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HIST2H2BE (histone cluster 2, H2be)

Identity

Alias_namesH2B
H2BFQ
H2B histone family, member Q
histone 2, H2be
histone cluster 2, H2be
Alias_symbol (synonym)H2B/q
H2B.1
Other aliasGL105
H2BGL105
H2BQ
HGNC (Hugo) HIST2H2BE
LocusID (NCBI) 8349
Atlas_Id 52876
Location 1q21.2  [Link to chromosome band 1q21]
Location_base_pair Starts at 149856010 and ends at 149858232 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
HIST2H2BE (1q21.2) / CAPZA1 (1p13.2)HIST2H2BE (1q21.2) / PFDN6 (6p21.32)HIST2H2BE (1q21.2) / RNF26 (11q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HIST2H2BE   4760
Cards
Entrez_Gene (NCBI)HIST2H2BE  8349  histone cluster 2, H2be
AliasesGL105; H2B; H2B.1; H2BFQ; 
H2BGL105; H2BQ
GeneCards (Weizmann)HIST2H2BE
Ensembl hg19 (Hinxton)ENSG00000184678 [Gene_View]  chr1:149856010-149858232 [Contig_View]  HIST2H2BE [Vega]
Ensembl hg38 (Hinxton)ENSG00000184678 [Gene_View]  chr1:149856010-149858232 [Contig_View]  HIST2H2BE [Vega]
ICGC DataPortalENSG00000184678
TCGA cBioPortalHIST2H2BE
AceView (NCBI)HIST2H2BE
Genatlas (Paris)HIST2H2BE
WikiGenes8349
SOURCE (Princeton)HIST2H2BE
Genetics Home Reference (NIH)HIST2H2BE
Genomic and cartography
GoldenPath hg19 (UCSC)HIST2H2BE  -     chr1:149856010-149858232 -  1q21.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)HIST2H2BE  -     1q21.2   [Description]    (hg38-Dec_2013)
EnsemblHIST2H2BE - 1q21.2 [CytoView hg19]  HIST2H2BE - 1q21.2 [CytoView hg38]
Mapping of homologs : NCBIHIST2H2BE [Mapview hg19]  HIST2H2BE [Mapview hg38]
OMIM601831   
Gene and transcription
Genbank (Entrez)AK093747 AK289725 BC005827 BC069193 BC096121
RefSeq transcript (Entrez)NM_003528
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_004487 NW_004929293
Consensus coding sequences : CCDS (NCBI)HIST2H2BE
Cluster EST : UnigeneHs.2178 [ NCBI ]
CGAP (NCI)Hs.2178
Alternative Splicing GalleryENSG00000184678
Gene ExpressionHIST2H2BE [ NCBI-GEO ]   HIST2H2BE [ EBI - ARRAY_EXPRESS ]   HIST2H2BE [ SEEK ]   HIST2H2BE [ MEM ]
Gene Expression Viewer (FireBrowse)HIST2H2BE [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8349
GTEX Portal (Tissue expression)HIST2H2BE
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16778   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16778  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16778
Splice isoforms : SwissVarQ16778
PhosPhoSitePlusQ16778
Domaine pattern : Prosite (Expaxy)HISTONE_H2B (PS00357)   
Domains : Interpro (EBI)Histone-fold    Histone_H2A/H2B/H3    Histone_H2B   
Domain families : Pfam (Sanger)Histone (PF00125)   
Domain families : Pfam (NCBI)pfam00125   
Domain families : Smart (EMBL)H2B (SM00427)  
Conserved Domain (NCBI)HIST2H2BE
DMDM Disease mutations8349
Blocks (Seattle)HIST2H2BE
PDB (SRS)4NFT   
PDB (PDBSum)4NFT   
PDB (IMB)4NFT   
PDB (RSDB)4NFT   
Structural Biology KnowledgeBase4NFT   
SCOP (Structural Classification of Proteins)4NFT   
CATH (Classification of proteins structures)4NFT   
SuperfamilyQ16778
Human Protein AtlasENSG00000184678
Peptide AtlasQ16778
HPRD03494
IPIIPI00003935   
Protein Interaction databases
DIP (DOE-UCLA)Q16778
IntAct (EBI)Q16778
FunCoupENSG00000184678
BioGRIDHIST2H2BE
STRING (EMBL)HIST2H2BE
ZODIACHIST2H2BE
Ontologies - Pathways
QuickGOQ16778
Ontology : AmiGOnucleosome  nuclear nucleosome  innate immune response in mucosa  DNA binding  DNA binding  extracellular space  nucleus  nucleoplasm  nucleoplasm  cytoplasm  nucleosome assembly  nucleosome assembly  antibacterial humoral response  protein heterodimerization activity  defense response to Gram-positive bacterium  extracellular exosome  
Ontology : EGO-EBInucleosome  nuclear nucleosome  innate immune response in mucosa  DNA binding  DNA binding  extracellular space  nucleus  nucleoplasm  nucleoplasm  cytoplasm  nucleosome assembly  nucleosome assembly  antibacterial humoral response  protein heterodimerization activity  defense response to Gram-positive bacterium  extracellular exosome  
Pathways : KEGGAlcoholism    Viral carcinogenesis    Systemic lupus erythematosus   
NDEx NetworkHIST2H2BE
Atlas of Cancer Signalling NetworkHIST2H2BE
Wikipedia pathwaysHIST2H2BE
Orthology - Evolution
OrthoDB8349
GeneTree (enSembl)ENSG00000184678
Phylogenetic Trees/Animal Genes : TreeFamHIST2H2BE
HOVERGENQ16778
HOGENOMQ16778
Homologs : HomoloGeneHIST2H2BE
Homology/Alignments : Family Browser (UCSC)HIST2H2BE
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIST2H2BE [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIST2H2BE
dbVarHIST2H2BE
ClinVarHIST2H2BE
1000_GenomesHIST2H2BE 
Exome Variant ServerHIST2H2BE
ExAC (Exome Aggregation Consortium)HIST2H2BE (select the gene name)
Genetic variants : HAPMAP8349
Genomic Variants (DGV)HIST2H2BE [DGVbeta]
DECIPHER (Syndromes)1:149856010-149858232  ENSG00000184678
CONAN: Copy Number AnalysisHIST2H2BE 
Mutations
ICGC Data PortalHIST2H2BE 
TCGA Data PortalHIST2H2BE 
Broad Tumor PortalHIST2H2BE
OASIS PortalHIST2H2BE [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHIST2H2BE  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHIST2H2BE
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIST2H2BE
DgiDB (Drug Gene Interaction Database)HIST2H2BE
DoCM (Curated mutations)HIST2H2BE (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIST2H2BE (select a term)
intoGenHIST2H2BE
Cancer3DHIST2H2BE(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601831   
Orphanet
MedgenHIST2H2BE
Genetic Testing Registry HIST2H2BE
NextProtQ16778 [Medical]
TSGene8349
GENETestsHIST2H2BE
Huge Navigator HIST2H2BE [HugePedia]
snp3D : Map Gene to Disease8349
BioCentury BCIQHIST2H2BE
ClinGenHIST2H2BE
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8349
Chemical/Pharm GKB GenePA29135
Clinical trialHIST2H2BE
Miscellaneous
canSAR (ICR)HIST2H2BE (select the gene name)
Probes
Litterature
PubMed155 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIST2H2BE
EVEXHIST2H2BE
GoPubMedHIST2H2BE
iHOPHIST2H2BE
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:03:50 CEST 2017

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