HJD    5HYN    5IQL    5J3V    5JHN    5JIN    5JIY    5JJ0    5SVX    5SVY    5T0K    5T0M    5T1G    5T1I    5TBN    5TDR    5TDW   
PDB Europe1CS9    1CT6    1O9S    1Q3L    2B2T    2B2U    2B2V    2B2W    2C1J    2C1N    2CV5    2KWJ    2KWK    2L75    2LBM    2M0O    2NDF    2NDG    2OQ6    2OT7    2OX0    2RI7    2UXN    2VPG    2X0L    3A1B    3AFA    3AVR    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3B95    3KMT    3KQI    3LQI    3LQJ    3O34    3O35    3O37    3QJ6    3RIG    3RIY    3SOU    3SOW    3U31    3U3D    3U4S    3U5N    3U5O    3U5P    3UEE    3UEF    3UIG    3UII    3UIK    3V43    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3X1S    3X1T    3X1U    3X1V    3ZG6    3ZVY    4A0J    4A0N    4A7J    4BD3    4C1Q    4F4U    4F56    4FWF    4HON    4I51    4L7X    4LK9    4LKA    4LLB    4LXL    4N4H    4QBQ    4QBR    4QBS    4TN7    4U68    4UP0    4UY4    4X3K    4YHP    4YHZ    4YM5    4YM6    4Z0R    4Z2M    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5B24    5B2I    5B2J    5B31    5C11    5C13    5C3I    5CH1    5CH2    5CPI    5CPJ    5CPK    5D6Y    5DAH    5FB0    5FB1    5FFV    5HJB    5HJC    5HJD    5HYN    5IQL    5J3V    5JHN    5JIN    5JIY    5JJ0    5SVX    5SVY    5T0K    5T0M    5T1G    5T1I    5TBN    5TDR    5TDW   
PDB (PDBSum)1CS9    1CT6    1O9S    1Q3L    2B2T    2B2U    2B2V    2B2W    2C1J    2C1N    2CV5    2KWJ    2KWK    2L75    2LBM    2M0O    2NDF    2NDG    2OQ6    2OT7    2OX0    2RI7    2UXN    2VPG    2X0L    3A1B    3AFA    3AVR    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3B95    3KMT    3KQI    3LQI    3LQJ    3O34    3O35    3O37    3QJ6    3RIG    3RIY    3SOU    3SOW    3U31    3U3D    3U4S    3U5N    3U5O    3U5P    3UEE    3UEF    3UIG    3UII    3UIK    3V43    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3X1S    3X1T    3X1U    3X1V    3ZG6    3ZVY    4A0J    4A0N    4A7J    4BD3    4C1Q    4F4U    4F56    4FWF    4HON    4I51    4L7X    4LK9    4LKA    4LLB    4LXL    4N4H    4QBQ    4QBR    4QBS    4TN7    4U68    4UP0    4UY4    4X3K    4YHP    4YHZ    4YM5    4YM6    4Z0R    4Z2M    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5B24    5B2I    5B2J    5B31    5C11    5C13    5C3I    5CH1    5CH2    5CPI    5CPJ    5CPK    5D6Y    5DAH    5FB0    5FB1    5FFV    5HJB    5HJC    5HJD    5HYN    5IQL    5J3V    5JHN    5JIN    5JIY    5JJ0    5SVX    5SVY    5T0K    5T0M    5T1G    5T1I    5TBN    5TDR    5TDW   
PDB (IMB)1CS9    1CT6    1O9S    1Q3L    2B2T    2B2U    2B2V    2B2W    2C1J    2C1N    2CV5    2KWJ    2KWK    2L75    2LBM    2M0O    2NDF    2NDG    2OQ6    2OT7    2OX0    2RI7    2UXN    2VPG    2X0L    3A1B    3AFA    3AVR    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3B95    3KMT    3KQI    3LQI    3LQJ    3O34    3O35    3O37    3QJ6    3RIG    3RIY    3SOU    3SOW    3U31    3U3D    3U4S    3U5N    3U5O    3U5P    3UEE    3UEF    3UIG    3UII    3UIK    3V43    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3X1S    3X1T    3X1U    3X1V    3ZG6    3ZVY    4A0J    4A0N    4A7J    4BD3    4C1Q    4F4U    4F56    4FWF    4HON    4I51    4L7X    4LK9    4LKA    4LLB    4LXL    4N4H    4QBQ    4QBR    4QBS    4TN7    4U68    4UP0    4UY4    4X3K    4YHP    4YHZ    4YM5    4YM6    4Z0R    4Z2M    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5B24    5B2I    5B2J    5B31    5C11    5C13    5C3I    5CH1    5CH2    5CPI    5CPJ    5CPK    5D6Y    5DAH    5FB0    5FB1    5FFV    5HJB    5HJC    5HJD    5HYN    5IQL    5J3V    5JHN    5JIN    5JIY    5JJ0    5SVX    5SVY    5T0K    5T0M    5T1G    5T1I    5TBN    5TDR    5TDW   
