Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

HIST1H4B (histone cluster 1 H4 family member b)

Identity

Alias_namesH4FI
H4 histone family, member I
histone 1, H4b
histone cluster 1, H4b
Alias_symbol (synonym)H4/I
Other alias
HGNC (Hugo) HIST1H4B
LocusID (NCBI) 8366
Atlas_Id 55456
Location 6p22.2  [Link to chromosome band 6p22]
Location_base_pair Starts at 26026896 and ends at 26027252 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(p22;p22) HIST1H4E/HIST1H4B


External links

Nomenclature
HGNC (Hugo)HIST1H4B   4789
Cards
Entrez_Gene (NCBI)HIST1H4B  8366  histone cluster 1 H4 family member b
AliasesH4/I; H4FI
GeneCards (Weizmann)HIST1H4B
Ensembl hg19 (Hinxton)ENSG00000278705 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000278705 [Gene_View]  ENSG00000278705 [Sequence]  chr6:26026896-26027252 [Contig_View]  HIST1H4B [Vega]
ICGC DataPortalENSG00000278705
TCGA cBioPortalHIST1H4B
AceView (NCBI)HIST1H4B
Genatlas (Paris)HIST1H4B
WikiGenes8366
SOURCE (Princeton)HIST1H4B
Genetics Home Reference (NIH)HIST1H4B
Genomic and cartography
GoldenPath hg38 (UCSC)HIST1H4B  -     chr6:26026896-26027252 -  6p22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HIST1H4B  -     6p22.2   [Description]    (hg19-Feb_2009)
EnsemblHIST1H4B - 6p22.2 [CytoView hg19]  HIST1H4B - 6p22.2 [CytoView hg38]
Mapping of homologs : NCBIHIST1H4B [Mapview hg19]  HIST1H4B [Mapview hg38]
OMIM602829   
Gene and transcription
Genbank (Entrez)BC069467
RefSeq transcript (Entrez)NM_003544
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HIST1H4B
Cluster EST : UnigeneHs.143080 [ NCBI ]
CGAP (NCI)Hs.143080
Alternative Splicing GalleryENSG00000278705
Gene ExpressionHIST1H4B [ NCBI-GEO ]   HIST1H4B [ EBI - ARRAY_EXPRESS ]   HIST1H4B [ SEEK ]   HIST1H4B [ MEM ]
Gene Expression Viewer (FireBrowse)HIST1H4B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8366
GTEX Portal (Tissue expression)HIST1H4B
Human Protein AtlasENSG00000278705-HIST1H4B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62805   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62805  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62805
Splice isoforms : SwissVarP62805
PhosPhoSitePlusP62805
Domaine pattern : Prosite (Expaxy)HISTONE_H4 (PS00047)   
Domains : Interpro (EBI)Histone-fold    Histone_H4    Histone_H4_CS    TAF_TATA-bd   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)H4 (SM00417)  TAF (SM00803)  
Conserved Domain (NCBI)HIST1H4B
DMDM Disease mutations8366
Blocks (Seattle)HIST1H4B
PDB (SRS)1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5JA4    5KDM   
PDB (PDBSum)1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5JA4    5KDM   
PDB (IMB)1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5JA4    5KDM   
PDB (RSDB)1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5JA4    5KDM   
Structural Biology KnowledgeBase1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5JA4    5KDM   
SCOP (Structural Classification of Proteins)1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5JA4    5KDM   
CATH (Classification of proteins structures)1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5JA4    5KDM   
SuperfamilyP62805
Human Protein Atlas [tissue]ENSG00000278705-HIST1H4B [tissue]
Peptide AtlasP62805
HPRD11920
Protein Interaction databases
DIP (DOE-UCLA)P62805
IntAct (EBI)P62805
FunCoupENSG00000278705
BioGRIDHIST1H4B
STRING (EMBL)HIST1H4B
ZODIACHIST1H4B
Ontologies - Pathways
QuickGOP62805
