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HIST1H4H (histone cluster 1 H4 family member h)

Identity

Alias_namesH4FH
H4 histone family, member H
histone 1, H4h
histone cluster 1, H4h
Alias_symbol (synonym)H4/h
Other alias
HGNC (Hugo) HIST1H4H
LocusID (NCBI) 8365
Atlas_Id 55480
Location 6p22.2  [Link to chromosome band 6p22]
Location_base_pair Starts at 26285126 and ends at 26285499 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HIST1H4H   4788
Cards
Entrez_Gene (NCBI)HIST1H4H  8365  histone cluster 1 H4 family member h
AliasesH4/h; H4FH
GeneCards (Weizmann)HIST1H4H
Ensembl hg19 (Hinxton)ENSG00000158406 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000158406 [Gene_View]  ENSG00000158406 [Sequence]  chr6:26285126-26285499 [Contig_View]  HIST1H4H [Vega]
ICGC DataPortalENSG00000158406
TCGA cBioPortalHIST1H4H
AceView (NCBI)HIST1H4H
Genatlas (Paris)HIST1H4H
WikiGenes8365
SOURCE (Princeton)HIST1H4H
Genetics Home Reference (NIH)HIST1H4H
Genomic and cartography
GoldenPath hg38 (UCSC)HIST1H4H  -     chr6:26285126-26285499 -  6p22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HIST1H4H  -     6p22.2   [Description]    (hg19-Feb_2009)
EnsemblHIST1H4H - 6p22.2 [CytoView hg19]  HIST1H4H - 6p22.2 [CytoView hg38]
Mapping of homologs : NCBIHIST1H4H [Mapview hg19]  HIST1H4H [Mapview hg38]
OMIM602828   
Gene and transcription
Genbank (Entrez)BC010926 BC120939 CR542169 CR542187
RefSeq transcript (Entrez)NM_003543
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HIST1H4H
Cluster EST : UnigeneHs.591790 [ NCBI ]
CGAP (NCI)Hs.591790
Alternative Splicing GalleryENSG00000158406
Gene ExpressionHIST1H4H [ NCBI-GEO ]   HIST1H4H [ EBI - ARRAY_EXPRESS ]   HIST1H4H [ SEEK ]   HIST1H4H [ MEM ]
Gene Expression Viewer (FireBrowse)HIST1H4H [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8365
GTEX Portal (Tissue expression)HIST1H4H
Human Protein AtlasENSG00000158406-HIST1H4H [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62805   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62805  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62805
Splice isoforms : SwissVarP62805
PhosPhoSitePlusP62805
Domaine pattern : Prosite (Expaxy)HISTONE_H4 (PS00047)   
Domains : Interpro (EBI)Histone-fold    Histone_H4    Histone_H4_CS    TAF_TATA-bd   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)H4 (SM00417)  TAF (SM00803)  
Conserved Domain (NCBI)HIST1H4H
DMDM Disease mutations8365
Blocks (Seattle)HIST1H4H
PDB (SRS)1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5JA4    5KDM   
PDB (PDBSum)1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5JA4    5KDM   
PDB (IMB)1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5JA4    5KDM   
PDB (RSDB)1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5JA4    5KDM   
Structural Biology KnowledgeBase1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5JA4    5KDM   
SCOP (Structural Classification of Proteins)1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5JA4    5KDM   
CATH (Classification of proteins structures)1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5JA4    5KDM   
SuperfamilyP62805
Human Protein Atlas [tissue]ENSG00000158406-HIST1H4H [tissue]
Peptide AtlasP62805
HPRD11919
Protein Interaction databases
DIP (DOE-UCLA)P62805
IntAct (EBI)P62805
FunCoupENSG00000158406
BioGRIDHIST1H4H
STRING (EMBL)HIST1H4H
ZODIACHIST1H4H
Ontologies - Pathways
QuickGOP62805
