Identity
HGNC
LOCATION
6p21.32
LOCUSID
ALIAS
D6S221E,RING7
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3109
MIM: 142856
HGNC: 4935
Ensembl: ENSG00000242574
Variants:
dbSNP: 3109
ClinVar: 3109
TCGA: ENSG00000242574
COSMIC: HLA-DMB
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000242574 | ENST00000414017 | H0Y7A2 |
| ENSG00000242574 | ENST00000418107 | P28068 |
| ENSG00000242574 | ENST00000418107 | A0A1V0E3P2 |
| ENSG00000242574 | ENST00000438510 | H0Y4B8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36870854 | 2023 | HLA-DMB alleles and haplotypes in Ecuador (Cuenca) Amerindians: Importance for HLA and disease studies. | 0 |
| 36870854 | 2023 | HLA-DMB alleles and haplotypes in Ecuador (Cuenca) Amerindians: Importance for HLA and disease studies. | 0 |
| 26062997 | 2015 | Evaluating the Role of HLA-DM in MHC Class II-Peptide Association Reactions. | 14 |
| 26062997 | 2015 | Evaluating the Role of HLA-DM in MHC Class II-Peptide Association Reactions. | 14 |
| 25008864 | 2014 | SNP screening of central MHC-identified HLA-DMB as a candidate susceptibility gene for HIV-related Kaposi's sarcoma. | 12 |
| 25008864 | 2014 | SNP screening of central MHC-identified HLA-DMB as a candidate susceptibility gene for HIV-related Kaposi's sarcoma. | 12 |
| 22309257 | 2012 | Analysis of HLA-DM polymorphisms in the Chinese Han population. | 2 |
| 23260142 | 2012 | Crystal structure of the HLA-DM-HLA-DR1 complex defines mechanisms for rapid peptide selection. | 102 |
| 22309257 | 2012 | Analysis of HLA-DM polymorphisms in the Chinese Han population. | 2 |
| 23260142 | 2012 | Crystal structure of the HLA-DM-HLA-DR1 complex defines mechanisms for rapid peptide selection. | 102 |
| 21622867 | 2011 | Forced expression of HLA-DM at the surface of dendritic cells increases loading of synthetic peptides on MHC class II molecules and modulates T cell responses. | 5 |
| 21622867 | 2011 | Forced expression of HLA-DM at the surface of dendritic cells increases loading of synthetic peptides on MHC class II molecules and modulates T cell responses. | 5 |
| 20038641 | 2010 | Cutting edge: HLA-DM-mediated peptide exchange functions normally on MHC class II-peptide complexes that have been weakened by elimination of a conserved hydrogen bond. | 26 |
| 20237496 | 2010 | New genetic associations detected in a host response study to hepatitis B vaccine. | 37 |
| 20408893 | 2010 | DM influences the abundance of major histocompatibility complex class II alleles with low affinity for class II-associated invariant chain peptides via multiple mechanisms. | 15 |
Citation
Dessen P
HLA-DMB (major histocompatibility complex, class II, DM beta)
Atlas Genet Cytogenet Oncol Haematol. 2009-03-01
Online version: http://atlasgeneticsoncology.org/gene/50693/hla-dmb
