Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HOGA1 (4-hydroxy-2-oxoglutarate aldolase 1)

Identity

Alias_namesC10orf65
DHDPSL
chromosome 10 open reading frame 65
dihydrodipicolinate synthase-like, mitochondrial
Alias_symbol (synonym)FLJ37472
DHDPS2
NPL2
Other aliasHP3
HGNC (Hugo) HOGA1
LocusID (NCBI) 112817
Atlas_Id 64378
Location 10q24.2  [Link to chromosome band 10q24]
Location_base_pair Starts at 97584345 and ends at 97612798 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
HOGA1 (10q24.2) / LOC100507412 (-)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HOGA1   25155
Cards
Entrez_Gene (NCBI)HOGA1  112817  4-hydroxy-2-oxoglutarate aldolase 1
AliasesC10orf65; DHDPS2; DHDPSL; HP3; 
NPL2
GeneCards (Weizmann)HOGA1
Ensembl hg19 (Hinxton)ENSG00000241935 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000241935 [Gene_View]  chr10:97584345-97612798 [Contig_View]  HOGA1 [Vega]
ICGC DataPortalENSG00000241935
TCGA cBioPortalHOGA1
AceView (NCBI)HOGA1
Genatlas (Paris)HOGA1
WikiGenes112817
SOURCE (Princeton)HOGA1
Genetics Home Reference (NIH)HOGA1
Genomic and cartography
GoldenPath hg38 (UCSC)HOGA1  -     chr10:97584345-97612798 +  10q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HOGA1  -     10q24.2   [Description]    (hg19-Feb_2009)
EnsemblHOGA1 - 10q24.2 [CytoView hg19]  HOGA1 - 10q24.2 [CytoView hg38]
Mapping of homologs : NCBIHOGA1 [Mapview hg19]  HOGA1 [Mapview hg38]
OMIM613597   613616   
Gene and transcription
Genbank (Entrez)AK094791 AK289440 BC011916 BC045550 BC057821
RefSeq transcript (Entrez)NM_001134670 NM_138413
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HOGA1
Cluster EST : UnigeneHs.180346 [ NCBI ]
CGAP (NCI)Hs.180346
Alternative Splicing GalleryENSG00000241935
Gene ExpressionHOGA1 [ NCBI-GEO ]   HOGA1 [ EBI - ARRAY_EXPRESS ]   HOGA1 [ SEEK ]   HOGA1 [ MEM ]
Gene Expression Viewer (FireBrowse)HOGA1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)112817
GTEX Portal (Tissue expression)HOGA1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86XE5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86XE5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86XE5
Splice isoforms : SwissVarQ86XE5
Catalytic activity : Enzyme4.1.3.16 [ Enzyme-Expasy ]   4.1.3.164.1.3.16 [ IntEnz-EBI ]   4.1.3.16 [ BRENDA ]   4.1.3.16 [ KEGG ]   
PhosPhoSitePlusQ86XE5
Domaine pattern : Prosite (Expaxy)DHDPS_2 (PS00666)   
Domains : Interpro (EBI)Aldolase_TIM    DapA-like    Schiff_base-form_aldolases_AS   
Domain families : Pfam (Sanger)DHDPS (PF00701)   
Domain families : Pfam (NCBI)pfam00701   
Domain families : Smart (EMBL)DHDPS (SM01130)  
Conserved Domain (NCBI)HOGA1
DMDM Disease mutations112817
Blocks (Seattle)HOGA1
PDB (SRS)3S5N    3S5O   
PDB (PDBSum)3S5N    3S5O   
PDB (IMB)3S5N    3S5O   
PDB (RSDB)3S5N    3S5O   
Structural Biology KnowledgeBase3S5N    3S5O   
SCOP (Structural Classification of Proteins)3S5N    3S5O   
CATH (Classification of proteins structures)3S5N    3S5O   
SuperfamilyQ86XE5
Human Protein AtlasENSG00000241935
Peptide AtlasQ86XE5
HPRD12584
IPIIPI00642544   IPI00061760   IPI00640572   
Protein Interaction databases
DIP (DOE-UCLA)Q86XE5
IntAct (EBI)Q86XE5
FunCoupENSG00000241935
BioGRIDHOGA1
STRING (EMBL)HOGA1
ZODIACHOGA1
Ontologies - Pathways
QuickGOQ86XE5
Ontology : AmiGOmitochondrion  4-hydroxy-2-oxoglutarate aldolase activity  4-hydroxy-2-oxoglutarate aldolase activity  glyoxylate catabolic process  4-hydroxyproline catabolic process  oxalate metabolic process  protein homodimerization activity  pyruvate biosynthetic process  glyoxylate metabolic process  extracellular exosome  
Ontology : EGO-EBImitochondrion  4-hydroxy-2-oxoglutarate aldolase activity  4-hydroxy-2-oxoglutarate aldolase activity  glyoxylate catabolic process  4-hydroxyproline catabolic process  oxalate metabolic process  protein homodimerization activity  pyruvate biosynthetic process  glyoxylate metabolic process  extracellular exosome  
NDEx NetworkHOGA1
Atlas of Cancer Signalling NetworkHOGA1
Wikipedia pathwaysHOGA1
Orthology - Evolution
OrthoDB112817
GeneTree (enSembl)ENSG00000241935
Phylogenetic Trees/Animal Genes : TreeFamHOGA1
HOVERGENQ86XE5
HOGENOMQ86XE5
Homologs : HomoloGeneHOGA1
Homology/Alignments : Family Browser (UCSC)HOGA1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHOGA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HOGA1
dbVarHOGA1
ClinVarHOGA1
1000_GenomesHOGA1 
Exome Variant ServerHOGA1
ExAC (Exome Aggregation Consortium)HOGA1 (select the gene name)
Genetic variants : HAPMAP112817
Genomic Variants (DGV)HOGA1 [DGVbeta]
DECIPHERHOGA1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHOGA1 
Mutations
ICGC Data PortalHOGA1 
TCGA Data PortalHOGA1 
Broad Tumor PortalHOGA1
OASIS PortalHOGA1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHOGA1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHOGA1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HOGA1
DgiDB (Drug Gene Interaction Database)HOGA1
DoCM (Curated mutations)HOGA1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HOGA1 (select a term)
intoGenHOGA1
Cancer3DHOGA1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613597    613616   
Orphanet12433   
MedgenHOGA1
Genetic Testing Registry HOGA1
NextProtQ86XE5 [Medical]
TSGene112817
GENETestsHOGA1
Target ValidationHOGA1
Huge Navigator HOGA1 [HugePedia]
snp3D : Map Gene to Disease112817
BioCentury BCIQHOGA1
ClinGenHOGA1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD112817
Chemical/Pharm GKB GenePA165548441
Clinical trialHOGA1
Miscellaneous
canSAR (ICR)HOGA1 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHOGA1
EVEXHOGA1
GoPubMedHOGA1
iHOPHOGA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 15:52:39 CEST 2017

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