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HNRNPC (heterogeneous nuclear ribonucleoprotein C (C1/C2))

Identity

Alias_namesHNRPC
Alias_symbol (synonym)hnRNPC
Other aliasC1
C2
HNRNP
SNRPC
HGNC (Hugo) HNRNPC
LocusID (NCBI) 3183
Atlas_Id 53547
Location 14q11.2  [Link to chromosome band 14q11]
Location_base_pair Starts at 21209136 and ends at 21269479 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AGBL4 (1p33) / HNRNPC (14q11.2)DIAPH2 (Xq21.33) / HNRNPC (14q11.2)GOLPH3 (5p13.3) / HNRNPC (14q11.2)
HNRNPC (14q11.2) / HNRNPC (14q11.2)HNRNPC (14q11.2) / ZNF219 (14q11.2)RPL31 (2q11.2) / HNRNPC (14q11.2)
ZNF219 (14q11.2) / HNRNPC (14q11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HNRNPC   5035
Cards
Entrez_Gene (NCBI)HNRNPC  3183  heterogeneous nuclear ribonucleoprotein C (C1/C2)
AliasesC1; C2; HNRNP; HNRPC; 
SNRPC
GeneCards (Weizmann)HNRNPC
Ensembl hg19 (Hinxton)ENSG00000092199 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000092199 [Gene_View]  chr14:21209136-21269479 [Contig_View]  HNRNPC [Vega]
ICGC DataPortalENSG00000092199
TCGA cBioPortalHNRNPC
AceView (NCBI)HNRNPC
Genatlas (Paris)HNRNPC
WikiGenes3183
SOURCE (Princeton)HNRNPC
Genetics Home Reference (NIH)HNRNPC
Genomic and cartography
GoldenPath hg38 (UCSC)HNRNPC  -     chr14:21209136-21269479 -  14q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HNRNPC  -     14q11.2   [Description]    (hg19-Feb_2009)
EnsemblHNRNPC - 14q11.2 [CytoView hg19]  HNRNPC - 14q11.2 [CytoView hg38]
Mapping of homologs : NCBIHNRNPC [Mapview hg19]  HNRNPC [Mapview hg38]
OMIM164020   
Gene and transcription
Genbank (Entrez)###############################################################################################################################################################################################################################################################
RefSeq transcript (Entrez)NM_001077442 NM_001077443 NM_004500 NM_031314
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HNRNPC
Cluster EST : UnigeneHs.675546 [ NCBI ]
CGAP (NCI)Hs.675546
Alternative Splicing GalleryENSG00000092199
Gene ExpressionHNRNPC [ NCBI-GEO ]   HNRNPC [ EBI - ARRAY_EXPRESS ]   HNRNPC [ SEEK ]   HNRNPC [ MEM ]
Gene Expression Viewer (FireBrowse)HNRNPC [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3183
GTEX Portal (Tissue expression)HNRNPC
Protein : pattern, domain, 3D structure
UniProt/SwissProtP07910   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP07910  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP07910
Splice isoforms : SwissVarP07910
PhosPhoSitePlusP07910
Domaine pattern : Prosite (Expaxy)RRM (PS50102)   
Domains : Interpro (EBI)hnRNP_C    Nucleotide-bd_a/b_plait    RRM_dom   
Domain families : Pfam (Sanger)RRM_1 (PF00076)   
Domain families : Pfam (NCBI)pfam00076   
Domain families : Smart (EMBL)RRM (SM00360)  
Conserved Domain (NCBI)HNRNPC
DMDM Disease mutations3183
Blocks (Seattle)HNRNPC
PDB (SRS)1TXP    1WF2    2MXY    2MZ1    3LN4   
PDB (PDBSum)1TXP    1WF2    2MXY    2MZ1    3LN4   
PDB (IMB)1TXP    1WF2    2MXY    2MZ1    3LN4   
PDB (RSDB)1TXP    1WF2    2MXY    2MZ1    3LN4   
Structural Biology KnowledgeBase1TXP    1WF2    2MXY    2MZ1    3LN4   
SCOP (Structural Classification of Proteins)1TXP    1WF2    2MXY    2MZ1    3LN4   
CATH (Classification of proteins structures)1TXP    1WF2    2MXY    2MZ1    3LN4   
SuperfamilyP07910
Human Protein AtlasENSG00000092199
Peptide AtlasP07910
HPRD01243
IPI###############################################################################################################################################################################################################################################################   
Protein Interaction databases
DIP (DOE-UCLA)P07910
IntAct (EBI)P07910
FunCoupENSG00000092199
BioGRIDHNRNPC
