Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HOMER1 (homer scaffolding protein 1)

Identity

Alias_nameshomer homolog 1 (Drosophila)
Alias_symbol (synonym)Ves-1
SYN47
HOMER-1B
Other aliasHOMER
HOMER1A
HOMER1B
HOMER1C
HGNC (Hugo) HOMER1
LocusID (NCBI) 9456
Atlas_Id 55049
Location 5q14.1  [Link to chromosome band 5q14]
Location_base_pair Starts at 79373824 and ends at 79513836 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
HOMER1 (5q14.1) / EFNB3 (17p13.1)HOMER1 (5q14.1) / MAST2 (1p34.1)HOMER1 (5q14.1) / SREK1 (5q12.3)
ITPR2 (12p12.1) / HOMER1 (5q14.1)SREK1 (5q12.3) / HOMER1 (5q14.1)HOMER1 5q14.1 / MAST2 1p34.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HOMER1   17512
Cards
Entrez_Gene (NCBI)HOMER1  9456  homer scaffolding protein 1
AliasesHOMER; HOMER1A; HOMER1B; HOMER1C; 
SYN47; Ves-1
GeneCards (Weizmann)HOMER1
Ensembl hg19 (Hinxton)ENSG00000152413 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000152413 [Gene_View]  chr5:79373824-79513836 [Contig_View]  HOMER1 [Vega]
ICGC DataPortalENSG00000152413
TCGA cBioPortalHOMER1
AceView (NCBI)HOMER1
Genatlas (Paris)HOMER1
WikiGenes9456
SOURCE (Princeton)HOMER1
Genetics Home Reference (NIH)HOMER1
Genomic and cartography
GoldenPath hg38 (UCSC)HOMER1  -     chr5:79373824-79513836 -  5q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HOMER1  -     5q14.1   [Description]    (hg19-Feb_2009)
EnsemblHOMER1 - 5q14.1 [CytoView hg19]  HOMER1 - 5q14.1 [CytoView hg38]
Mapping of homologs : NCBIHOMER1 [Mapview hg19]  HOMER1 [Mapview hg38]
OMIM604798   
Gene and transcription
Genbank (Entrez)AA029302 AF093262 AK223471 AK312481 AY189939
RefSeq transcript (Entrez)NM_001277077 NM_001277078 NM_004272
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HOMER1
Cluster EST : UnigeneHs.591761 [ NCBI ]
CGAP (NCI)Hs.591761
Alternative Splicing GalleryENSG00000152413
Gene ExpressionHOMER1 [ NCBI-GEO ]   HOMER1 [ EBI - ARRAY_EXPRESS ]   HOMER1 [ SEEK ]   HOMER1 [ MEM ]
Gene Expression Viewer (FireBrowse)HOMER1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9456
GTEX Portal (Tissue expression)HOMER1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86YM7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86YM7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86YM7
Splice isoforms : SwissVarQ86YM7
PhosPhoSitePlusQ86YM7
Domaine pattern : Prosite (Expaxy)WH1 (PS50229)   
Domains : Interpro (EBI)PH_dom-like    WH1/EVH1_dom   
Domain families : Pfam (Sanger)WH1 (PF00568)   
Domain families : Pfam (NCBI)pfam00568   
Domain families : Smart (EMBL)WH1 (SM00461)  
Conserved Domain (NCBI)HOMER1
DMDM Disease mutations9456
Blocks (Seattle)HOMER1
SuperfamilyQ86YM7
Human Protein AtlasENSG00000152413
Peptide AtlasQ86YM7
HPRD09211
IPIIPI00003566   IPI00384726   IPI00394997   IPI01012791   
Protein Interaction databases
DIP (DOE-UCLA)Q86YM7
IntAct (EBI)Q86YM7
FunCoupENSG00000152413
BioGRIDHOMER1
STRING (EMBL)HOMER1
ZODIACHOMER1
Ontologies - Pathways
QuickGOQ86YM7
Ontology : AmiGOskeletal muscle contraction  protein binding  cytosol  phospholipase C-activating G-protein coupled glutamate receptor signaling pathway  chemical synaptic transmission  positive regulation of signal transduction  postsynaptic density  Z disc  cell junction  axon  signaling adaptor activity  costamere  ion channel binding  apical part of cell  postsynaptic membrane  behavioral response to cocaine  skeletal muscle fiber development  chemical homeostasis within a tissue  response to calcium ion  positive regulation of calcium ion transport  regulation of calcium ion import  regulation of store-operated calcium entry  regulation of cation channel activity  
Ontology : EGO-EBIskeletal muscle contraction  protein binding  cytosol  phospholipase C-activating G-protein coupled glutamate receptor signaling pathway  chemical synaptic transmission  positive regulation of signal transduction  postsynaptic density  Z disc  cell junction  axon  signaling adaptor activity  costamere  ion channel binding  apical part of cell  postsynaptic membrane  behavioral response to cocaine  skeletal muscle fiber development  chemical homeostasis within a tissue  response to calcium ion  positive regulation of calcium ion transport  regulation of calcium ion import  regulation of store-operated calcium entry  regulation of cation channel activity  
Pathways : KEGGFoxO signaling pathway    Glutamatergic synapse   
NDEx NetworkHOMER1
Atlas of Cancer Signalling NetworkHOMER1
Wikipedia pathwaysHOMER1
Orthology - Evolution
OrthoDB9456
GeneTree (enSembl)ENSG00000152413
Phylogenetic Trees/Animal Genes : TreeFamHOMER1
HOVERGENQ86YM7
HOGENOMQ86YM7
Homologs : HomoloGeneHOMER1
Homology/Alignments : Family Browser (UCSC)HOMER1
Gene fusions - Rearrangements
Fusion : MitelmanHOMER1/MAST2 [5q14.1/1p34.1]  
Fusion: TCGAHOMER1 5q14.1 MAST2 1p34.1 LGG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHOMER1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HOMER1
dbVarHOMER1
ClinVarHOMER1
1000_GenomesHOMER1 
Exome Variant ServerHOMER1
ExAC (Exome Aggregation Consortium)HOMER1 (select the gene name)
Genetic variants : HAPMAP9456
Genomic Variants (DGV)HOMER1 [DGVbeta]
DECIPHERHOMER1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHOMER1 
Mutations
ICGC Data PortalHOMER1 
TCGA Data PortalHOMER1 
Broad Tumor PortalHOMER1
OASIS PortalHOMER1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHOMER1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHOMER1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HOMER1
DgiDB (Drug Gene Interaction Database)HOMER1
DoCM (Curated mutations)HOMER1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HOMER1 (select a term)
intoGenHOMER1
Cancer3DHOMER1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604798   
Orphanet
MedgenHOMER1
Genetic Testing Registry HOMER1
NextProtQ86YM7 [Medical]
TSGene9456
GENETestsHOMER1
Target ValidationHOMER1
Huge Navigator HOMER1 [HugePedia]
snp3D : Map Gene to Disease9456
BioCentury BCIQHOMER1
ClinGenHOMER1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9456
Chemical/Pharm GKB GenePA134972608
Clinical trialHOMER1
Miscellaneous
canSAR (ICR)HOMER1 (select the gene name)
Probes
Litterature
PubMed63 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHOMER1
EVEXHOMER1
GoPubMedHOMER1
iHOPHOMER1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:55:34 CEST 2017

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