HMGB1 (high-mobility group box 1)

Identity

Other names	DKFZp686A04236
	HMG1
	HMG3
	SBP-1
HGNC	HMGB1
Location	13q12
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	HMGB1   4983
Entrez_Gene	HMGB1  3146  high-mobility group box 1
	Cards
GeneCards	HMGB1
Ensembl	HMGB1 [Search_View]   ENSG00000189403 [Gene_View]
Genatlas	HMGB1
GeneLynx	HMGB1
eGenome	HMGB1
euGene	3146
	Genomic and cartography
GoldenPath	HMGB1  -  13q12   chr13:29930879-29938081 -  13q12.3   [Description]    (hg18-March_2006)
Ensembl	HMGB1 - 13q12.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	HMGB1
	Gene and transcription
Genbank	AA430980 [ ENTREZ ]
Genbank	AB208998 [ ENTREZ ]
Genbank	AK057120 [ ENTREZ ]
Genbank	AK122825 [ ENTREZ ]
Genbank	AK291494 [ ENTREZ ]
RefSeq	NM_002128 [ SRS ]    NM_002128 [ ENTREZ ]
RefSeq	AC_000056 [ SRS ]    AC_000056 [ ENTREZ ]
RefSeq	AC_000145 [ SRS ]    AC_000145 [ ENTREZ ]
RefSeq	NC_000013 [ SRS ]    NC_000013 [ ENTREZ ]
RefSeq	NT_024524 [ SRS ]    NT_024524 [ ENTREZ ]
RefSeq	NW_001838071 [ SRS ]    NW_001838071 [ ENTREZ ]
RefSeq	NW_925473 [ SRS ]    NW_925473 [ ENTREZ ]
AceView	HMGB1 AceView - NCBI
Unigene	Hs.712556 [ SRS ]    Hs.712556 [ NCBI ]     HS712556 [ spliceNest ]
Fast-db	2251 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P09429 [ SRS]    P09429 [ EXPASY ]     P09429 [ INTERPRO ]     P09429 [ UNIPROT ]
Prosite	PS00353 HMG_BOX_1 [ SRS ]    PS00353 HMG_BOX_1 [ Expasy ]
Prosite	PS50118 HMG_BOX_2 [ SRS ]    PS50118 HMG_BOX_2 [ Expasy ]
Interpro	IPR000910 HMG_1/2_box [ SRS ]    IPR000910 HMG_1/2_box [ EBI ]
Interpro	IPR000135 HMG_1/2_box_subgr [ SRS ]    IPR000135 HMG_1/2_box_subgr [ EBI ]
CluSTr	P09429
Pfam	PF00505 HMG_box [ SRS ]    PF00505 HMG_box [ Sanger ]    pfam00505 [ NCBI-CDD ]
Smart	SM00398 HMG [EMBL]
Blocks	P09429
PDB	2YRQ [ SRS ]    2YRQ [ PdbSum ],   2YRQ [ IMB ]   2YRQ [ RSDB ]
HPRD	01228
	Protein Interaction databases
DIP	P09429
IntAct	P09429
	Polymorphism : SNP, mutations, diseases
OMIM	163905    [ map ]
GENECLINICS	163905
SNP	HMGB1 [dbSNP-NCBI]
SNP	NM_002128 [SNP-NCI]
SNP	HMGB1 [GeneSNPs - Utah]  HMGB1] [HGBASE - SRS]
HAPMAP	HMGB1 [HAPMAP]
COSMIC	HMGB1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	HMGB1
	General knowledge
Family Browser	HMGB1 [UCSC Family Browser]
SOURCE	NM_002128
SMD	Hs.712556
SAGE	Hs.712556
GO	chromatin [Amigo]  chromatin
GO	condensed chromosome [Amigo]  condensed chromosome
GO	DNA binding [Amigo]  DNA binding
GO	nucleus [Amigo]  nucleus
GO	nucleus [Amigo]  nucleus
GO	DNA unwinding during replication [Amigo]  DNA unwinding during replication
GO	DNA repair [Amigo]  DNA repair
GO	base-excision repair, DNA ligation [Amigo]  base-excision repair, DNA ligation
GO	DNA recombination [Amigo]  DNA recombination
GO	establishment and/or maintenance of chromatin architecture [Amigo]  establishment and/or maintenance of chromatin architecture
GO	regulation of transcription, DNA-dependent [Amigo]  regulation of transcription, DNA-dependent
GO	regulation of transcription from RNA polymerase II promoter [Amigo]  regulation of transcription from RNA polymerase II promoter
GO	anti-apoptosis [Amigo]  anti-apoptosis
GO	signal transduction [Amigo]  signal transduction
GO	transcription factor binding [Amigo]  transcription factor binding
GO	DNA bending activity [Amigo]  DNA bending activity
GO	negative regulation of transcriptional preinitiation complex assembly [Amigo]  negative regulation of transcriptional preinitiation complex assembly
BIOCARTA	Apoptotic DNA fragmentation and tissue homeostasis    [Genes]
BIOCARTA	The information-processing pathway at the IFN-beta enhancer    [Genes]
PubGene	HMGB1
TreeFam	HMGB1
CTD	3146 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	HMGB1 Related clones (RZPD - Berlin)
	PubMed
PubMed	118 Pubmed reference(s) in LocusLink

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:14:24 2008