| Nomenclature |
|---|
| HGNC (Hugo) | HMX2 5018 |
| Cards |
|---|
| Entrez_Gene (NCBI) | HMX2 3167 H6 family homeobox 2 |
| Aliases | H6L; Nkx5-2 |
| GeneCards (Weizmann) | HMX2 |
| Ensembl hg19 (Hinxton) | ENSG00000188816 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000188816 [Gene_View] ENSG00000188816 [Sequence] chr10:123148122-123150672 [Contig_View] HMX2 [Vega] |
| ICGC DataPortal | ENSG00000188816 |
| TCGA cBioPortal | HMX2 |
| AceView (NCBI) | HMX2 |
| Genatlas (Paris) | HMX2 |
| WikiGenes | 3167 |
| SOURCE (Princeton) | HMX2 |
| Genetics Home Reference (NIH) | HMX2 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | HMX2 - chr10:123148122-123150672 + 10q26.13 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | HMX2 - 10q26.13 [Description] (hg19-Feb_2009) |
| Ensembl | HMX2 - 10q26.13 [CytoView hg19] HMX2 - 10q26.13 [CytoView hg38] |
| Mapping of homologs : NCBI | HMX2 [Mapview hg19] HMX2 [Mapview hg38] |
| OMIM | 600647 |
| Gene and transcription |
|---|
| Genbank (Entrez) | BC132758 BC137139 BQ929484 |
| RefSeq transcript (Entrez) | NM_005519 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | HMX2 |
| Cluster EST : Unigene | Hs.444756 [ NCBI ] |
| CGAP (NCI) | Hs.444756 |
| Alternative Splicing Gallery | ENSG00000188816 |
| Gene Expression | HMX2 [ NCBI-GEO ] HMX2 [ EBI - ARRAY_EXPRESS ]
HMX2 [ SEEK ] HMX2 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | HMX2 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 3167 |
| GTEX Portal (Tissue expression) | HMX2 |
| Human Protein Atlas | ENSG00000188816-HMX2 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | A2RU54 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | A2RU54 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | A2RU54 |
| Splice isoforms : SwissVar | A2RU54 |
| PhosPhoSitePlus | A2RU54 |
| Domaine pattern : Prosite (Expaxy) | HOMEOBOX_1 (PS00027) HOMEOBOX_2 (PS50071) |
| Domains : Interpro (EBI) | Homeobox-like Homeobox_CS Homeobox_dom Homeobox_metazoa |
| Domain families : Pfam (Sanger) | Homeobox (PF00046) |
| Domain families : Pfam (NCBI) | pfam00046 |
| Domain families : Smart (EMBL) | HOX (SM00389) |
| Conserved Domain (NCBI) | HMX2 |
| DMDM Disease mutations | 3167 |
| Blocks (Seattle) | HMX2 |
| Superfamily | A2RU54 |
| Human Protein Atlas [tissue] | ENSG00000188816-HMX2 [tissue] |
| Peptide Atlas | A2RU54 |
| HPRD | 18780 |
| IPI | IPI00398900 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | A2RU54 |
| IntAct (EBI) | A2RU54 |
| FunCoup | ENSG00000188816 |
| BioGRID | HMX2 |
| STRING (EMBL) | HMX2 |
| ZODIAC | HMX2 |
| Ontologies - Pathways |
|---|
| QuickGO | A2RU54 |
| Ontology : AmiGO | nucleus transcription, DNA-templated regulation of transcription, DNA-templated brain development positive regulation of cell proliferation cell differentiation inner ear morphogenesis sequence-specific DNA binding positive regulation of mRNA splicing, via spliceosome |
| Ontology : EGO-EBI | nucleus transcription, DNA-templated regulation of transcription, DNA-templated brain development positive regulation of cell proliferation cell differentiation inner ear morphogenesis sequence-specific DNA binding positive regulation of mRNA splicing, via spliceosome |
| NDEx Network | HMX2 |
| Atlas of Cancer Signalling Network | HMX2 |
| Wikipedia pathways | HMX2 |
| Orthology - Evolution |
|---|
| OrthoDB | 3167 |
| GeneTree (enSembl) | ENSG00000188816 |
| Phylogenetic Trees/Animal Genes : TreeFam | HMX2 |
| HOVERGEN | A2RU54 |
| HOGENOM | A2RU54 |
| Homologs : HomoloGene | HMX2 |
| Homology/Alignments : Family Browser (UCSC) | HMX2 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | HMX2 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | HMX2 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | HMX2 |
| dbVar | HMX2 |
| ClinVar | HMX2 |
| 1000_Genomes | HMX2 |
| Exome Variant Server | HMX2 |
| ExAC (Exome Aggregation Consortium) | ENSG00000188816 |
| GNOMAD Browser | ENSG00000188816 |
| Genetic variants : HAPMAP | 3167 |
| Genomic Variants (DGV) | HMX2 [DGVbeta] |
| DECIPHER | HMX2 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | HMX2 |
| Mutations |
|---|
| ICGC Data Portal | HMX2 |
| TCGA Data Portal | HMX2 |
| Broad Tumor Portal | HMX2 |
| OASIS Portal | HMX2 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | HMX2 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | HMX2 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search HMX2 |
| DgiDB (Drug Gene Interaction Database) | HMX2 |
| DoCM (Curated mutations) | HMX2 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | HMX2 (select a term) |
| intoGen | HMX2 |
| Cancer3D | HMX2(select the gene name) |
| Impact of mutations | [PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 600647 |
| Orphanet | |
| DisGeNET | HMX2 |
| Medgen | HMX2 |
| Genetic Testing Registry | HMX2
|
| NextProt | A2RU54 [Medical] |
| TSGene | 3167 |
| GENETests | HMX2 |
| Target Validation | HMX2 |
| Huge Navigator |
HMX2 [HugePedia] |
| snp3D : Map Gene to Disease | 3167 |
| BioCentury BCIQ | HMX2 |
| ClinGen | HMX2 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 3167 |
| Chemical/Pharm GKB Gene | PA29345 |
| Clinical trial | HMX2 |
| Miscellaneous |
|---|
| canSAR (ICR) | HMX2 (select the gene name) |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 6 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | HMX2 |
| EVEX | HMX2 |
| GoPubMed | HMX2 |
| iHOP | HMX2 |
