Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

HLA-DPB1 (major histocompatibility complex, class II, DP beta 1)

Identity

Other namesDPB1
HLA-DP
HLA-DP1B
HLA-DPB
HGNC (Hugo) HLA-DPB1
LocusID (NCBI) 3115
Location 6p21.32
Location_base_pair Starts at 33043703 and ends at 33057473 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)HLA-DPB1   4940
Cards
Entrez_Gene (NCBI)HLA-DPB1  3115  major histocompatibility complex, class II, DP beta 1
GeneCards (Weizmann)HLA-DPB1
Ensembl (Hinxton) [Gene_View]  chr6:33043703-33057473 [Contig_View]  HLA-DPB1 [Vega]
cBioPortalHLA-DPB1
AceView (NCBI)HLA-DPB1
Genatlas (Paris)HLA-DPB1
WikiGenes3115
SOURCE (Princeton)NM_002121
Genomic and cartography
GoldenPath (UCSC)HLA-DPB1  -  6p21.32   chr6:33043703-33057473 +  6p21.32   [Description]    (hg19-Feb_2009)
EnsemblHLA-DPB1 - 6p21.32 [CytoView]
Mapping of homologs : NCBIHLA-DPB1 [Mapview]
OMIM142858   
Gene and transcription
Genbank (Entrez)AB208978 AK291986 AK301322 AK303153 AK313305
RefSeq transcript (Entrez)NM_002121
RefSeq genomic (Entrez)AC_000138 NC_000006 NC_018917 NG_033242 NT_007592 NT_113891 NT_167244 NT_167245 NT_167246 NT_167247 NT_167248 NT_167249 NW_001838980 NW_004929326
Consensus coding sequences : CCDS (NCBI)HLA-DPB1
Cluster EST : UnigeneHs.485130 [ NCBI ]
CGAP (NCI)Hs.485130
Alternative Splicing : Fast-db (Paris)GSHG0025642
Gene ExpressionHLA-DPB1 [ NCBI-GEO ]     HLA-DPB1 [ SEEK ]   HLA-DPB1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP04440 (Uniprot)
NextProtP04440  [Medical]
With graphics : InterProP04440
Splice isoforms : SwissVarP04440 (Swissvar)
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    IG_MHC (PS00290)   
Domains : Interpro (EBI)Ig-like_dom [organisation]   Ig-like_fold [organisation]   Ig/MHC_CS [organisation]   Ig_C1-set [organisation]   MHC_I/II-like_Ag-recog [organisation]   MHC_II_a/b_N [organisation]   MHC_II_b_N [organisation]  
Related proteins : CluSTrP04440
Domain families : Pfam (Sanger)C1-set (PF07654)    MHC_II_beta (PF00969)   
Domain families : Pfam (NCBI)pfam07654    pfam00969   
Domain families : Smart (EMBL)IGc1 (SM00407)  MHC_II_beta (SM00921)  
Domain structure : Prodom (Prabi Lyon)MHC_II_b_N (PD000328)   
DMDM Disease mutations3115
Blocks (Seattle)P04440
PDB (SRS)3LQZ   
PDB (PDBSum)3LQZ   
PDB (IMB)3LQZ   
PDB (RSDB)3LQZ   
Peptide AtlasP04440
HPRD00832
IPIIPI00103082   IPI01025515   IPI00941555   IPI00939139   IPI00645451   IPI01022152   IPI01022515   IPI00971059   IPI00977769   IPI01025879   IPI01020862   IPI00944601   IPI00974082   IPI00922386   IPI00643649   IPI00640057   IPI01013018   IPI00893423   IPI00893284   IPI00871639   IPI00894111   IPI00472604   IPI00894198   IPI00894266   IPI00645418   IPI00852890   IPI00853042   IPI00815678   
Protein Interaction databases
DIP (DOE-UCLA)P04440
IntAct (EBI)P04440
BioGRIDHLA-DPB1
InParanoidP04440
Interologous Interaction database P04440
IntegromeDBHLA-DPB1
STRING (EMBL)HLA-DPB1
Ontologies - Pathways