Structural Biology KnowledgeBase1CS9    1CT6    1O9S    1Q3L    2B2T    2B2U    2B2V    2B2W    2C1J    2C1N    2CV5    2KWJ    2KWK    2L75    2LBM    2M0O    2NDF    2NDG    2OQ6    2OT7    2OX0    2RI7    2UXN    2VPG    2X0L    3A1B    3AFA    3AVR    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3B95    3KMT    3KQI    3LQI    3LQJ    3O34    3O35    3O37    3QJ6    3RIG    3RIY    3SOU    3SOW    3U31    3U3D    3U4S    3U5N    3U5O    3U5P    3UEE    3UEF    3UIG    3UII    3UIK    3V43    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3X1S    3X1T    3X1U    3X1V    3ZG6    3ZVY    4A0J    4A0N    4A7J    4BD3    4C1Q    4F4U    4F56    4FWF    4HON    4I51    4L7X    4LK9    4LKA    4LLB    4LXL    4N4H    4QBQ    4QBR    4QBS    4TN7    4U68    4UP0    4UY4    4X3K    4YHP    4YHZ    4YM5    4YM6    4Z0R    4Z2M    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5B24    5B2I    5B2J    5B31    5C11    5C13    5C3I    5CH1    5CH2    5CPI    5CPJ    5CPK    5D6Y    5DAH    5FB0    5FB1    5FFV    5HJB    5HJC    5HJD    5HYN    5IQL    5J3V    5JHN    5JIN    5JIY    5JJ0    5SVX    5SVY    5T0K    5T0M    5T1G    5T1I    5TBN    5TDR    5TDW   
SCOP (Structural Classification of Proteins)1CS9    1CT6    1O9S    1Q3L    2B2T    2B2U    2B2V    2B2W    2C1J    2C1N    2CV5    2KWJ    2KWK    2L75    2LBM    2M0O    2NDF    2NDG    2OQ6    2OT7    2OX0    2RI7    2UXN    2VPG    2X0L    3A1B    3AFA    3AVR    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3B95    3KMT    3KQI    3LQI    3LQJ    3O34    3O35    3O37    3QJ6    3RIG    3RIY    3SOU    3SOW    3U31    3U3D    3U4S    3U5N    3U5O    3U5P    3UEE    3UEF    3UIG    3UII    3UIK    3V43    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3X1S    3X1T    3X1U    3X1V    3ZG6    3ZVY    4A0J    4A0N    4A7J    4BD3    4C1Q    4F4U    4F56    4FWF    4HON    4I51    4L7X    4LK9    4LKA    4LLB    4LXL    4N4H    4QBQ    4QBR    4QBS    4TN7    4U68    4UP0    4UY4    4X3K    4YHP    4YHZ    4YM5    4YM6    4Z0R    4Z2M    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5B24    5B2I    5B2J    5B31    5C11    5C13    5C3I    5CH1    5CH2    5CPI    5CPJ    5CPK    5D6Y    5DAH    5FB0    5FB1    5FFV    5HJB    5HJC    5HJD    5HYN    5IQL    5J3V    5JHN    5JIN    5JIY    5JJ0    5SVX    5SVY    5T0K    5T0M    5T1G    5T1I    5TBN    5TDR    5TDW   
CATH (Classification of proteins structures)1CS9    1CT6    1O9S    1Q3L    2B2T    2B2U    2B2V    2B2W    2C1J    2C1N    2CV5    2KWJ    2KWK    2L75    2LBM    2M0O    2NDF    2NDG    2OQ6    2OT7    2OX0    2RI7    2UXN    2VPG    2X0L    3A1B    3AFA    3AVR    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3B95    3KMT    3KQI    3LQI    3LQJ    3O34    3O35    3O37    3QJ6    3RIG    3RIY    3SOU    3SOW    3U31    3U3D    3U4S    3U5N    3U5O    3U5P    3UEE    3UEF    3UIG    3UII    3UIK    3V43    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3X1S    3X1T    3X1U    3X1V    3ZG6    3ZVY    4A0J    4A0N    4A7J    4BD3    4C1Q    4F4U    4F56    4FWF    4HON    4I51    4L7X    4LK9    4LKA    4LLB    4LXL    4N4H    4QBQ    4QBR    4QBS    4TN7    4U68    4UP0    4UY4    4X3K    4YHP    4YHZ    4YM5    4YM6    4Z0R    4Z2M    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5B24    5B2I    5B2J    5B31    5C11    5C13    5C3I    5CH1    5CH2    5CPI    5CPJ    5CPK    5D6Y    5DAH    5FB0    5FB1    5FFV    5HJB    5HJC    5HJD    5HYN    5IQL    5J3V    5JHN    5JIN    5JIY    5JJ0    5SVX    5SVY    5T0K    5T0M    5T1G    5T1I    5TBN    5TDR    5TDW   
SuperfamilyP68431
Human Protein Atlas [tissue]ENSG00000278272-HIST1H3C [tissue]
Peptide AtlasP68431
