HMGXB4 (HMG-box containing 4)

2007-04-01  

Identity

HGNC
HMGXB4
LOCATION
22q12.3
LOCUSID
10042
ALIAS
HMG2L1,HMGBCG,P53N,THC211630
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10042
MIM: 604702
HGNC: 5003
Ensembl: ENSG00000100281

Variants:

dbSNP: 10042
ClinVar: 10042
TCGA: ENSG00000100281
COSMIC: HMGXB4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100281ENST00000216106Q9UGU5
ENSG00000100281ENST00000418170F8WDU7
ENSG00000100281ENST00000420166B0QXZ9
ENSG00000100281ENST00000455359B0QXZ8

Expression (GTEx)

0
5
10
15
20
25
30
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
208006032010Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.12
205112322010Repression of smooth muscle differentiation by a novel high mobility group box-containing protein, HMG2L1.7
176719662008Gene-based SNP mapping of a psychotic bipolar affective disorder linkage region on 22q12.3: association with HMG2L1 and TOM1.5
176719662008Gene-based SNP mapping of a psychotic bipolar affective disorder linkage region on 22q12.3: association with HMG2L1 and TOM1.5
265475062016Integrative analysis of copy number and gene expression data suggests novel pathogenetic mechanisms in primary myelofibrosis.2

Citation

Dessen P

HMGXB4 (HMG-box containing 4)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/47370/hmgxb4