Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HIST2H4B (histone cluster 2 H4 family member b)

Identity

Alias_nameshistone 2, H4b
histone cluster 2, H4b
Alias_symbol (synonym)H4/o
Other alias
HGNC (Hugo) HIST2H4B
LocusID (NCBI) 554313
Atlas_Id 55495
Location 1q21.2  [Link to chromosome band 1q21]
Location_base_pair Starts at 149832657 and ends at 149833052 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HIST2H4B   29607
Cards
Entrez_Gene (NCBI)HIST2H4B  554313  histone cluster 2 H4 family member b
AliasesH4/o
GeneCards (Weizmann)HIST2H4B
Ensembl hg19 (Hinxton)ENSG00000270276 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000270276 [Gene_View]  chr1:149832657-149833052 [Contig_View]  HIST2H4B [Vega]
ICGC DataPortalENSG00000270276
TCGA cBioPortalHIST2H4B
AceView (NCBI)HIST2H4B
Genatlas (Paris)HIST2H4B
WikiGenes554313
SOURCE (Princeton)HIST2H4B
Genetics Home Reference (NIH)HIST2H4B
Genomic and cartography
GoldenPath hg38 (UCSC)HIST2H4B  -     chr1:149832657-149833052 +  1q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HIST2H4B  -     1q21.2   [Description]    (hg19-Feb_2009)
EnsemblHIST2H4B - 1q21.2 [CytoView hg19]  HIST2H4B - 1q21.2 [CytoView hg38]
Mapping of homologs : NCBIHIST2H4B [Mapview hg19]  HIST2H4B [Mapview hg38]
Gene and transcription
Genbank (Entrez)BC019846 BC093969 BC108260 BC112193 CR542172
RefSeq transcript (Entrez)NM_001034077
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HIST2H4B
Cluster EST : UnigeneHs.706635 [ NCBI ]
CGAP (NCI)Hs.706635
Alternative Splicing GalleryENSG00000270276
Gene ExpressionHIST2H4B [ NCBI-GEO ]   HIST2H4B [ EBI - ARRAY_EXPRESS ]   HIST2H4B [ SEEK ]   HIST2H4B [ MEM ]
Gene Expression Viewer (FireBrowse)HIST2H4B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)554313
GTEX Portal (Tissue expression)HIST2H4B
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62805   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62805  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62805
Splice isoforms : SwissVarP62805
PhosPhoSitePlusP62805
Domaine pattern : Prosite (Expaxy)HISTONE_H4 (PS00047)   
Domains : Interpro (EBI)Histone-fold    Histone_H4    Histone_H4_CS    TAF_TATA-bd   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)H4 (SM00417)  TAF (SM00803)  
Conserved Domain (NCBI)HIST2H4B
DMDM Disease mutations554313
Blocks (Seattle)HIST2H4B
PDB (SRS)###############################################################################################################################################################################################################################################################   
PDB (PDBSum)###############################################################################################################################################################################################################################################################   
PDB (IMB)###############################################################################################################################################################################################################################################################   
PDB (RSDB)###############################################################################################################################################################################################################################################################   
Structural Biology KnowledgeBase###############################################################################################################################################################################################################################################################   
SCOP (Structural Classification of Proteins)###############################################################################################################################################################################################################################################################   
CATH (Classification of proteins structures)###############################################################################################################################################################################################################################################################   