HPRD11906
Protein Interaction databases
DIP (DOE-UCLA)P68431
IntAct (EBI)P68431
FunCoupENSG00000278272
BioGRIDHIST1H3C
STRING (EMBL)HIST1H3C
ZODIACHIST1H3C
Ontologies - Pathways
QuickGOP68431
Ontology : AmiGOchromatin silencing at rDNA  nuclear chromosome  nuclear chromosome, telomeric region  nucleosome  nuclear nucleosome  DNA binding  protein binding  extracellular region  nucleus  nucleoplasm  chromatin organization  nucleosome assembly  nucleosome assembly  DNA replication-dependent nucleosome assembly  blood coagulation  membrane  gene silencing by RNA  telomere organization  histone binding  protein complex  cellular protein metabolic process  cadherin binding  negative regulation of gene expression, epigenetic  positive regulation of gene expression, epigenetic  protein heterodimerization activity  protein heterotetramerization  regulation of gene silencing  extracellular exosome  
Ontology : EGO-EBIchromatin silencing at rDNA  nuclear chromosome  nuclear chromosome, telomeric region  nucleosome  nuclear nucleosome  DNA binding  protein binding  extracellular region  nucleus  nucleoplasm  chromatin organization  nucleosome assembly  nucleosome assembly  DNA replication-dependent nucleosome assembly  blood coagulation  membrane  gene silencing by RNA  telomere organization  histone binding  protein complex  cellular protein metabolic process  cadherin binding  negative regulation of gene expression, epigenetic  positive regulation of gene expression, epigenetic  protein heterodimerization activity  protein heterotetramerization  regulation of gene silencing  extracellular exosome  
NDEx NetworkHIST1H3C
Atlas of Cancer Signalling NetworkHIST1H3C
Wikipedia pathwaysHIST1H3C
Orthology - Evolution
OrthoDB8352
GeneTree (enSembl)ENSG00000278272
Phylogenetic Trees/Animal Genes : TreeFamHIST1H3C
HOGENOMP68431
Homologs : HomoloGeneHIST1H3C
Homology/Alignments : Family Browser (UCSC)HIST1H3C
Gene fusions - Rearrangements
Fusion : QuiverHIST1H3C
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIST1H3C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIST1H3C
dbVarHIST1H3C
ClinVarHIST1H3C
1000_GenomesHIST1H3C 
Exome Variant ServerHIST1H3C
ExAC (Exome Aggregation Consortium)ENSG00000278272
GNOMAD BrowserENSG00000278272
Varsome BrowserHIST1H3C
Genetic variants : HAPMAP8352
Genomic Variants (DGV)HIST1H3C [DGVbeta]
DECIPHERHIST1H3C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHIST1H3C 
Mutations
ICGC Data PortalHIST1H3C 
TCGA Data PortalHIST1H3C 
Broad Tumor PortalHIST1H3C
OASIS PortalHIST1H3C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHIST1H3C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHIST1H3C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIST1H3C
DgiDB (Drug Gene Interaction Database)HIST1H3C
DoCM (Curated mutations)HIST1H3C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIST1H3C (select a term)
intoGenHIST1H3C
Cancer3DHIST1H3C(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602812   
Orphanet
DisGeNETHIST1H3C
MedgenHIST1H3C
Genetic Testing Registry HIST1H3C
NextProtP68431 [Medical]
TSGene8352
GENETestsHIST1H3C
Target ValidationHIST1H3C
Huge Navigator HIST1H3C [HugePedia]
snp3D : Map Gene to Disease8352
BioCentury BCIQHIST1H3C
ClinGenHIST1H3C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8352
Chemical/Pharm GKB GenePA29143
Clinical trialHIST1H3C
Miscellaneous
canSAR (ICR)HIST1H3C (select the gene name)
DataMed IndexHIST1H3C
Probes
Litterature
PubMed62 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIST1H3C
EVEXHIST1H3C
GoPubMedHIST1H3C
iHOPHIST1H3C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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