STRING (EMBL)HNRNPC
ZODIACHNRNPC
Ontologies - Pathways
QuickGOP07910
Ontology : AmiGOmRNA splicing, via spliceosome  mRNA splicing, via spliceosome  mRNA splicing, via spliceosome  nuclear chromatin  RNA polymerase II core promoter proximal region sequence-specific DNA binding  RNA polymerase II distal enhancer sequence-specific DNA binding  osteoblast differentiation  RNA binding  RNA binding  mRNA 3'-UTR binding  protein binding  nucleus  nucleoplasm  nucleoplasm  spliceosomal complex  telomerase holoenzyme complex  cytosol  poly(U) RNA binding  RNA splicing  gene expression  membrane  nucleosomal DNA binding  negative regulation of telomere maintenance via telomerase  identical protein binding  ATP-dependent chromatin remodeling  protein complex  telomerase RNA binding  extracellular exosome  3'-UTR-mediated mRNA stabilization  catalytic step 2 spliceosome  N6-methyladenosine-containing RNA binding  
Ontology : EGO-EBImRNA splicing, via spliceosome  mRNA splicing, via spliceosome  mRNA splicing, via spliceosome  nuclear chromatin  RNA polymerase II core promoter proximal region sequence-specific DNA binding  RNA polymerase II distal enhancer sequence-specific DNA binding  osteoblast differentiation  RNA binding  RNA binding  mRNA 3'-UTR binding  protein binding  nucleus  nucleoplasm  nucleoplasm  spliceosomal complex  telomerase holoenzyme complex  cytosol  poly(U) RNA binding  RNA splicing  gene expression  membrane  nucleosomal DNA binding  negative regulation of telomere maintenance via telomerase  identical protein binding  ATP-dependent chromatin remodeling  protein complex  telomerase RNA binding  extracellular exosome  3'-UTR-mediated mRNA stabilization  catalytic step 2 spliceosome  N6-methyladenosine-containing RNA binding  
Pathways : KEGGSpliceosome   
NDEx NetworkHNRNPC
Atlas of Cancer Signalling NetworkHNRNPC
Wikipedia pathwaysHNRNPC
Orthology - Evolution
OrthoDB3183
GeneTree (enSembl)ENSG00000092199
Phylogenetic Trees/Animal Genes : TreeFamHNRNPC
HOVERGENP07910
HOGENOMP07910
Homologs : HomoloGeneHNRNPC
Homology/Alignments : Family Browser (UCSC)HNRNPC
Gene fusions - Rearrangements
Fusion : MitelmanHNRNPC/ZNF219 [14q11.2/14q11.2]  
Fusion : MitelmanZNF219/HNRNPC [14q11.2/14q11.2]  [t(14;14)(q11;q11)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHNRNPC [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HNRNPC
dbVarHNRNPC
ClinVarHNRNPC
1000_GenomesHNRNPC 
Exome Variant ServerHNRNPC
ExAC (Exome Aggregation Consortium)HNRNPC (select the gene name)
Genetic variants : HAPMAP3183
Genomic Variants (DGV)HNRNPC [DGVbeta]
DECIPHERHNRNPC [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHNRNPC 
Mutations
ICGC Data PortalHNRNPC 
TCGA Data PortalHNRNPC 
Broad Tumor PortalHNRNPC
OASIS PortalHNRNPC [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHNRNPC  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHNRNPC
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HNRNPC
DgiDB (Drug Gene Interaction Database)HNRNPC
DoCM (Curated mutations)HNRNPC (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HNRNPC (select a term)
intoGenHNRNPC
Cancer3DHNRNPC(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM164020   
Orphanet
MedgenHNRNPC
Genetic Testing Registry HNRNPC
NextProtP07910 [Medical]
TSGene3183
GENETestsHNRNPC
Huge Navigator HNRNPC [HugePedia]
snp3D : Map Gene to Disease3183
BioCentury BCIQHNRNPC
ClinGenHNRNPC
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3183
Chemical/Pharm GKB GenePA162391217
Clinical trialHNRNPC
Miscellaneous
canSAR (ICR)HNRNPC (select the gene name)
Probes
Litterature
PubMed171 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHNRNPC
EVEXHNRNPC
GoPubMedHNRNPC
iHOPHNRNPC
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:19:10 CEST 2017

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