Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

HIVEP1 (human immunodeficiency virus type I enhancer binding protein 1)

Identity

Alias_namesZNF40
human immunodeficiency virus type I enhancer-binding protein 1
zinc finger protein 40
Alias_symbol (synonym)CIRIP
MBP-1
CRYBP1
PRDII-BF1
ZAS1
Schnurri-1
ZNF40A
Other aliasGAAP
HGNC (Hugo) HIVEP1
LocusID (NCBI) 3096
Atlas_Id 53863
Location 6p24.1  [Link to chromosome band 6p24]
Location_base_pair Starts at 12012491 and ends at 12164999 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DDX39B (6p21.33) / HIVEP1 (6p24.1)HIVEP1 (6p24.1) / DST (6p12.1)HIVEP1 (6p24.1) / HIVEP1 (6p24.1)
HIVEP1 (6p24.1) / MAPK1 (22q11.21)HIVEP1 (6p24.1) / OFCC1 (6p24.3)MTCH1 (6p21.2) / HIVEP1 (6p24.1)
HIVEP1 6p24.1 / DST 6p12.1HIVEP1 6p24.1 / MAPK1 22q11.21HIVEP1 6p24.1 / OFCC1 6p24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  t(6;6)(p12;p24) HIVEP1/DST
HIVEP1/OFCC1 (6p24)
t(6;22)(p24;q11) HIVEP1/MAPK1