Ontology : AmiGOGolgi membrane  lysosomal membrane  plasma membrane  cell surface  endosome membrane  ER to Golgi transport vesicle membrane  membrane  cytokine-mediated signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class II  antigen processing and presentation of exogenous peptide antigen via MHC class II  transport vesicle membrane  endocytic vesicle membrane  clathrin-coated endocytic vesicle membrane  T cell costimulation  trans-Golgi network membrane  positive regulation of interferon-gamma production  positive regulation of T cell proliferation  peptide antigen binding  MHC class II protein complex  T cell receptor signaling pathway  positive regulation of T cell activation  interferon-gamma-mediated signaling pathway  integral component of lumenal side of endoplasmic reticulum membrane  
Ontology : EGO-EBIGolgi membrane  lysosomal membrane  plasma membrane  cell surface  endosome membrane  ER to Golgi transport vesicle membrane  membrane  cytokine-mediated signaling pathway  antigen processing and presentation of exogenous peptide antigen via MHC class II  antigen processing and presentation of exogenous peptide antigen via MHC class II  transport vesicle membrane  endocytic vesicle membrane  clathrin-coated endocytic vesicle membrane  T cell costimulation  trans-Golgi network membrane  positive regulation of interferon-gamma production  positive regulation of T cell proliferation  peptide antigen binding  MHC class II protein complex  T cell receptor signaling pathway  positive regulation of T cell activation  interferon-gamma-mediated signaling pathway  integral component of lumenal side of endoplasmic reticulum membrane  
Pathways : KEGGPhagosome    Cell adhesion molecules (CAMs)    Antigen processing and presentation    Intestinal immune network for IgA production    Type I diabetes mellitus    Leishmaniasis    Toxoplasmosis    Staphylococcus aureus infection    Tuberculosis    Influenza A    HTLV-I infection    Herpes simplex infection    Epstein-Barr virus infection    Asthma    Autoimmune thyroid disease    Inflammatory bowel disease (IBD)    Systemic lupus erythematosus    Rheumatoid arthritis    Allograft rejection    Graft-versus-host disease    Viral myocarditis   
Protein Interaction DatabaseHLA-DPB1
Wikipedia pathwaysHLA-DPB1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)HLA-DPB1
snp3D : Map Gene to Disease3115
SNP (GeneSNP Utah)HLA-DPB1
SNP : HGBaseHLA-DPB1
Genetic variants : HAPMAPHLA-DPB1
Exome VariantHLA-DPB1
1000_GenomesHLA-DPB1 
Somatic Mutations in Cancer : COSMICHLA-DPB1 
CONAN: Copy Number AnalysisHLA-DPB1 
Mutations and Diseases : HGMDHLA-DPB1
Mutations and Diseases : intOGenHLA-DPB1
Genomic VariantsHLA-DPB1  HLA-DPB1 [DGVbeta]
dbVarHLA-DPB1
ClinVarHLA-DPB1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM142858   
MedgenHLA-DPB1
GENETestsHLA-DPB1
Disease Genetic AssociationHLA-DPB1
Huge Navigator HLA-DPB1 [HugePedia]  HLA-DPB1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneHLA-DPB1
Homology/Alignments : Family Browser (UCSC)HLA-DPB1
Phylogenetic Trees/Animal Genes : TreeFamHLA-DPB1
Chemical/Protein Interactions : CTD3115
Chemical/Pharm GKB GenePA35064
Clinical trialHLA-DPB1
Other databases
Probes
Litterature
PubMed318 Pubmed reference(s) in Entrez
CoreMineHLA-DPB1
iHOPHLA-DPB1
OncoSearchHLA-DPB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 22 18:54:59 CEST 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.