Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HKDC1 (hexokinase domain containing 1)

Identity

Alias_symbol (synonym)FLJ37767
FLJ22761
Other alias-
HGNC (Hugo) HKDC1
LocusID (NCBI) 80201
Atlas_Id 64328
Location 10q22.1  [Link to chromosome band 10q22]
Location_base_pair Starts at 69220303 and ends at 69267559 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HKDC1   23302
Cards
Entrez_Gene (NCBI)HKDC1  80201  hexokinase domain containing 1
Aliases
GeneCards (Weizmann)HKDC1
Ensembl hg19 (Hinxton)ENSG00000156510 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000156510 [Gene_View]  chr10:69220303-69267559 [Contig_View]  HKDC1 [Vega]
ICGC DataPortalENSG00000156510
TCGA cBioPortalHKDC1
AceView (NCBI)HKDC1
Genatlas (Paris)HKDC1
WikiGenes80201
SOURCE (Princeton)HKDC1
Genetics Home Reference (NIH)HKDC1
Genomic and cartography
GoldenPath hg38 (UCSC)HKDC1  -     chr10:69220303-69267559 +  10q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HKDC1  -     10q22.1   [Description]    (hg19-Feb_2009)
EnsemblHKDC1 - 10q22.1 [CytoView hg19]  HKDC1 - 10q22.1 [CytoView hg38]
Mapping of homologs : NCBIHKDC1 [Mapview hg19]  HKDC1 [Mapview hg38]
OMIM617221   
Gene and transcription
Genbank (Entrez)AK026414 AK095086 AK291024 AK303408 BC012337
RefSeq transcript (Entrez)NM_025130
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HKDC1
Cluster EST : UnigeneHs.522988 [ NCBI ]
CGAP (NCI)Hs.522988
Alternative Splicing GalleryENSG00000156510
Gene ExpressionHKDC1 [ NCBI-GEO ]   HKDC1 [ EBI - ARRAY_EXPRESS ]   HKDC1 [ SEEK ]   HKDC1 [ MEM ]
Gene Expression Viewer (FireBrowse)HKDC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80201
GTEX Portal (Tissue expression)HKDC1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ2TB90   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ2TB90  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ2TB90
Splice isoforms : SwissVarQ2TB90
Catalytic activity : Enzyme2.7.1.1 [ Enzyme-Expasy ]   2.7.1.12.7.1.1 [ IntEnz-EBI ]   2.7.1.1 [ BRENDA ]   2.7.1.1 [ KEGG ]   
PhosPhoSitePlusQ2TB90
Domaine pattern : Prosite (Expaxy)HEXOKINASE_1 (PS00378)    HEXOKINASE_2 (PS51748)   
Domains : Interpro (EBI)Hexokinase    Hexokinase_BS    Hexokinase_C    Hexokinase_N   
Domain families : Pfam (Sanger)Hexokinase_1 (PF00349)    Hexokinase_2 (PF03727)   
Domain families : Pfam (NCBI)pfam00349    pfam03727   
Conserved Domain (NCBI)HKDC1
DMDM Disease mutations80201
Blocks (Seattle)HKDC1
SuperfamilyQ2TB90
Human Protein AtlasENSG00000156510
Peptide AtlasQ2TB90
HPRD08006
IPIIPI00414612   IPI00855827   IPI00856069   
Protein Interaction databases
DIP (DOE-UCLA)Q2TB90
IntAct (EBI)Q2TB90
FunCoupENSG00000156510
BioGRIDHKDC1
STRING (EMBL)HKDC1
ZODIACHKDC1
Ontologies - Pathways
QuickGOQ2TB90
Ontology : AmiGOcellular glucose homeostasis  glucokinase activity  ATP binding  glucose binding  mitochondrion  cytosol  glycolytic process  fructokinase activity  mannokinase activity  hexose metabolic process  carbohydrate phosphorylation  glucose 6-phosphate metabolic process  
Ontology : EGO-EBIcellular glucose homeostasis  glucokinase activity  ATP binding  glucose binding  mitochondrion  cytosol  glycolytic process  fructokinase activity  mannokinase activity  hexose metabolic process  carbohydrate phosphorylation  glucose 6-phosphate metabolic process  
Pathways : KEGGGlycolysis / Gluconeogenesis    Fructose and mannose metabolism    Galactose metabolism    Starch and sucrose metabolism    Amino sugar and nucleotide sugar metabolism    Butirosin and neomycin biosynthesis    HIF-1 signaling pathway    Insulin signaling pathway    Type II diabetes mellitus    Carbohydrate digestion and absorption   
NDEx NetworkHKDC1
Atlas of Cancer Signalling NetworkHKDC1
Wikipedia pathwaysHKDC1
Orthology - Evolution
OrthoDB80201
GeneTree (enSembl)ENSG00000156510
Phylogenetic Trees/Animal Genes : TreeFamHKDC1
HOVERGENQ2TB90
HOGENOMQ2TB90
Homologs : HomoloGeneHKDC1
Homology/Alignments : Family Browser (UCSC)HKDC1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHKDC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HKDC1
dbVarHKDC1
ClinVarHKDC1
1000_GenomesHKDC1 
Exome Variant ServerHKDC1
ExAC (Exome Aggregation Consortium)HKDC1 (select the gene name)
Genetic variants : HAPMAP80201
Genomic Variants (DGV)HKDC1 [DGVbeta]
DECIPHERHKDC1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHKDC1 
Mutations
ICGC Data PortalHKDC1 
TCGA Data PortalHKDC1 
Broad Tumor PortalHKDC1
OASIS PortalHKDC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHKDC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHKDC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HKDC1
DgiDB (Drug Gene Interaction Database)HKDC1
DoCM (Curated mutations)HKDC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HKDC1 (select a term)
intoGenHKDC1
Cancer3DHKDC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617221   
Orphanet
MedgenHKDC1
Genetic Testing Registry HKDC1
NextProtQ2TB90 [Medical]
TSGene80201
GENETestsHKDC1
Target ValidationHKDC1
Huge Navigator HKDC1 [HugePedia]
snp3D : Map Gene to Disease80201
BioCentury BCIQHKDC1
ClinGenHKDC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80201
Chemical/Pharm GKB GenePA134866195
Clinical trialHKDC1
Miscellaneous
canSAR (ICR)HKDC1 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHKDC1
EVEXHKDC1
GoPubMedHKDC1
iHOPHKDC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:10:34 CEST 2017

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