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HIST2H3A (histone cluster 2 H3 family member a)

Identity

Alias_nameshistone 2, H3a
histone cluster 2, H3a
Alias_symbol (synonym)H3/n
H3/o
Other alias
HGNC (Hugo) HIST2H3A
LocusID (NCBI) 333932
Atlas_Id 50056
Location 1q21.2  [Link to chromosome band 1q21]
Location_base_pair Starts at 149840687 and ends at 149841193 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HIST2H3A   20505
Cards
Entrez_Gene (NCBI)HIST2H3A  333932  histone cluster 2 H3 family member a
AliasesH3/n; H3/o
GeneCards (Weizmann)HIST2H3A
Ensembl hg19 (Hinxton)ENSG00000203852 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000203852 [Gene_View]  chr1:149840687-149841193 [Contig_View]  HIST2H3A [Vega]
ICGC DataPortalENSG00000203852
TCGA cBioPortalHIST2H3A
AceView (NCBI)HIST2H3A
Genatlas (Paris)HIST2H3A
WikiGenes333932
SOURCE (Princeton)HIST2H3A
Genetics Home Reference (NIH)HIST2H3A
Genomic and cartography
GoldenPath hg38 (UCSC)HIST2H3A  -     chr1:149840687-149841193 -  1q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HIST2H3A  -     1q21.2   [Description]    (hg19-Feb_2009)
EnsemblHIST2H3A - 1q21.2 [CytoView hg19]  HIST2H3A - 1q21.2 [CytoView hg38]
Mapping of homologs : NCBIHIST2H3A [Mapview hg19]  HIST2H3A [Mapview hg38]
Gene and transcription
Genbank (Entrez)BC015544 BC074969 BC130635 BC130637
RefSeq transcript (Entrez)NM_001005464
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HIST2H3A
Cluster EST : UnigeneHs.706618 [ NCBI ]
CGAP (NCI)Hs.706618
Alternative Splicing GalleryENSG00000203852
Gene ExpressionHIST2H3A [ NCBI-GEO ]   HIST2H3A [ EBI - ARRAY_EXPRESS ]   HIST2H3A [ SEEK ]   HIST2H3A [ MEM ]
Gene Expression Viewer (FireBrowse)HIST2H3A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)333932
GTEX Portal (Tissue expression)HIST2H3A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ71DI3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ71DI3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ71DI3
Splice isoforms : SwissVarQ71DI3
PhosPhoSitePlusQ71DI3
Domaine pattern : Prosite (Expaxy)HISTONE_H3_1 (PS00322)    HISTONE_H3_2 (PS00959)   
Domains : Interpro (EBI)Histone-fold    Histone_H2A/H2B/H3    Histone_H3/CENP-A   
Domain families : Pfam (Sanger)Histone (PF00125)   
Domain families : Pfam (NCBI)pfam00125   
Domain families : Smart (EMBL)H3 (SM00428)  
Conserved Domain (NCBI)HIST2H3A
DMDM Disease mutations333932
Blocks (Seattle)HIST2H3A
PDB (SRS)2IIJ    2X4W    2X4X    2X4Y    3AV1    3DB3    3MO8    3QO2    3R93    4MZF    4MZG    4MZH    4OUC    5B0Y    5B0Z    5B40    5BO0    5CIU   
PDB (PDBSum)2IIJ    2X4W    2X4X    2X4Y    3AV1    3DB3    3MO8    3QO2    3R93    4MZF    4MZG    4MZH    4OUC    5B0Y    5B0Z    5B40    5BO0    5CIU   
PDB (IMB)2IIJ    2X4W    2X4X    2X4Y    3AV1    3DB3    3MO8    3QO2    3R93    4MZF    4MZG    4MZH    4OUC    5B0Y    5B0Z    5B40    5BO0    5CIU   
PDB (RSDB)2IIJ    2X4W    2X4X    2X4Y    3AV1    3DB3    3MO8    3QO2    3R93    4MZF    4MZG    4MZH    4OUC    5B0Y    5B0Z    5B40    5BO0    5CIU   
Structural Biology KnowledgeBase2IIJ    2X4W    2X4X    2X4Y    3AV1    3DB3    3MO8    3QO2    3R93    4MZF    4MZG    4MZH    4OUC    5B0Y    5B0Z    5B40    5BO0    5CIU   
SCOP (Structural Classification of Proteins)2IIJ    2X4W    2X4X    2X4Y    3AV1    3DB3    3MO8    3QO2    3R93    4MZF    4MZG    4MZH    4OUC    5B0Y    5B0Z    5B40    5BO0    5CIU   
