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HLA-DQB2 (major histocompatibility complex, class II, DQ beta 2)

Identity

Alias_namesHLA-DXB
Other aliasHLA-DQB1
HGNC (Hugo) HLA-DQB2
LocusID (NCBI) 3120
Atlas_Id 64332
Location 6p21.32  [Link to chromosome band 6p21]
Location_base_pair Starts at 32756098 and ends at 32763553 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HLA-DQB2 (6p21.32) / NDUFS1 (2q33.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HLA-DQB2   4945
Cards
Entrez_Gene (NCBI)HLA-DQB2  3120  major histocompatibility complex, class II, DQ beta 2
AliasesHLA-DQB1; HLA-DXB
GeneCards (Weizmann)HLA-DQB2
Ensembl hg19 (Hinxton)ENSG00000232629 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000232629 [Gene_View]  ENSG00000232629 [Sequence]  chr6:32756098-32763553 [Contig_View]  HLA-DQB2 [Vega]
ICGC DataPortalENSG00000232629
TCGA cBioPortalHLA-DQB2
AceView (NCBI)HLA-DQB2
Genatlas (Paris)HLA-DQB2
WikiGenes3120
SOURCE (Princeton)HLA-DQB2
Genetics Home Reference (NIH)HLA-DQB2
Genomic and cartography
GoldenPath hg38 (UCSC)HLA-DQB2  -     chr6:32756098-32763553 -  6p21.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HLA-DQB2  -     6p21.32   [Description]    (hg19-Feb_2009)
EnsemblHLA-DQB2 - 6p21.32 [CytoView hg19]  HLA-DQB2 - 6p21.32 [CytoView hg38]
Mapping of homologs : NCBIHLA-DQB2 [Mapview hg19]  HLA-DQB2 [Mapview hg38]
OMIM615161   
Gene and transcription
Genbank (Entrez)AK098007 BC031995 M95729
RefSeq transcript (Entrez)NM_001198858 NM_001300790 NM_182549
RefSeq genomic (Entrez)NC_000006 NC_018917 NT_113891 NT_167244 NT_167245 NT_167246 NT_167247 NT_167248 NT_167249
Consensus coding sequences : CCDS (NCBI)HLA-DQB2
Cluster EST : UnigeneHs.731563 [ NCBI ]
CGAP (NCI)Hs.731563
Alternative Splicing GalleryENSG00000232629
Gene ExpressionHLA-DQB2 [ NCBI-GEO ]   HLA-DQB2 [ EBI - ARRAY_EXPRESS ]   HLA-DQB2 [ SEEK ]   HLA-DQB2 [ MEM ]
Gene Expression Viewer (FireBrowse)HLA-DQB2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3120
GTEX Portal (Tissue expression)HLA-DQB2
Human Protein AtlasENSG00000232629-HLA-DQB2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP05538   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP05538  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP05538
Splice isoforms : SwissVarP05538
PhosPhoSitePlusP05538
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    IG_MHC (PS00290)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig/MHC_CS    Ig_C1-set    MHC_I/II-like_Ag-recog    MHC_II_a/b_N    MHC_II_b_N   
Domain families : Pfam (Sanger)C1-set (PF07654)    MHC_II_beta (PF00969)   
Domain families : Pfam (NCBI)pfam07654    pfam00969   
Domain families : Smart (EMBL)IGc1 (SM00407)  MHC_II_beta (SM00921)  
Domain structure : Prodom (Prabi Lyon)MHC_II_b_N (PD000328)   
Conserved Domain (NCBI)HLA-DQB2
DMDM Disease mutations3120
Blocks (Seattle)HLA-DQB2
SuperfamilyP05538
Human Protein Atlas [tissue]ENSG00000232629-HLA-DQB2 [tissue]
Peptide AtlasP05538
HPRD09983
IPIIPI00829714   IPI00218637   IPI00641356   IPI00647079   IPI00938268   IPI00914886   IPI00848108   IPI00395557   
Protein Interaction databases
DIP (DOE-UCLA)P05538
IntAct (EBI)P05538
FunCoupENSG00000232629
BioGRIDHLA-DQB2
STRING (EMBL)HLA-DQB2
ZODIACHLA-DQB2
Ontologies - Pathways
QuickGOP05538
Ontology : AmiGO###############################################################################################################################################################################################################################################################                                    
Ontology : EGO-EBI###############################################################################################################################################################################################################################################################                                    
Pathways : KEGGType I diabetes mellitus    Antigen processing and presentation    Cell adhesion molecules (CAMs)   
NDEx NetworkHLA-DQB2
Atlas of Cancer Signalling NetworkHLA-DQB2
Wikipedia pathwaysHLA-DQB2
Orthology - Evolution
OrthoDB3120
GeneTree (enSembl)ENSG00000232629
Phylogenetic Trees/Animal Genes : TreeFamHLA-DQB2
HOVERGENP05538
HOGENOMP05538
Homologs : HomoloGeneHLA-DQB2
Homology/Alignments : Family Browser (UCSC)HLA-DQB2
Gene fusions - Rearrangements
Fusion : QuiverHLA-DQB2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHLA-DQB2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HLA-DQB2
dbVarHLA-DQB2
ClinVarHLA-DQB2
1000_GenomesHLA-DQB2 
Exome Variant ServerHLA-DQB2
ExAC (Exome Aggregation Consortium)ENSG00000232629
GNOMAD BrowserENSG00000232629
Varsome BrowserHLA-DQB2
Genetic variants : HAPMAP3120
Genomic Variants (DGV)HLA-DQB2 [DGVbeta]
DECIPHERHLA-DQB2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHLA-DQB2 
Mutations
ICGC Data PortalHLA-DQB2 
TCGA Data PortalHLA-DQB2 
Broad Tumor PortalHLA-DQB2
OASIS PortalHLA-DQB2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHLA-DQB2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHLA-DQB2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HLA-DQB2
DgiDB (Drug Gene Interaction Database)HLA-DQB2
DoCM (Curated mutations)HLA-DQB2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HLA-DQB2 (select a term)
intoGenHLA-DQB2
Cancer3DHLA-DQB2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615161   
Orphanet
DisGeNETHLA-DQB2
MedgenHLA-DQB2
Genetic Testing Registry HLA-DQB2
NextProtP05538 [Medical]
TSGene3120
GENETestsHLA-DQB2
Target ValidationHLA-DQB2
Huge Navigator HLA-DQB2 [HugePedia]
snp3D : Map Gene to Disease3120
BioCentury BCIQHLA-DQB2
ClinGenHLA-DQB2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3120
Chemical/Pharm GKB GenePA35069
Clinical trialHLA-DQB2
Miscellaneous
canSAR (ICR)HLA-DQB2 (select the gene name)
Probes
Litterature
PubMed1 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHLA-DQB2
EVEXHLA-DQB2
GoPubMedHLA-DQB2
iHOPHLA-DQB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Jul 30 13:49:02 CEST 2018

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