Ontology : AmiGOchromatin silencing at rDNA  nuclear chromosome  nuclear chromosome, telomeric region  nucleosome  nucleosome  nuclear nucleosome  nuclear nucleosome  DNA binding  DNA binding  RNA binding  protein binding  extracellular region  nucleus  nucleus  nucleoplasm  double-strand break repair via nonhomologous end joining  nucleosome assembly  nucleosome assembly  DNA replication-dependent nucleosome assembly  DNA replication-independent nucleosome assembly  DNA-templated transcription, initiation  membrane  telomere capping  protein domain specific binding  extracellular matrix  telomere organization  CENP-A containing nucleosome assembly  histone binding  protein complex  cellular protein metabolic process  regulation of megakaryocyte differentiation  negative regulation of megakaryocyte differentiation  negative regulation of gene expression, epigenetic  positive regulation of gene expression, epigenetic  protein heterodimerization activity  protein heterotetramerization  regulation of gene silencing by miRNA  extracellular exosome  regulation of hematopoietic stem cell differentiation  beta-catenin-TCF complex assembly  
Ontology : EGO-EBIchromatin silencing at rDNA  nuclear chromosome  nuclear chromosome, telomeric region  nucleosome  nucleosome  nuclear nucleosome  nuclear nucleosome  DNA binding  DNA binding  RNA binding  protein binding  extracellular region  nucleus  nucleus  nucleoplasm  double-strand break repair via nonhomologous end joining  nucleosome assembly  nucleosome assembly  DNA replication-dependent nucleosome assembly  DNA replication-independent nucleosome assembly  DNA-templated transcription, initiation  membrane  telomere capping  protein domain specific binding  extracellular matrix  telomere organization  CENP-A containing nucleosome assembly  histone binding  protein complex  cellular protein metabolic process  regulation of megakaryocyte differentiation  negative regulation of megakaryocyte differentiation  negative regulation of gene expression, epigenetic  positive regulation of gene expression, epigenetic  protein heterodimerization activity  protein heterotetramerization  regulation of gene silencing by miRNA  extracellular exosome  regulation of hematopoietic stem cell differentiation  beta-catenin-TCF complex assembly  
NDEx NetworkHIST1H4B
Atlas of Cancer Signalling NetworkHIST1H4B
Wikipedia pathwaysHIST1H4B
Orthology - Evolution
OrthoDB8366
GeneTree (enSembl)ENSG00000278705
Phylogenetic Trees/Animal Genes : TreeFamHIST1H4B
HOVERGENP62805
HOGENOMP62805
Homologs : HomoloGeneHIST1H4B
Homology/Alignments : Family Browser (UCSC)HIST1H4B
Gene fusions - Rearrangements
Fusion : QuiverHIST1H4B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIST1H4B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIST1H4B
dbVarHIST1H4B
ClinVarHIST1H4B
1000_GenomesHIST1H4B 
Exome Variant ServerHIST1H4B
ExAC (Exome Aggregation Consortium)ENSG00000278705
GNOMAD BrowserENSG00000278705
Genetic variants : HAPMAP8366
Genomic Variants (DGV)HIST1H4B [DGVbeta]
DECIPHERHIST1H4B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHIST1H4B 
Mutations
ICGC Data PortalHIST1H4B 
TCGA Data PortalHIST1H4B 
Broad Tumor PortalHIST1H4B
OASIS PortalHIST1H4B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHIST1H4B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHIST1H4B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIST1H4B
DgiDB (Drug Gene Interaction Database)HIST1H4B
DoCM (Curated mutations)HIST1H4B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIST1H4B (select a term)
intoGenHIST1H4B
Cancer3DHIST1H4B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602829   
Orphanet
DisGeNETHIST1H4B
MedgenHIST1H4B
Genetic Testing Registry HIST1H4B
NextProtP62805 [Medical]
TSGene8366
GENETestsHIST1H4B
Target ValidationHIST1H4B
Huge Navigator HIST1H4B [HugePedia]
snp3D : Map Gene to Disease8366
BioCentury BCIQHIST1H4B
ClinGenHIST1H4B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8366
Chemical/Pharm GKB GenePA29164
Clinical trialHIST1H4B
Miscellaneous
canSAR (ICR)HIST1H4B (select the gene name)
Probes
Litterature
PubMed90 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIST1H4B
EVEXHIST1H4B
GoPubMedHIST1H4B
iHOPHIST1H4B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 22 16:29:04 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.