Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

HIST4H4 (histone cluster 4 H4)

Identity

Alias_nameshistone 4, H4
histone cluster 4, H4
Alias_symbol (synonym)MGC24116
Other aliasH4/p
HGNC (Hugo) HIST4H4
LocusID (NCBI) 121504
Atlas_Id 45565
Location 12p12.3  [Link to chromosome band 12p12]
Location_base_pair Starts at 14770720 and ends at 14771131 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HIST4H4   20510
Cards
Entrez_Gene (NCBI)HIST4H4  121504  histone cluster 4 H4
AliasesH4/p
GeneCards (Weizmann)HIST4H4
Ensembl hg19 (Hinxton)ENSG00000197837 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197837 [Gene_View]  chr12:14770720-14771131 [Contig_View]  HIST4H4 [Vega]
ICGC DataPortalENSG00000197837
TCGA cBioPortalHIST4H4
AceView (NCBI)HIST4H4
Genatlas (Paris)HIST4H4
WikiGenes121504
SOURCE (Princeton)HIST4H4
Genetics Home Reference (NIH)HIST4H4
Genomic and cartography
GoldenPath hg38 (UCSC)HIST4H4  -     chr12:14770720-14771131 -  12p12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HIST4H4  -     12p12.3   [Description]    (hg19-Feb_2009)
EnsemblHIST4H4 - 12p12.3 [CytoView hg19]  HIST4H4 - 12p12.3 [CytoView hg38]
Mapping of homologs : NCBIHIST4H4 [Mapview hg19]  HIST4H4 [Mapview hg38]
OMIM615069   
Gene and transcription
Genbank (Entrez)AK311916 BC020884
RefSeq transcript (Entrez)NM_175054
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HIST4H4
Cluster EST : UnigeneHs.745457 [ NCBI ]
CGAP (NCI)Hs.745457
Alternative Splicing GalleryENSG00000197837
Gene ExpressionHIST4H4 [ NCBI-GEO ]   HIST4H4 [ EBI - ARRAY_EXPRESS ]   HIST4H4 [ SEEK ]   HIST4H4 [ MEM ]
Gene Expression Viewer (FireBrowse)HIST4H4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)121504
GTEX Portal (Tissue expression)HIST4H4
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62805   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62805  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62805
Splice isoforms : SwissVarP62805
PhosPhoSitePlusP62805
Domaine pattern : Prosite (Expaxy)HISTONE_H4 (PS00047)   
Domains : Interpro (EBI)Histone-fold    Histone_H4    Histone_H4_CS    TAF_TATA-bd   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)H4 (SM00417)  TAF (SM00803)  
Conserved Domain (NCBI)HIST4H4
DMDM Disease mutations121504
Blocks (Seattle)HIST4H4
PDB (SRS)###############################################################################################################################################################################################################################################################   
PDB (PDBSum)###############################################################################################################################################################################################################################################################   
PDB (IMB)###############################################################################################################################################################################################################################################################   
PDB (RSDB)###############################################################################################################################################################################################################################################################   
Structural Biology KnowledgeBase###############################################################################################################################################################################################################################################################   
SCOP (Structural Classification of Proteins)###############################################################################################################################################################################################################################################################   
CATH (Classification of proteins structures)###############################################################################################################################################################################################################################################################   
SuperfamilyP62805
Human Protein AtlasENSG00000197837
Peptide AtlasP62805
HPRD13662
Protein Interaction databases
DIP (DOE-UCLA)P62805
IntAct (EBI)P62805
FunCoupENSG00000197837
BioGRIDHIST4H4
STRING (EMBL)HIST4H4
ZODIACHIST4H4
Ontologies - Pathways
QuickGOP62805
Ontology : AmiGOchromatin silencing at rDNA  nuclear chromosome  nuclear chromosome, telomeric region  nucleosome  nucleosome  nuclear nucleosome  DNA binding  DNA binding  RNA binding  protein binding  extracellular region  nucleus  nucleoplasm  double-strand break repair via nonhomologous end joining  nucleosome assembly  nucleosome assembly  DNA replication-dependent nucleosome assembly  DNA replication-independent nucleosome assembly  DNA-templated transcription, initiation  membrane  telomere capping  protein domain specific binding  extracellular matrix  gene silencing by RNA  telomere organization  CENP-A containing nucleosome assembly  histone binding  histone binding  protein complex  cellular protein metabolic process  negative regulation of megakaryocyte differentiation  negative regulation of gene expression, epigenetic  positive regulation of gene expression, epigenetic  protein heterodimerization activity  protein heterotetramerization  extracellular exosome  beta-catenin-TCF complex assembly  
Ontology : EGO-EBIchromatin silencing at rDNA  nuclear chromosome  nuclear chromosome, telomeric region  nucleosome  nucleosome  nuclear nucleosome  DNA binding  DNA binding  RNA binding  protein binding  extracellular region  nucleus  nucleoplasm  double-strand break repair via nonhomologous end joining  nucleosome assembly  nucleosome assembly  DNA replication-dependent nucleosome assembly  DNA replication-independent nucleosome assembly  DNA-templated transcription, initiation  membrane  telomere capping  protein domain specific binding  extracellular matrix  gene silencing by RNA  telomere organization  CENP-A containing nucleosome assembly  histone binding  histone binding  protein complex  cellular protein metabolic process  negative regulation of megakaryocyte differentiation  negative regulation of gene expression, epigenetic  positive regulation of gene expression, epigenetic  protein heterodimerization activity  protein heterotetramerization  extracellular exosome  beta-catenin-TCF complex assembly  
Pathways : KEGGAlcoholism    Viral carcinogenesis    Systemic lupus erythematosus   
NDEx NetworkHIST4H4
Atlas of Cancer Signalling NetworkHIST4H4
Wikipedia pathwaysHIST4H4
Orthology - Evolution
OrthoDB121504
GeneTree (enSembl)ENSG00000197837
Phylogenetic Trees/Animal Genes : TreeFamHIST4H4
HOVERGENP62805
HOGENOMP62805
Homologs : HomoloGeneHIST4H4
Homology/Alignments : Family Browser (UCSC)HIST4H4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIST4H4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIST4H4
dbVarHIST4H4
ClinVarHIST4H4
1000_GenomesHIST4H4 
Exome Variant ServerHIST4H4
ExAC (Exome Aggregation Consortium)HIST4H4 (select the gene name)
Genetic variants : HAPMAP121504
Genomic Variants (DGV)HIST4H4 [DGVbeta]
DECIPHERHIST4H4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHIST4H4 
Mutations
ICGC Data PortalHIST4H4 
TCGA Data PortalHIST4H4 
Broad Tumor PortalHIST4H4
OASIS PortalHIST4H4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHIST4H4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHIST4H4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIST4H4
DgiDB (Drug Gene Interaction Database)HIST4H4
DoCM (Curated mutations)HIST4H4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIST4H4 (select a term)
intoGenHIST4H4
Cancer3DHIST4H4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615069   
Orphanet
MedgenHIST4H4
Genetic Testing Registry HIST4H4
NextProtP62805 [Medical]
TSGene121504
GENETestsHIST4H4
Huge Navigator HIST4H4 [HugePedia]
snp3D : Map Gene to Disease121504
BioCentury BCIQHIST4H4
ClinGenHIST4H4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD121504
Chemical/Pharm GKB GenePA134931035
Clinical trialHIST4H4
Miscellaneous
canSAR (ICR)HIST4H4 (select the gene name)
Probes
Litterature
PubMed187 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIST4H4
EVEXHIST4H4
GoPubMedHIST4H4
iHOPHIST4H4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:18:56 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.