External links

Nomenclature
HGNC (Hugo)HIVEP1   4920
Cards
Entrez_Gene (NCBI)HIVEP1  3096  human immunodeficiency virus type I enhancer binding protein 1
AliasesCIRIP; CRYBP1; GAAP; MBP-1; 
PRDII-BF1; Schnurri-1; ZAS1; ZNF40; ZNF40A
GeneCards (Weizmann)HIVEP1
Ensembl hg19 (Hinxton)ENSG00000095951 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000095951 [Gene_View]  ENSG00000095951 [Sequence]  chr6:12012491-12164999 [Contig_View]  HIVEP1 [Vega]
ICGC DataPortalENSG00000095951
TCGA cBioPortalHIVEP1
AceView (NCBI)HIVEP1
Genatlas (Paris)HIVEP1
WikiGenes3096
SOURCE (Princeton)HIVEP1
Genetics Home Reference (NIH)HIVEP1
Genomic and cartography
GoldenPath hg38 (UCSC)HIVEP1  -     chr6:12012491-12164999 +  6p24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HIVEP1  -     6p24.1   [Description]    (hg19-Feb_2009)
EnsemblHIVEP1 - 6p24.1 [CytoView hg19]  HIVEP1 - 6p24.1 [CytoView hg38]
Mapping of homologs : NCBIHIVEP1 [Mapview hg19]  HIVEP1 [Mapview hg38]
OMIM194540   
Gene and transcription
Genbank (Entrez)AA563642 AI033710 AK294338 AY673640 BC028111
RefSeq transcript (Entrez)NM_002114
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HIVEP1
Cluster EST : UnigeneHs.567284 [ NCBI ]
CGAP (NCI)Hs.567284
Alternative Splicing GalleryENSG00000095951
Gene ExpressionHIVEP1 [ NCBI-GEO ]   HIVEP1 [ EBI - ARRAY_EXPRESS ]   HIVEP1 [ SEEK ]   HIVEP1 [ MEM ]
Gene Expression Viewer (FireBrowse)HIVEP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3096
GTEX Portal (Tissue expression)HIVEP1
Human Protein AtlasENSG00000095951-HIVEP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP15822   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP15822  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP15822
Splice isoforms : SwissVarP15822
PhosPhoSitePlusP15822
Domaine pattern : Prosite (Expaxy)ZF_CCHC_HIVEP (PS51811)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)ZF_CCHC_HIVEP    Znf_C2H2_sf    Znf_C2H2_type   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)HIVEP1
DMDM Disease mutations3096
Blocks (Seattle)HIVEP1
PDB (SRS)1BBO    3ZNF    4ZNF   
PDB (PDBSum)1BBO    3ZNF    4ZNF   
PDB (IMB)1BBO    3ZNF    4ZNF   
PDB (RSDB)1BBO    3ZNF    4ZNF   
Structural Biology KnowledgeBase1BBO    3ZNF    4ZNF   
SCOP (Structural Classification of Proteins)1BBO    3ZNF    4ZNF   
CATH (Classification of proteins structures)1BBO    3ZNF    4ZNF   
SuperfamilyP15822
Human Protein Atlas [tissue]ENSG00000095951-HIVEP1 [tissue]
Peptide AtlasP15822
HPRD01925
IPIIPI00783879   IPI00942123   IPI00941780   IPI01011995   IPI01011712   IPI00479492   IPI00946247   IPI00947467   IPI00946595   IPI00947121   IPI00946977   
Protein Interaction databases
DIP (DOE-UCLA)P15822
IntAct (EBI)P15822
FunCoupENSG00000095951
BioGRIDHIVEP1
STRING (EMBL)HIVEP1
ZODIACHIVEP1
Ontologies - Pathways
QuickGOP15822
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  negative regulation of transcription by RNA polymerase II  RNA polymerase II distal enhancer sequence-specific DNA binding  RNA polymerase II transcription factor activity, sequence-specific DNA binding  RNA polymerase II transcription factor activity, sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding  DNA binding  protein binding  nucleus  nucleoplasm  mitochondrion  nuclear body  metal ion binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  negative regulation of transcription by RNA polymerase II  RNA polymerase II distal enhancer sequence-specific DNA binding  RNA polymerase II transcription factor activity, sequence-specific DNA binding  RNA polymerase II transcription factor activity, sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding  DNA binding  protein binding  nucleus  nucleoplasm  mitochondrion  nuclear body  metal ion binding  
NDEx NetworkHIVEP1
Atlas of Cancer Signalling NetworkHIVEP1
Wikipedia pathwaysHIVEP1
Orthology - Evolution
OrthoDB3096
GeneTree (enSembl)ENSG00000095951
Phylogenetic Trees/Animal Genes : TreeFamHIVEP1
HOVERGENP15822
HOGENOMP15822
Homologs : HomoloGeneHIVEP1
Homology/Alignments : Family Browser (UCSC)HIVEP1
Gene fusions - Rearrangements
Fusion : MitelmanHIVEP1/DST [6p24.1/6p12.1]  
Fusion : MitelmanHIVEP1/MAPK1 [6p24.1/22q11.21]  [t(6;22)(p24;q11)]  
Fusion : MitelmanHIVEP1/OFCC1 [6p24.1/6p24.3]  [t(6;6)(p24;p24)]  
Fusion PortalHIVEP1 6p24.1 DST 6p12.1 BRCA
Fusion PortalHIVEP1 6p24.1 MAPK1 22q11.21 LUAD
Fusion PortalHIVEP1 6p24.1 OFCC1 6p24.3 BRCA
Fusion : QuiverHIVEP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHIVEP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HIVEP1
dbVarHIVEP1
ClinVarHIVEP1
1000_GenomesHIVEP1 
Exome Variant ServerHIVEP1
ExAC (Exome Aggregation Consortium)ENSG00000095951
GNOMAD BrowserENSG00000095951
Varsome BrowserHIVEP1
Genetic variants : HAPMAP3096
Genomic Variants (DGV)HIVEP1 [DGVbeta]
DECIPHERHIVEP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHIVEP1 
Mutations
ICGC Data PortalHIVEP1 
TCGA Data PortalHIVEP1 
Broad Tumor PortalHIVEP1
OASIS PortalHIVEP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHIVEP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHIVEP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HIVEP1
DgiDB (Drug Gene Interaction Database)HIVEP1
DoCM (Curated mutations)HIVEP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HIVEP1 (select a term)
intoGenHIVEP1
Cancer3DHIVEP1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM194540   
Orphanet
DisGeNETHIVEP1
MedgenHIVEP1
Genetic Testing Registry HIVEP1
NextProtP15822 [Medical]
TSGene3096
GENETestsHIVEP1
Target ValidationHIVEP1
Huge Navigator HIVEP1 [HugePedia]
snp3D : Map Gene to Disease3096
BioCentury BCIQHIVEP1
ClinGenHIVEP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3096
Chemical/Pharm GKB GenePA29297
Clinical trialHIVEP1
Miscellaneous
canSAR (ICR)HIVEP1 (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHIVEP1
EVEXHIVEP1
GoPubMedHIVEP1
iHOPHIVEP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Aug 27 11:27:06 CEST 2018
Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.