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HKR1 (HKR1, GLI-Kruppel zinc finger family member)

Identity

Alias_namesGLI-Kruppel family member HKR1
Alias_symbol (synonym)ZNF875
Other alias
HGNC (Hugo) HKR1
LocusID (NCBI) 284459
Atlas_Id 40828
Location 19q13.12  [Link to chromosome band 19q13]
Location_base_pair Starts at 37825580 and ends at 37855357 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
EVL (14q32.2) / HKR1 (19q13.12)HKR1 (19q13.12) / ATP1A3 (19q13.2)HKR1 (19q13.12) / HKR1 (19q13.12)
HKR1 (19q13.12) / PPP2R3A (3q22.2)NUMB (14q24.2) / HKR1 (19q13.12)PTGDS (9q34.3) / HKR1 (19q13.12)
HKR1 19q13.12 / ATP1A3 19q13.2HKR1 19q13.12 / PPP2R3A 3q22.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HKR1   4928
Cards
Entrez_Gene (NCBI)HKR1  284459  HKR1, GLI-Kruppel zinc finger family member
AliasesZNF875
GeneCards (Weizmann)HKR1
Ensembl hg19 (Hinxton)ENSG00000181666 [Gene_View]  chr19:37825580-37855357 [Contig_View]  HKR1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000181666 [Gene_View]  chr19:37825580-37855357 [Contig_View]  HKR1 [Vega]
ICGC DataPortalENSG00000181666
TCGA cBioPortalHKR1
AceView (NCBI)HKR1
Genatlas (Paris)HKR1
WikiGenes284459
SOURCE (Princeton)HKR1
Genetics Home Reference (NIH)HKR1
Genomic and cartography
GoldenPath hg19 (UCSC)HKR1  -     chr19:37825580-37855357 +  19q13.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)HKR1  -     19q13.12   [Description]    (hg38-Dec_2013)
EnsemblHKR1 - 19q13.12 [CytoView hg19]  HKR1 - 19q13.12 [CytoView hg38]
Mapping of homologs : NCBIHKR1 [Mapview hg19]  HKR1 [Mapview hg38]
OMIM165250   
Gene and transcription
Genbank (Entrez)AB013897 AK056243 AK128116 AK223616 AK299969
RefSeq transcript (Entrez)NM_181786
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011109 NW_004929415
Consensus coding sequences : CCDS (NCBI)HKR1
Cluster EST : UnigeneHs.729090 [ NCBI ]
CGAP (NCI)Hs.729090
Alternative Splicing GalleryENSG00000181666
Gene ExpressionHKR1 [ NCBI-GEO ]   HKR1 [ EBI - ARRAY_EXPRESS ]   HKR1 [ SEEK ]   HKR1 [ MEM ]
Gene Expression Viewer (FireBrowse)HKR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)284459
GTEX Portal (Tissue expression)HKR1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP10072   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP10072  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP10072
Splice isoforms : SwissVarP10072
PhosPhoSitePlusP10072
Domaine pattern : Prosite (Expaxy)KRAB (PS50805)    ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)KRAB    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)KRAB (PF01352)    zf-C2H2 (PF00096)   
Domain families : Pfam (NCBI)pfam01352    pfam00096   
Domain families : Smart (EMBL)KRAB (SM00349)  ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)HKR1
DMDM Disease mutations284459
Blocks (Seattle)HKR1
SuperfamilyP10072
Human Protein AtlasENSG00000181666
Peptide AtlasP10072
HPRD01314
IPIIPI00018891   IPI00477097   IPI00909574   IPI00645231   IPI00604493   IPI01010988   
Protein Interaction databases
DIP (DOE-UCLA)P10072
IntAct (EBI)P10072
FunCoupENSG00000181666
BioGRIDHKR1
STRING (EMBL)HKR1
ZODIACHKR1
Ontologies - Pathways
QuickGOP10072
Ontology : AmiGODNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  multicellular organism development  metal ion binding  
Ontology : EGO-EBIDNA binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  multicellular organism development  metal ion binding  
NDEx NetworkHKR1
Atlas of Cancer Signalling NetworkHKR1
Wikipedia pathwaysHKR1
Orthology - Evolution
OrthoDB284459
GeneTree (enSembl)ENSG00000181666
Phylogenetic Trees/Animal Genes : TreeFamHKR1
HOVERGENP10072
HOGENOMP10072
Homologs : HomoloGeneHKR1
Homology/Alignments : Family Browser (UCSC)HKR1
Gene fusions - Rearrangements
Fusion : MitelmanHKR1/ATP1A3 [19q13.12/19q13.2]  
Fusion : MitelmanHKR1/PPP2R3A [19q13.12/3q22.2]  [t(3;19)(q22;q13)]  
Fusion: TCGAHKR1 19q13.12 ATP1A3 19q13.2 OV
Fusion: TCGAHKR1 19q13.12 PPP2R3A 3q22.2 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHKR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HKR1
dbVarHKR1
ClinVarHKR1
1000_GenomesHKR1 
Exome Variant ServerHKR1
ExAC (Exome Aggregation Consortium)HKR1 (select the gene name)
Genetic variants : HAPMAP284459
Genomic Variants (DGV)HKR1 [DGVbeta]
DECIPHER (Syndromes)19:37825580-37855357  ENSG00000181666
CONAN: Copy Number AnalysisHKR1 
Mutations
ICGC Data PortalHKR1 
TCGA Data PortalHKR1 
Broad Tumor PortalHKR1
OASIS PortalHKR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHKR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHKR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HKR1
DgiDB (Drug Gene Interaction Database)HKR1
DoCM (Curated mutations)HKR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HKR1 (select a term)
intoGenHKR1
Cancer3DHKR1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM165250   
Orphanet
MedgenHKR1
Genetic Testing Registry HKR1
NextProtP10072 [Medical]
TSGene284459
GENETestsHKR1
Huge Navigator HKR1 [HugePedia]
snp3D : Map Gene to Disease284459
BioCentury BCIQHKR1
ClinGenHKR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD284459
Chemical/Pharm GKB GenePA29306
Clinical trialHKR1
Miscellaneous
canSAR (ICR)HKR1 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHKR1
EVEXHKR1
GoPubMedHKR1
iHOPHKR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:09:12 CET 2017

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