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HMGN3 (high mobility group nucleosomal binding domain 3)

Identity

Alias (NCBI)PNAS-24
PNAS-25
TRIP7
HGNC (Hugo) HMGN3
HGNC Previous nameTRIP7
HGNC Previous namethyroid hormone receptor interactor 7
LocusID (NCBI) 9324
Atlas_Id 46679
Location 6q14.1  [Link to chromosome band 6q14]
Location_base_pair Starts at 79201245 and ends at 79234682 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BC070061 () / HMGN3 (6q14.1)HMGN3 (6q14.1) / HMGN3 (6q14.1)HMGN3 (6q14.1) / NCOA2 (8q13.3)
HMGN3 (6q14.1) / PAQR8 (6p12.2)HMGN3 (6q14.1) / TMEM5 (12q14.2)TNRC18 (7p22.1) / HMGN3 (6q14.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)HMGN3   12312
Cards
Entrez_Gene (NCBI)HMGN3    high mobility group nucleosomal binding domain 3
AliasesPNAS-24; PNAS-25; TRIP7
GeneCards (Weizmann)HMGN3
Ensembl hg19 (Hinxton)ENSG00000118418 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000118418 [Gene_View]  ENSG00000118418 [Sequence]  chr6:79201245-79234682 [Contig_View]  HMGN3 [Vega]
ICGC DataPortalENSG00000118418
TCGA cBioPortalHMGN3
AceView (NCBI)HMGN3
Genatlas (Paris)HMGN3
SOURCE (Princeton)HMGN3
Genetics Home Reference (NIH)HMGN3
Genomic and cartography
GoldenPath hg38 (UCSC)HMGN3  -     chr6:79201245-79234682 -  6q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HMGN3  -     6q14.1   [Description]    (hg19-Feb_2009)
GoldenPathHMGN3 - 6q14.1 [CytoView hg19]  HMGN3 - 6q14.1 [CytoView hg38]
ImmunoBaseENSG00000118418
Genome Data Viewer NCBIHMGN3 [Mapview hg19]  
OMIM604502   
Gene and transcription
Genbank (Entrez)AF274949 AF401520 AI028183 AI672466 AK124181
RefSeq transcript (Entrez)NM_001201362 NM_001201363 NM_001318884 NM_001318885 NM_001318886 NM_001318887 NM_001318888 NM_004242 NM_138730
Consensus coding sequences : CCDS (NCBI)HMGN3
Gene ExpressionHMGN3 [ NCBI-GEO ]   HMGN3 [ EBI - ARRAY_EXPRESS ]   HMGN3 [ SEEK ]   HMGN3 [ MEM ]
Gene Expression Viewer (FireBrowse)HMGN3 [ Firebrowse - Broad ]
GenevisibleExpression of HMGN3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9324
GTEX Portal (Tissue expression)HMGN3
Human Protein AtlasENSG00000118418-HMGN3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15651   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15651  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15651
PhosPhoSitePlusQ15651
Domaine pattern : Prosite (Expaxy)HMG14_17 (PS00355)   
Domains : Interpro (EBI)HMGN3    HMGN_fam   
Domain families : Pfam (Sanger)HMG14_17 (PF01101)   
Domain families : Pfam (NCBI)pfam01101   
Domain families : Smart (EMBL)HMG17 (SM00527)  
Conserved Domain (NCBI)HMGN3
SuperfamilyQ15651
AlphaFold pdb e-kbQ15651   
Human Protein Atlas [tissue]ENSG00000118418-HMGN3 [tissue]
HPRD16062
Protein Interaction databases
DIP (DOE-UCLA)Q15651
IntAct (EBI)Q15651
BioGRIDHMGN3
STRING (EMBL)HMGN3
ZODIACHMGN3
Ontologies - Pathways
QuickGOQ15651
Ontology : AmiGOchromatin  chromatin binding  nucleus  nucleoplasm  cytosol  chromatin organization  biological_process  nucleosomal DNA binding  positive regulation of transcription by RNA polymerase II  thyroid hormone receptor binding  regulation of insulin secretion involved in cellular response to glucose stimulus  
Ontology : EGO-EBIchromatin  chromatin binding  nucleus  nucleoplasm  cytosol  chromatin organization  biological_process  nucleosomal DNA binding  positive regulation of transcription by RNA polymerase II  thyroid hormone receptor binding  regulation of insulin secretion involved in cellular response to glucose stimulus  
NDEx NetworkHMGN3
Atlas of Cancer Signalling NetworkHMGN3
Wikipedia pathwaysHMGN3
Orthology - Evolution
OrthoDB9324
GeneTree (enSembl)ENSG00000118418
Phylogenetic Trees/Animal Genes : TreeFamHMGN3
Homologs : HomoloGeneHMGN3
Homology/Alignments : Family Browser (UCSC)HMGN3
Gene fusions - Rearrangements
Fusion : MitelmanHMGN3/PAQR8 [6q14.1/6p12.2]  
Fusion Cancer (Beijing)BC070061 [HMGN3]  -  6q14.1 [FUSC002615]  [FUSC002615]
Fusion : QuiverHMGN3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHMGN3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HMGN3
dbVarHMGN3
ClinVarHMGN3
MonarchHMGN3
1000_GenomesHMGN3 
Exome Variant ServerHMGN3
GNOMAD BrowserENSG00000118418
Varsome BrowserHMGN3
ACMGHMGN3 variants
VarityQ15651
Genomic Variants (DGV)HMGN3 [DGVbeta]
DECIPHERHMGN3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHMGN3 
Mutations
ICGC Data PortalHMGN3 
TCGA Data PortalHMGN3 
Broad Tumor PortalHMGN3
OASIS PortalHMGN3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHMGN3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DHMGN3
Mutations and Diseases : HGMDHMGN3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaHMGN3
DgiDB (Drug Gene Interaction Database)HMGN3
DoCM (Curated mutations)HMGN3
CIViC (Clinical Interpretations of Variants in Cancer)HMGN3
Cancer3DHMGN3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604502   
Orphanet
DisGeNETHMGN3
MedgenHMGN3
Genetic Testing Registry HMGN3
NextProtQ15651 [Medical]
GENETestsHMGN3
Target ValidationHMGN3
Huge Navigator HMGN3 [HugePedia]
ClinGenHMGN3
Clinical trials, drugs, therapy
MyCancerGenomeHMGN3
Protein Interactions : CTDHMGN3
Pharm GKB GenePA36990
PharosQ15651
Clinical trialHMGN3
Miscellaneous
canSAR (ICR)HMGN3
HarmonizomeHMGN3
DataMed IndexHMGN3
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXHMGN3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:12:36 CEST 2021

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