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HIST1H4K (histone cluster 1 H4 family member k)

Identity

Alias_namesH4FD
H4 histone family, member D
histone 1, H4k
histone cluster 1, H4k
Alias_symbol (synonym)H4/d
H4F2iii
dJ160A22.1
Other alias
HGNC (Hugo) HIST1H4K
LocusID (NCBI) 8362
Atlas_Id 53716
Location 6p22.1  [Link to chromosome band 6p22]
Location_base_pair Starts at 27831174 and ends at 27831527 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HIST1H4K   4784
Cards
Entrez_Gene (NCBI)HIST1H4K  8362  histone cluster 1 H4 family member k
AliasesH4/d; H4F2iii; H4FD; dJ160A22.1
GeneCards (Weizmann)HIST1H4K
Ensembl hg19 (Hinxton)ENSG00000273542 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000273542 [Gene_View]  ENSG00000273542 [Sequence]  chr6:27831174-27831527 [Contig_View]  HIST1H4K [Vega]
ICGC DataPortalENSG00000273542
TCGA cBioPortalHIST1H4K
AceView (NCBI)HIST1H4K
Genatlas (Paris)HIST1H4K
WikiGenes8362
SOURCE (Princeton)HIST1H4K
Genetics Home Reference (NIH)HIST1H4K
Genomic and cartography
GoldenPath hg38 (UCSC)HIST1H4K  -     chr6:27831174-27831527 -  6p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HIST1H4K  -     6p22.1   [Description]    (hg19-Feb_2009)
EnsemblHIST1H4K - 6p22.1 [CytoView hg19]  HIST1H4K - 6p22.1 [CytoView hg38]
Mapping of homologs : NCBIHIST1H4K [Mapview hg19]  HIST1H4K [Mapview hg38]
OMIM602825   
Gene and transcription
Genbank (Entrez)AK312028
RefSeq transcript (Entrez)NM_003541
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HIST1H4K
Cluster EST : UnigeneHs.528055 [ NCBI ]
CGAP (NCI)Hs.528055
Alternative Splicing GalleryENSG00000273542
Gene ExpressionHIST1H4K [ NCBI-GEO ]   HIST1H4K [ EBI - ARRAY_EXPRESS ]   HIST1H4K [ SEEK ]   HIST1H4K [ MEM ]
Gene Expression Viewer (FireBrowse)HIST1H4K [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8362
GTEX Portal (Tissue expression)HIST1H4K
Human Protein AtlasENSG00000273542-HIST1H4K [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62805   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62805  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62805
Splice isoforms : SwissVarP62805
PhosPhoSitePlusP62805
Domaine pattern : Prosite (Expaxy)HISTONE_H4 (PS00047)   
Domains : Interpro (EBI)CENP-T/H4_C    Histone-fold    Histone_H4    Histone_H4_CS    TAF_TATA-bd   
Domain families : Pfam (Sanger)CENP-T_C (PF15511)   
Domain families : Pfam (NCBI)pfam15511   
Domain families : Smart (EMBL)H4 (SM00417)  TAF (SM00803)  
Conserved Domain (NCBI)HIST1H4K
DMDM Disease mutations8362
Blocks (Seattle)HIST1H4K
PDB (SRS)1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5GSE    5GSU    5GT0    5GT3    5GTC    5GXQ    5JA4    5JRG    5KDM    5TEG    5X7X    5XF3    5XF4    5XF5    6BUZ    6C0W   
PDB (PDBSum)1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5GSE    5GSU    5GT0    5GT3    5GTC    5GXQ    5JA4    5JRG    5KDM    5TEG    5X7X    5XF3    5XF4    5XF5    6BUZ    6C0W   
PDB (IMB)1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5GSE    5GSU    5GT0    5GT3    5GTC    5GXQ    5JA4    5JRG    5KDM    5TEG    5X7X    5XF3    5XF4    5XF5    6BUZ    6C0W   
PDB (RSDB)1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5GSE    5GSU    5GT0    5GT3    5GTC    5GXQ    5JA4    5JRG    5KDM    5TEG    5X7X    5XF3    5XF4    5XF5    6BUZ    6C0W   
Structural Biology KnowledgeBase1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5GSE    5GSU    5GT0    5GT3    5GTC    5GXQ    5JA4    5JRG    5KDM    5TEG    5X7X    5XF3    5XF4    5XF5    6BUZ    6C0W   
SCOP (Structural Classification of Proteins)1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5GSE    5GSU    5GT0    5GT3    5GTC    5GXQ    5JA4    5JRG    5KDM    5TEG    5X7X    5XF3    5XF4    5XF5    6BUZ    6C0W   
CATH (Classification of proteins structures)1ZKK    2BQZ    2CV5    2IG0    2KWN    2KWO    2LVM    2QQS    2RJE    2RNY    2RS9    3A6N    3AFA    3AN2    3AV1    3AV2    3AYW    3AZE    3AZF    3AZG    3AZH    3AZI    3AZJ    3AZK    3AZL    3AZM    3AZN    3CFS    3CFV    3F9W    3F9X    3F9Y    3F9Z    3IJ1    3JPX    3NQJ    3NQU    3O36    3QBY    3QZS    3QZT    3QZV    3R45    3UVW    3UVX    3UVY    3UW9    3W96    3W97    3W98    3W99    3WA9    3WAA    3WKJ    3WTP    3X1S    3X1T    3X1U    3X1V    4GQB    4H9N    4H9O    4H9P    4H9Q    4H9R    4H9S    4HGA    4M38    4N3W    4N4F    4QUT    4QUU    4QYD    4U9W    4YM5    4YM6    4YY6    4YYD    4YYG    4YYH    4YYI    4YYJ    4YYK    4YYM    4YYN    4Z2M    4Z5T    5AV5    5AV6    5AV8    5AV9    5AVB    5AVC    5AY8    5B0Y    5B0Z    5B24    5B2I    5B2J    5B31    5B32    5B33    5B40    5BNV    5BNX    5BO0    5C3I    5CPI    5CPJ    5CPK    5FA5    5FFW    5FWE    5GSE    5GSU    5GT0    5GT3    5GTC    5GXQ    5JA4    5JRG    5KDM    5TEG    5X7X    5XF3    5XF4    5XF5    6BUZ    6C0W   
