Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HNRNPA1 (heterogeneous nuclear ribonucleoprotein A1)

Identity

Alias_namesHNRPA1
Alias_symbol (synonym)hnRNPA1
hnRNP-A1
ALS20
Other aliasALS19
HNRPA1L3
IBMPFD3
UP 1
hnRNP A1
HGNC (Hugo) HNRNPA1
LocusID (NCBI) 3178
Atlas_Id 43803
Location 12q13.13  [Link to chromosome band 12q13]
Location_base_pair Starts at 54280690 and ends at 54285246 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
B4GALT5 (20q13.13) / HNRNPA1 (12q13.13)HNRNPA1 (12q13.13) / BEST3 (12q15)VAT1 (17q21.31) / HNRNPA1 (12q13.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HNRNPA1   5031
Cards
Entrez_Gene (NCBI)HNRNPA1  3178  heterogeneous nuclear ribonucleoprotein A1
AliasesALS19; ALS20; HNRPA1; HNRPA1L3; 
IBMPFD3; UP; hnRNP; hnRNP-A1
GeneCards (Weizmann)HNRNPA1
Ensembl hg19 (Hinxton)ENSG00000135486 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135486 [Gene_View]  chr12:54280690-54285246 [Contig_View]  HNRNPA1 [Vega]
ICGC DataPortalENSG00000135486
TCGA cBioPortalHNRNPA1
AceView (NCBI)HNRNPA1
Genatlas (Paris)HNRNPA1
WikiGenes3178
SOURCE (Princeton)HNRNPA1
Genetics Home Reference (NIH)HNRNPA1
Genomic and cartography
GoldenPath hg38 (UCSC)HNRNPA1  -     chr12:54280690-54285246 +  12q13.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HNRNPA1  -     12q13.13   [Description]    (hg19-Feb_2009)
EnsemblHNRNPA1 - 12q13.13 [CytoView hg19]  HNRNPA1 - 12q13.13 [CytoView hg38]
Mapping of homologs : NCBIHNRNPA1 [Mapview hg19]  HNRNPA1 [Mapview hg38]
OMIM164017   615424   615426   
Gene and transcription
Genbank (Entrez)###############################################################################################################################################################################################################################################################
RefSeq transcript (Entrez)NM_002136 NM_031157
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HNRNPA1
Cluster EST : UnigeneHs.655424 [ NCBI ]
CGAP (NCI)Hs.655424
Alternative Splicing GalleryENSG00000135486
Gene ExpressionHNRNPA1 [ NCBI-GEO ]   HNRNPA1 [ EBI - ARRAY_EXPRESS ]   HNRNPA1 [ SEEK ]   HNRNPA1 [ MEM ]
Gene Expression Viewer (FireBrowse)HNRNPA1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3178
GTEX Portal (Tissue expression)HNRNPA1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09651   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP09651  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP09651
Splice isoforms : SwissVarP09651
PhosPhoSitePlusP09651
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)HnRNPA1    Nucleotide-bd_a/b_plait    RRM_dom   
Domain families : Pfam (Sanger)HnRNPA1 (PF11627)    RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam11627    pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)HNRNPA1
DMDM Disease mutations3178
Blocks (Seattle)HNRNPA1
PDB (SRS)1HA1    1L3K    1PGZ    1PO6    1U1K    1U1L    1U1M    1U1N    1U1O    1U1P    1U1Q    1U1R    1UP1    2H4M    2LYV    2UP1    4YOE   
PDB (PDBSum)1HA1    1L3K    1PGZ    1PO6    1U1K    1U1L    1U1M    1U1N    1U1O    1U1P    1U1Q    1U1R    1UP1    2H4M    2LYV    2UP1    4YOE   
PDB (IMB)1HA1    1L3K    1PGZ    1PO6    1U1K    1U1L    1U1M    1U1N    1U1O    1U1P    1U1Q    1U1R    1UP1    2H4M    2LYV    2UP1    4YOE   
PDB (RSDB)1HA1    1L3K    1PGZ    1PO6    1U1K    1U1L    1U1M    1U1N    1U1O    1U1P    1U1Q    1U1R    1UP1    2H4M    2LYV    2UP1    4YOE   
Structural Biology KnowledgeBase1HA1    1L3K    1PGZ    1PO6    1U1K    1U1L    1U1M    1U1N    1U1O    1U1P    1U1Q    1U1R    1UP1    2H4M    2LYV    2UP1    4YOE   
SCOP (Structural Classification of Proteins)1HA1    1L3K    1PGZ    1PO6    1U1K    1U1L    1U1M    1U1N    1U1O    1U1P    1U1Q    1U1R    1UP1    2H4M    2LYV    2UP1    4YOE   
CATH (Classification of proteins structures)1HA1    1L3K    1PGZ    1PO6    1U1K    1U1L    1U1M    1U1N    1U1O    1U1P    1U1Q    1U1R    1UP1    2H4M    2LYV    2UP1    4YOE   
SuperfamilyP09651
Human Protein AtlasENSG00000135486
Peptide AtlasP09651
HPRD01242
