Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HNRNPAB (heterogeneous nuclear ribonucleoprotein A/B)

Identity

Alias_namesHNRPAB
Alias_symbol (synonym)ABBP1
FLJ40338
Other alias
HGNC (Hugo) HNRNPAB
LocusID (NCBI) 3182
Atlas_Id 54824
Location 5q35.3  [Link to chromosome band 5q35]
Location_base_pair Starts at 178204507 and ends at 178211183 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CYB561D2 (3p21.31) / HNRNPAB (5q35.3)FAM184A (6q22.31) / HNRNPAB (5q35.3)HNRNPAB (5q35.3) / AGPS (2q31.2)
HNRNPAB (5q35.3) / ATF5 (19q13.33)HNRNPAB (5q35.3) / RAD23A (19p13.2)HNRNPAB (5q35.3) / SAMM50 (22q13.31)
HNRNPAB (5q35.3) / SND1 (7q32.1)LOC100507412 (-) / HNRNPAB (5q35.3)SLC38A6 (14q23.1) / HNRNPAB (5q35.3)
TOB2 (22q13.2) / HNRNPAB (5q35.3)HNRNPAB 5q35.3 / SAMM50 22q13.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HNRNPAB   5034
Cards
Entrez_Gene (NCBI)HNRNPAB  3182  heterogeneous nuclear ribonucleoprotein A/B
AliasesABBP1; HNRPAB
GeneCards (Weizmann)HNRNPAB
Ensembl hg19 (Hinxton)ENSG00000197451 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197451 [Gene_View]  chr5:178204507-178211183 [Contig_View]  HNRNPAB [Vega]
ICGC DataPortalENSG00000197451
TCGA cBioPortalHNRNPAB
AceView (NCBI)HNRNPAB
Genatlas (Paris)HNRNPAB
WikiGenes3182
SOURCE (Princeton)HNRNPAB
Genetics Home Reference (NIH)HNRNPAB
Genomic and cartography
GoldenPath hg38 (UCSC)HNRNPAB  -     chr5:178204507-178211183 +  5q35.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HNRNPAB  -     5q35.3   [Description]    (hg19-Feb_2009)
EnsemblHNRNPAB - 5q35.3 [CytoView hg19]  HNRNPAB - 5q35.3 [CytoView hg38]
Mapping of homologs : NCBIHNRNPAB [Mapview hg19]  HNRNPAB [Mapview hg38]
OMIM602688   
Gene and transcription
Genbank (Entrez)AI199152 AK054600 AK097657 AK223425 BC001616
RefSeq transcript (Entrez)NM_004499 NM_031266
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HNRNPAB
Cluster EST : UnigeneHs.715055 [ NCBI ]
CGAP (NCI)Hs.715055
Alternative Splicing GalleryENSG00000197451
Gene ExpressionHNRNPAB [ NCBI-GEO ]   HNRNPAB [ EBI - ARRAY_EXPRESS ]   HNRNPAB [ SEEK ]   HNRNPAB [ MEM ]
Gene Expression Viewer (FireBrowse)HNRNPAB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3182
GTEX Portal (Tissue expression)HNRNPAB
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99729   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99729  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99729
Splice isoforms : SwissVarQ99729
PhosPhoSitePlusQ99729
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)CARG-binding_factor_N    Nucleotide-bd_a/b_plait    RRM_dom   
Domain families : Pfam (Sanger)CBFNT (PF08143)    RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam08143    pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)HNRNPAB
DMDM Disease mutations3182
Blocks (Seattle)HNRNPAB
PDB (SRS)3S7R   
PDB (PDBSum)3S7R   
PDB (IMB)3S7R   
PDB (RSDB)3S7R   
Structural Biology KnowledgeBase3S7R   
SCOP (Structural Classification of Proteins)3S7R   
CATH (Classification of proteins structures)3S7R   
SuperfamilyQ99729
Human Protein AtlasENSG00000197451
Peptide AtlasQ99729
HPRD04067
IPIIPI00329355   IPI00334587   IPI00334713   IPI00106509   IPI00966854   IPI00964992   IPI00964686   
Protein Interaction databases
DIP (DOE-UCLA)Q99729
IntAct (EBI)Q99729
FunCoupENSG00000197451
BioGRIDHNRNPAB
STRING (EMBL)HNRNPAB
ZODIACHNRNPAB
Ontologies - Pathways
QuickGOQ99729
Ontology : AmiGOepithelial to mesenchymal transition  transcription factor activity, sequence-specific DNA binding  RNA binding  mRNA binding  protein binding  nucleus  nucleoplasm  cytoplasm  intracellular ribonucleoprotein complex  sequence-specific DNA binding  positive regulation of transcription, DNA-templated  RNA polymerase II transcription factor complex  
Ontology : EGO-EBIepithelial to mesenchymal transition  transcription factor activity, sequence-specific DNA binding  RNA binding  mRNA binding  protein binding  nucleus  nucleoplasm  cytoplasm  intracellular ribonucleoprotein complex  sequence-specific DNA binding  positive regulation of transcription, DNA-templated  RNA polymerase II transcription factor complex  
NDEx NetworkHNRNPAB
Atlas of Cancer Signalling NetworkHNRNPAB
Wikipedia pathwaysHNRNPAB
Orthology - Evolution
OrthoDB3182
GeneTree (enSembl)ENSG00000197451
Phylogenetic Trees/Animal Genes : TreeFamHNRNPAB
HOVERGENQ99729
HOGENOMQ99729
Homologs : HomoloGeneHNRNPAB
Homology/Alignments : Family Browser (UCSC)HNRNPAB
Gene fusions - Rearrangements
Fusion : MitelmanHNRNPAB/SAMM50 [5q35.3/22q13.31]  
Fusion: TCGAHNRNPAB 5q35.3 SAMM50 22q13.31 SKCM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHNRNPAB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HNRNPAB
dbVarHNRNPAB
ClinVarHNRNPAB
1000_GenomesHNRNPAB 
Exome Variant ServerHNRNPAB
ExAC (Exome Aggregation Consortium)HNRNPAB (select the gene name)
Genetic variants : HAPMAP3182
Genomic Variants (DGV)HNRNPAB [DGVbeta]
DECIPHERHNRNPAB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHNRNPAB 
Mutations
ICGC Data PortalHNRNPAB 
TCGA Data PortalHNRNPAB 
Broad Tumor PortalHNRNPAB
OASIS PortalHNRNPAB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHNRNPAB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHNRNPAB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HNRNPAB
DgiDB (Drug Gene Interaction Database)HNRNPAB
DoCM (Curated mutations)HNRNPAB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HNRNPAB (select a term)
intoGenHNRNPAB
Cancer3DHNRNPAB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602688   
Orphanet
MedgenHNRNPAB
Genetic Testing Registry HNRNPAB
NextProtQ99729 [Medical]
TSGene3182
GENETestsHNRNPAB
Target ValidationHNRNPAB
Huge Navigator HNRNPAB [HugePedia]
snp3D : Map Gene to Disease3182
BioCentury BCIQHNRNPAB
ClinGenHNRNPAB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3182
Chemical/Pharm GKB GenePA162391196
Clinical trialHNRNPAB
Miscellaneous
canSAR (ICR)HNRNPAB (select the gene name)
Probes
Litterature
PubMed71 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHNRNPAB
EVEXHNRNPAB
GoPubMedHNRNPAB
iHOPHNRNPAB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:03:13 CEST 2017

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