SuperfamilyP62805
Human Protein AtlasENSG00000270276
Peptide AtlasP62805
IPIIPI00453473   IPI01013176   
Protein Interaction databases
DIP (DOE-UCLA)P62805
IntAct (EBI)P62805
FunCoupENSG00000270276
BioGRIDHIST2H4B
STRING (EMBL)HIST2H4B
ZODIACHIST2H4B
Ontologies - Pathways
QuickGOP62805
Ontology : AmiGOchromatin silencing at rDNA  nuclear chromosome  nuclear chromosome, telomeric region  nucleosome  nucleosome  nuclear nucleosome  DNA binding  DNA binding  RNA binding  protein binding  extracellular region  nucleus  nucleoplasm  double-strand break repair via nonhomologous end joining  nucleosome assembly  nucleosome assembly  DNA replication-dependent nucleosome assembly  DNA replication-independent nucleosome assembly  DNA-templated transcription, initiation  membrane  telomere capping  protein domain specific binding  extracellular matrix  gene silencing by RNA  telomere organization  CENP-A containing nucleosome assembly  histone binding  histone binding  protein complex  cellular protein metabolic process  negative regulation of megakaryocyte differentiation  negative regulation of gene expression, epigenetic  positive regulation of gene expression, epigenetic  protein heterodimerization activity  protein heterotetramerization  extracellular exosome  beta-catenin-TCF complex assembly  
Ontology : EGO-EBIchromatin silencing at rDNA  nuclear chromosome  nuclear chromosome, telomeric region  nucleosome  nucleosome  nuclear nucleosome  DNA binding  DNA binding  RNA binding  protein binding  extracellular region  nucleus  nucleoplasm  double-strand break repair via nonhomologous end joining  nucleosome assembly  nucleosome assembly  DNA replication-dependent nucleosome assembly  DNA replication-independent nucleosome assembly  DNA-templated transcription, initiation  membrane  telomere capping  protein domain specific binding  extracellular matrix  gene silencing by RNA  telomere organization  CENP-A containing nucleosome assembly  histone binding  histone binding  protein complex  cellular protein metabolic process  negative regulation of megakaryocyte differentiation  negative regulation of gene expression, epigenetic  positive regulation of gene expression, epigenetic  protein heterodimerization activity  protein heterotetramerization  extracellular exosome  beta-catenin-TCF complex assembly  
Pathways : KEGGAlcoholism    Viral carcinogenesis    Systemic lupus erythematosus   
NDEx NetworkHIST2H4B
Atlas of Cancer Signalling NetworkHIST2H4B
Wikipedia pathwaysHIST2H4B
Orthology - Evolution
OrthoDB554313
GeneTree (enSembl)ENSG00000270276
Phylogenetic Trees/Animal Genes : TreeFamHIST2H4B
HOVERGENP62805
HOGENOMP62805
Homologs : HomoloGeneHIST2H4B
Homology/Alignments : Family Browser (UCSC)HIST2H4B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIST2H4B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIST2H4B
dbVarHIST2H4B
ClinVarHIST2H4B
1000_GenomesHIST2H4B 
Exome Variant ServerHIST2H4B
ExAC (Exome Aggregation Consortium)HIST2H4B (select the gene name)
Genetic variants : HAPMAP554313
Genomic Variants (DGV)HIST2H4B [DGVbeta]
DECIPHERHIST2H4B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHIST2H4B 
Mutations
ICGC Data PortalHIST2H4B 
TCGA Data PortalHIST2H4B 
Broad Tumor PortalHIST2H4B
OASIS PortalHIST2H4B [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDHIST2H4B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIST2H4B
DgiDB (Drug Gene Interaction Database)HIST2H4B
DoCM (Curated mutations)HIST2H4B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIST2H4B (select a term)
intoGenHIST2H4B
Cancer3DHIST2H4B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenHIST2H4B
Genetic Testing Registry HIST2H4B
NextProtP62805 [Medical]
TSGene554313
GENETestsHIST2H4B
Target ValidationHIST2H4B
Huge Navigator HIST2H4B [HugePedia]
snp3D : Map Gene to Disease554313
BioCentury BCIQHIST2H4B
ClinGenHIST2H4B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD554313
Chemical/Pharm GKB GenePA145148733
Clinical trialHIST2H4B
Miscellaneous
canSAR (ICR)HIST2H4B (select the gene name)
Probes
Litterature
PubMed76 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIST2H4B
EVEXHIST2H4B
GoPubMedHIST2H4B
iHOPHIST2H4B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:36:56 CEST 2017

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