Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HLX (H2.0 like homeobox)

Identity

Alias_namesHLX1
H2.0 (Drosophila)-like homeo box 1
H2.0-like homeobox 1 (Drosophila)
H2.0-like homeobox 1
H2.0-like homeobox
Alias_symbol (synonym)HB24
Other alias
HGNC (Hugo) HLX
LocusID (NCBI) 3142
Atlas_Id 52930
Location 1q41  [Link to chromosome band 1q41]
Location_base_pair Starts at 220879401 and ends at 220885058 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HLX   4978
Cards
Entrez_Gene (NCBI)HLX  3142  H2.0 like homeobox
AliasesHB24; HLX1
GeneCards (Weizmann)HLX
Ensembl hg19 (Hinxton)ENSG00000136630 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000136630 [Gene_View]  chr1:220879401-220885058 [Contig_View]  HLX [Vega]
ICGC DataPortalENSG00000136630
TCGA cBioPortalHLX
AceView (NCBI)HLX
Genatlas (Paris)HLX
WikiGenes3142
SOURCE (Princeton)HLX
Genetics Home Reference (NIH)HLX
Genomic and cartography
GoldenPath hg38 (UCSC)HLX  -     chr1:220879401-220885058 +  1q41   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HLX  -     1q41   [Description]    (hg19-Feb_2009)
EnsemblHLX - 1q41 [CytoView hg19]  HLX - 1q41 [CytoView hg38]
Mapping of homologs : NCBIHLX [Mapview hg19]  HLX [Mapview hg38]
OMIM142995   
Gene and transcription
Genbank (Entrez)AB208812 AK056326 AK127923 AK313298 BC007294
RefSeq transcript (Entrez)NM_021958
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HLX
Cluster EST : UnigeneHs.74870 [ NCBI ]
CGAP (NCI)Hs.74870
Alternative Splicing GalleryENSG00000136630
Gene ExpressionHLX [ NCBI-GEO ]   HLX [ EBI - ARRAY_EXPRESS ]   HLX [ SEEK ]   HLX [ MEM ]
Gene Expression Viewer (FireBrowse)HLX [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3142
GTEX Portal (Tissue expression)HLX
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14774   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14774  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14774
Splice isoforms : SwissVarQ14774
PhosPhoSitePlusQ14774
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_CS    Homeobox_dom    Homeobox_metazoa    HTH_motif   
Domain families : Pfam (Sanger)Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)HLX
DMDM Disease mutations3142
Blocks (Seattle)HLX
SuperfamilyQ14774
Human Protein AtlasENSG00000136630
Peptide AtlasQ14774
HPRD00875
IPIIPI00292164   IPI00643042   
Protein Interaction databases
DIP (DOE-UCLA)Q14774
IntAct (EBI)Q14774
FunCoupENSG00000136630
BioGRIDHLX
STRING (EMBL)HLX
ZODIACHLX
Ontologies - Pathways
QuickGOQ14774
Ontology : AmiGOliver development  protein binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  multicellular organism development  skeletal muscle tissue development  positive regulation of cell proliferation  cell differentiation  sequence-specific DNA binding  positive regulation of T-helper 1 cell differentiation  negative regulation of T-helper 2 cell differentiation  positive regulation of organ growth  enteric nervous system development  embryonic digestive tract morphogenesis  
Ontology : EGO-EBIliver development  protein binding  nucleus  transcription, DNA-templated  regulation of transcription, DNA-templated  multicellular organism development  skeletal muscle tissue development  positive regulation of cell proliferation  cell differentiation  sequence-specific DNA binding  positive regulation of T-helper 1 cell differentiation  negative regulation of T-helper 2 cell differentiation  positive regulation of organ growth  enteric nervous system development  embryonic digestive tract morphogenesis  
NDEx NetworkHLX
Atlas of Cancer Signalling NetworkHLX
Wikipedia pathwaysHLX
Orthology - Evolution
OrthoDB3142
GeneTree (enSembl)ENSG00000136630
Phylogenetic Trees/Animal Genes : TreeFamHLX
HOVERGENQ14774
HOGENOMQ14774
Homologs : HomoloGeneHLX
Homology/Alignments : Family Browser (UCSC)HLX
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHLX [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HLX
dbVarHLX
ClinVarHLX
1000_GenomesHLX 
Exome Variant ServerHLX
ExAC (Exome Aggregation Consortium)HLX (select the gene name)
Genetic variants : HAPMAP3142
Genomic Variants (DGV)HLX [DGVbeta]
DECIPHERHLX [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHLX 
Mutations
ICGC Data PortalHLX 
TCGA Data PortalHLX 
Broad Tumor PortalHLX
OASIS PortalHLX [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHLX  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHLX
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HLX
DgiDB (Drug Gene Interaction Database)HLX
DoCM (Curated mutations)HLX (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HLX (select a term)
intoGenHLX
Cancer3DHLX(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM142995   
Orphanet
MedgenHLX
Genetic Testing Registry HLX
NextProtQ14774 [Medical]
TSGene3142
GENETestsHLX
Target ValidationHLX
Huge Navigator HLX [HugePedia]
snp3D : Map Gene to Disease3142
BioCentury BCIQHLX
ClinGenHLX
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3142
Chemical/Pharm GKB GenePA162391017
Clinical trialHLX
Miscellaneous
canSAR (ICR)HLX (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHLX
EVEXHLX
GoPubMedHLX
iHOPHLX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 25 19:11:47 CEST 2017

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