IPIIPI00215965   IPI00465365   IPI00797148   IPI01021324   IPI00908994   IPI01022060   IPI01021812   IPI01022460   IPI01022641   IPI01022218   IPI01022306   IPI01021093   IPI01022801   IPI00644968   
Protein Interaction databases
DIP (DOE-UCLA)P09651
IntAct (EBI)P09651
FunCoupENSG00000135486
BioGRIDHNRNPA1
STRING (EMBL)HNRNPA1
ZODIACHNRNPA1
Ontologies - Pathways
QuickGOP09651
Ontology : AmiGOregulation of alternative mRNA splicing, via spliceosome  mRNA splicing, via spliceosome  mRNA splicing, via spliceosome  single-stranded DNA binding  RNA binding  single-stranded RNA binding  protein binding  nucleus  nucleoplasm  nucleoplasm  spliceosomal complex  cytoplasm  mRNA processing  RNA export from nucleus  fibroblast growth factor receptor signaling pathway  gene expression  membrane  viral process  intracellular ribonucleoprotein complex  negative regulation of telomere maintenance via telomerase  positive regulation of telomere maintenance via telomerase  pre-mRNA binding  cellular response to glucose starvation  mRNA transport  nuclear export  nuclear import  telomeric repeat-containing RNA binding  extracellular exosome  catalytic step 2 spliceosome  G-rich strand telomeric DNA binding  cellular response to sodium arsenite  
Ontology : EGO-EBIregulation of alternative mRNA splicing, via spliceosome  mRNA splicing, via spliceosome  mRNA splicing, via spliceosome  single-stranded DNA binding  RNA binding  single-stranded RNA binding  protein binding  nucleus  nucleoplasm  nucleoplasm  spliceosomal complex  cytoplasm  mRNA processing  RNA export from nucleus  fibroblast growth factor receptor signaling pathway  gene expression  membrane  viral process  intracellular ribonucleoprotein complex  negative regulation of telomere maintenance via telomerase  positive regulation of telomere maintenance via telomerase  pre-mRNA binding  cellular response to glucose starvation  mRNA transport  nuclear export  nuclear import  telomeric repeat-containing RNA binding  extracellular exosome  catalytic step 2 spliceosome  G-rich strand telomeric DNA binding  cellular response to sodium arsenite  
Pathways : KEGGSpliceosome   
NDEx NetworkHNRNPA1
Atlas of Cancer Signalling NetworkHNRNPA1
Wikipedia pathwaysHNRNPA1
Orthology - Evolution
OrthoDB3178
GeneTree (enSembl)ENSG00000135486
Phylogenetic Trees/Animal Genes : TreeFamHNRNPA1
HOVERGENP09651
HOGENOMP09651
Homologs : HomoloGeneHNRNPA1
Homology/Alignments : Family Browser (UCSC)HNRNPA1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHNRNPA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HNRNPA1
dbVarHNRNPA1
ClinVarHNRNPA1
1000_GenomesHNRNPA1 
Exome Variant ServerHNRNPA1
ExAC (Exome Aggregation Consortium)HNRNPA1 (select the gene name)
Genetic variants : HAPMAP3178
Genomic Variants (DGV)HNRNPA1 [DGVbeta]
DECIPHERHNRNPA1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHNRNPA1 
Mutations
ICGC Data PortalHNRNPA1 
TCGA Data PortalHNRNPA1 
Broad Tumor PortalHNRNPA1
OASIS PortalHNRNPA1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHNRNPA1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHNRNPA1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HNRNPA1
DgiDB (Drug Gene Interaction Database)HNRNPA1
DoCM (Curated mutations)HNRNPA1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HNRNPA1 (select a term)
intoGenHNRNPA1
Cancer3DHNRNPA1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM164017    615424    615426   
Orphanet106    10698   
MedgenHNRNPA1
Genetic Testing Registry HNRNPA1
NextProtP09651 [Medical]
TSGene3178
GENETestsHNRNPA1
Target ValidationHNRNPA1
Huge Navigator HNRNPA1 [HugePedia]
snp3D : Map Gene to Disease3178
BioCentury BCIQHNRNPA1
ClinGenHNRNPA1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3178
Chemical/Pharm GKB GenePA162391113
Clinical trialHNRNPA1
Miscellaneous
canSAR (ICR)HNRNPA1 (select the gene name)
Probes
Litterature
PubMed261 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHNRNPA1
EVEXHNRNPA1
GoPubMedHNRNPA1
iHOPHNRNPA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:55:32 CEST 2017

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