Ontology : AmiGOchromatin silencing at rDNA  nuclear chromosome  nuclear chromosome, telomeric region  nucleosome  nucleosome  nuclear nucleosome  nuclear nucleosome  DNA binding  DNA binding  RNA binding  protein binding  extracellular region  nucleus  nucleus  nucleoplasm  double-strand break repair via nonhomologous end joining  nucleosome assembly  nucleosome assembly  DNA replication-dependent nucleosome assembly  DNA replication-independent nucleosome assembly  DNA-templated transcription, initiation  membrane  telomere capping  protein domain specific binding  extracellular matrix  telomere organization  CENP-A containing nucleosome assembly  histone binding  protein complex  cellular protein metabolic process  regulation of megakaryocyte differentiation  negative regulation of megakaryocyte differentiation  negative regulation of gene expression, epigenetic  positive regulation of gene expression, epigenetic  protein heterodimerization activity  protein heterotetramerization  regulation of gene silencing by miRNA  extracellular exosome  regulation of hematopoietic stem cell differentiation  beta-catenin-TCF complex assembly  
Ontology : EGO-EBIchromatin silencing at rDNA  nuclear chromosome  nuclear chromosome, telomeric region  nucleosome  nucleosome  nuclear nucleosome  nuclear nucleosome  DNA binding  DNA binding  RNA binding  protein binding  extracellular region  nucleus  nucleus  nucleoplasm  double-strand break repair via nonhomologous end joining  nucleosome assembly  nucleosome assembly  DNA replication-dependent nucleosome assembly  DNA replication-independent nucleosome assembly  DNA-templated transcription, initiation  membrane  telomere capping  protein domain specific binding  extracellular matrix  telomere organization  CENP-A containing nucleosome assembly  histone binding  protein complex  cellular protein metabolic process  regulation of megakaryocyte differentiation  negative regulation of megakaryocyte differentiation  negative regulation of gene expression, epigenetic  positive regulation of gene expression, epigenetic  protein heterodimerization activity  protein heterotetramerization  regulation of gene silencing by miRNA  extracellular exosome  regulation of hematopoietic stem cell differentiation  beta-catenin-TCF complex assembly  
NDEx NetworkHIST1H4H
Atlas of Cancer Signalling NetworkHIST1H4H
Wikipedia pathwaysHIST1H4H
Orthology - Evolution
OrthoDB8365
GeneTree (enSembl)ENSG00000158406
Phylogenetic Trees/Animal Genes : TreeFamHIST1H4H
HOVERGENP62805
HOGENOMP62805
Homologs : HomoloGeneHIST1H4H
Homology/Alignments : Family Browser (UCSC)HIST1H4H
Gene fusions - Rearrangements
Fusion : QuiverHIST1H4H
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIST1H4H [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIST1H4H
dbVarHIST1H4H
ClinVarHIST1H4H
1000_GenomesHIST1H4H 
Exome Variant ServerHIST1H4H
ExAC (Exome Aggregation Consortium)ENSG00000158406
GNOMAD BrowserENSG00000158406
Genetic variants : HAPMAP8365
Genomic Variants (DGV)HIST1H4H [DGVbeta]
DECIPHERHIST1H4H [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHIST1H4H 
Mutations
ICGC Data PortalHIST1H4H 
TCGA Data PortalHIST1H4H 
Broad Tumor PortalHIST1H4H
OASIS PortalHIST1H4H [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHIST1H4H  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHIST1H4H
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIST1H4H
DgiDB (Drug Gene Interaction Database)HIST1H4H
DoCM (Curated mutations)HIST1H4H (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIST1H4H (select a term)
intoGenHIST1H4H
Cancer3DHIST1H4H(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602828   
Orphanet
DisGeNETHIST1H4H
MedgenHIST1H4H
Genetic Testing Registry HIST1H4H
NextProtP62805 [Medical]
TSGene8365
GENETestsHIST1H4H
Target ValidationHIST1H4H
Huge Navigator HIST1H4H [HugePedia]
snp3D : Map Gene to Disease8365
BioCentury BCIQHIST1H4H
ClinGenHIST1H4H
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8365
Chemical/Pharm GKB GenePA29163
Clinical trialHIST1H4H
Miscellaneous
canSAR (ICR)HIST1H4H (select the gene name)
Probes
Litterature
PubMed88 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIST1H4H
EVEXHIST1H4H
GoPubMedHIST1H4H
iHOPHIST1H4H
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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