CATH (Classification of proteins structures)2IIJ    2X4W    2X4X    2X4Y    3AV1    3DB3    3MO8    3QO2    3R93    4MZF    4MZG    4MZH    4OUC    5B0Y    5B0Z    5B40    5BO0    5CIU   
SuperfamilyQ71DI3
Human Protein AtlasENSG00000203852
Peptide AtlasQ71DI3
HPRD13626
Protein Interaction databases
DIP (DOE-UCLA)Q71DI3
IntAct (EBI)Q71DI3
FunCoupENSG00000203852
BioGRIDHIST2H3A
STRING (EMBL)HIST2H3A
ZODIACHIST2H3A
Ontologies - Pathways
QuickGOQ71DI3
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  chromatin silencing at rDNA  nucleosome  DNA binding  chromatin binding  protein binding  extracellular region  nucleus  nucleoplasm  chromatin organization  nucleosome assembly  blood coagulation  gene silencing by RNA  histone binding  cellular protein metabolic process  negative regulation of gene expression, epigenetic  positive regulation of gene expression, epigenetic  protein heterodimerization activity  extracellular exosome  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  chromatin silencing at rDNA  nucleosome  DNA binding  chromatin binding  protein binding  extracellular region  nucleus  nucleoplasm  chromatin organization  nucleosome assembly  blood coagulation  gene silencing by RNA  histone binding  cellular protein metabolic process  negative regulation of gene expression, epigenetic  positive regulation of gene expression, epigenetic  protein heterodimerization activity  extracellular exosome  
Pathways : KEGGAlcoholism    Transcriptional misregulation in cancer    Systemic lupus erythematosus   
NDEx NetworkHIST2H3A
Atlas of Cancer Signalling NetworkHIST2H3A
Wikipedia pathwaysHIST2H3A
Orthology - Evolution
OrthoDB333932
GeneTree (enSembl)ENSG00000203852
Phylogenetic Trees/Animal Genes : TreeFamHIST2H3A
HOVERGENQ71DI3
HOGENOMQ71DI3
Homologs : HomoloGeneHIST2H3A
Homology/Alignments : Family Browser (UCSC)HIST2H3A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIST2H3A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIST2H3A
dbVarHIST2H3A
ClinVarHIST2H3A
1000_GenomesHIST2H3A 
Exome Variant ServerHIST2H3A
ExAC (Exome Aggregation Consortium)HIST2H3A (select the gene name)
Genetic variants : HAPMAP333932
Genomic Variants (DGV)HIST2H3A [DGVbeta]
DECIPHERHIST2H3A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHIST2H3A 
Mutations
ICGC Data PortalHIST2H3A 
TCGA Data PortalHIST2H3A 
Broad Tumor PortalHIST2H3A
OASIS PortalHIST2H3A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHIST2H3A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHIST2H3A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIST2H3A
DgiDB (Drug Gene Interaction Database)HIST2H3A
DoCM (Curated mutations)HIST2H3A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIST2H3A (select a term)
intoGenHIST2H3A
Cancer3DHIST2H3A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenHIST2H3A
Genetic Testing Registry HIST2H3A
NextProtQ71DI3 [Medical]
TSGene333932
GENETestsHIST2H3A
Target ValidationHIST2H3A
Huge Navigator HIST2H3A [HugePedia]
snp3D : Map Gene to Disease333932
BioCentury BCIQHIST2H3A
ClinGenHIST2H3A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD333932
Chemical/Pharm GKB GenePA134926636
Clinical trialHIST2H3A
Miscellaneous
canSAR (ICR)HIST2H3A (select the gene name)
Probes
Litterature
PubMed65 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIST2H3A
EVEXHIST2H3A
GoPubMedHIST2H3A
iHOPHIST2H3A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:36:55 CEST 2017

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