SuperfamilyP62805
Human Protein Atlas [tissue]ENSG00000273542-HIST1H4K [tissue]
Peptide AtlasP62805
HPRD11916
Protein Interaction databases
DIP (DOE-UCLA)P62805
IntAct (EBI)P62805
FunCoupENSG00000273542
BioGRIDHIST1H4K
STRING (EMBL)HIST1H4K
ZODIACHIST1H4K
Ontologies - Pathways
QuickGOP62805
Ontology : AmiGOchromatin silencing at rDNA  nuclear chromosome  nuclear chromosome, telomeric region  nucleosome  nucleosome  nuclear nucleosome  DNA binding  RNA binding  protein binding  extracellular region  nucleus  nucleus  nucleoplasm  double-strand break repair via nonhomologous end joining  nucleosome assembly  DNA replication-dependent nucleosome assembly  DNA replication-independent nucleosome assembly  DNA-templated transcription, initiation  membrane  telomere capping  protein domain specific binding  telomere organization  protein-containing complex  CENP-A containing nucleosome assembly  cellular protein metabolic process  regulation of megakaryocyte differentiation  negative regulation of megakaryocyte differentiation  negative regulation of gene expression, epigenetic  protein heterodimerization activity  protein heterotetramerization  regulation of gene silencing by miRNA  extracellular exosome  
Ontology : EGO-EBIchromatin silencing at rDNA  nuclear chromosome  nuclear chromosome, telomeric region  nucleosome  nucleosome  nuclear nucleosome  DNA binding  RNA binding  protein binding  extracellular region  nucleus  nucleus  nucleoplasm  double-strand break repair via nonhomologous end joining  nucleosome assembly  DNA replication-dependent nucleosome assembly  DNA replication-independent nucleosome assembly  DNA-templated transcription, initiation  membrane  telomere capping  protein domain specific binding  telomere organization  protein-containing complex  CENP-A containing nucleosome assembly  cellular protein metabolic process  regulation of megakaryocyte differentiation  negative regulation of megakaryocyte differentiation  negative regulation of gene expression, epigenetic  protein heterodimerization activity  protein heterotetramerization  regulation of gene silencing by miRNA  extracellular exosome  
Pathways : KEGGAlcoholism    Viral carcinogenesis    Systemic lupus erythematosus   
NDEx NetworkHIST1H4K
Atlas of Cancer Signalling NetworkHIST1H4K
Wikipedia pathwaysHIST1H4K
Orthology - Evolution
OrthoDB8362
GeneTree (enSembl)ENSG00000273542
Phylogenetic Trees/Animal Genes : TreeFamHIST1H4K
HOVERGENP62805
HOGENOMP62805
Homologs : HomoloGeneHIST1H4K
Homology/Alignments : Family Browser (UCSC)HIST1H4K
Gene fusions - Rearrangements
Fusion : QuiverHIST1H4K
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIST1H4K [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIST1H4K
dbVarHIST1H4K
ClinVarHIST1H4K
1000_GenomesHIST1H4K 
Exome Variant ServerHIST1H4K
ExAC (Exome Aggregation Consortium)ENSG00000273542
GNOMAD BrowserENSG00000273542
Varsome BrowserHIST1H4K
Genetic variants : HAPMAP8362
Genomic Variants (DGV)HIST1H4K [DGVbeta]
DECIPHERHIST1H4K [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHIST1H4K 
Mutations
ICGC Data PortalHIST1H4K 
TCGA Data PortalHIST1H4K 
Broad Tumor PortalHIST1H4K
OASIS PortalHIST1H4K [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHIST1H4K  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHIST1H4K
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIST1H4K
DgiDB (Drug Gene Interaction Database)HIST1H4K
DoCM (Curated mutations)HIST1H4K (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIST1H4K (select a term)
intoGenHIST1H4K
Cancer3DHIST1H4K(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602825   
Orphanet
DisGeNETHIST1H4K
MedgenHIST1H4K
Genetic Testing Registry HIST1H4K
NextProtP62805 [Medical]
TSGene8362
GENETestsHIST1H4K
Target ValidationHIST1H4K
Huge Navigator HIST1H4K [HugePedia]
snp3D : Map Gene to Disease8362
BioCentury BCIQHIST1H4K
ClinGenHIST1H4K
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8362
Chemical/Pharm GKB GenePA29159
Clinical trialHIST1H4K
Miscellaneous
canSAR (ICR)HIST1H4K (select the gene name)
Probes
Litterature
PubMed86 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIST1H4K
EVEXHIST1H4K
GoPubMedHIST1H4K
iHOPHIST1H4K
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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