Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HOMER2 (homer scaffolding protein 2)

Identity

Alias_nameshomer homolog 2 (Drosophila)
Alias_symbol (synonym)CPD
Cupidin
Vesl-2
HOMER-2B
HOMER-2
HOMER-2A
Other aliasACPD
DFNA68
VESL-2
HGNC (Hugo) HOMER2
LocusID (NCBI) 9455
Atlas_Id 64380
Location 15q25.2  [Link to chromosome band 15q25]
Location_base_pair Starts at 82848977 and ends at 82952724 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CHD2 (15q26.1) / HOMER2 (15q25.2)RASGRF1 (15q25.1) / HOMER2 (15q25.2)CHD2 HOMER2
RASGRF1 HOMER2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HOMER2   17513
Cards
Entrez_Gene (NCBI)HOMER2  9455  homer scaffolding protein 2
AliasesACPD; CPD; DFNA68; HOMER-2; 
VESL-2
GeneCards (Weizmann)HOMER2
Ensembl hg19 (Hinxton)ENSG00000103942 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000103942 [Gene_View]  chr15:82848977-82952724 [Contig_View]  HOMER2 [Vega]
ICGC DataPortalENSG00000103942
TCGA cBioPortalHOMER2
AceView (NCBI)HOMER2
Genatlas (Paris)HOMER2
WikiGenes9455
SOURCE (Princeton)HOMER2
Genetics Home Reference (NIH)HOMER2
Genomic and cartography
GoldenPath hg38 (UCSC)HOMER2  -     chr15:82848977-82952724 -  15q25.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HOMER2  -     15q25.2   [Description]    (hg19-Feb_2009)
EnsemblHOMER2 - 15q25.2 [CytoView hg19]  HOMER2 - 15q25.2 [CytoView hg38]
Mapping of homologs : NCBIHOMER2 [Mapview hg19]  HOMER2 [Mapview hg38]
OMIM604799   616707   
Gene and transcription
Genbank (Entrez)AF081530 AF093263 AF093264 AK292772 AY062316
RefSeq transcript (Entrez)NM_004839 NM_199330 NM_199331 NM_199332
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HOMER2
Cluster EST : UnigeneHs.736981 [ NCBI ]
CGAP (NCI)Hs.736981
Alternative Splicing GalleryENSG00000103942
Gene ExpressionHOMER2 [ NCBI-GEO ]   HOMER2 [ EBI - ARRAY_EXPRESS ]   HOMER2 [ SEEK ]   HOMER2 [ MEM ]
Gene Expression Viewer (FireBrowse)HOMER2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9455
GTEX Portal (Tissue expression)HOMER2
Human Protein AtlasENSG00000103942-HOMER2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NSB8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NSB8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NSB8
Splice isoforms : SwissVarQ9NSB8
PhosPhoSitePlusQ9NSB8
Domaine pattern : Prosite (Expaxy)WH1 (PS50229)   
Domains : Interpro (EBI)PH_dom-like    WH1/EVH1_dom   
Domain families : Pfam (Sanger)WH1 (PF00568)   
Domain families : Pfam (NCBI)pfam00568   
Domain families : Smart (EMBL)WH1 (SM00461)  
Conserved Domain (NCBI)HOMER2
DMDM Disease mutations9455
Blocks (Seattle)HOMER2
SuperfamilyQ9NSB8
Human Protein Atlas [tissue]ENSG00000103942-HOMER2 [tissue]
Peptide AtlasQ9NSB8
HPRD07269
IPIIPI00394745   IPI00394746   IPI00784182   IPI00784456   
Protein Interaction databases
DIP (DOE-UCLA)Q9NSB8
IntAct (EBI)Q9NSB8
FunCoupENSG00000103942
BioGRIDHOMER2
STRING (EMBL)HOMER2
ZODIACHOMER2
Ontologies - Pathways
QuickGOQ9NSB8
Ontology : AmiGOactin binding  protein binding  cytoplasm  cytosol  cytosol  G-protein coupled glutamate receptor signaling pathway  sensory perception of sound  regulation of G-protein coupled receptor protein signaling pathway  postsynaptic density  protein domain specific binding  cell junction  GKAP/Homer scaffold activity  dendrite  stereocilium tip  G-protein coupled glutamate receptor binding  calcium-mediated signaling using intracellular calcium source  protein homodimerization activity  neuronal cell body  apical part of cell  postsynaptic membrane  protein heterodimerization activity  behavioral response to cocaine  chemical homeostasis within a tissue  
Ontology : EGO-EBIactin binding  protein binding  cytoplasm  cytosol  cytosol  G-protein coupled glutamate receptor signaling pathway  sensory perception of sound  regulation of G-protein coupled receptor protein signaling pathway  postsynaptic density  protein domain specific binding  cell junction  GKAP/Homer scaffold activity  dendrite  stereocilium tip  G-protein coupled glutamate receptor binding  calcium-mediated signaling using intracellular calcium source  protein homodimerization activity  neuronal cell body  apical part of cell  postsynaptic membrane  protein heterodimerization activity  behavioral response to cocaine  chemical homeostasis within a tissue  
Pathways : KEGGFoxO signaling pathway    Glutamatergic synapse   
NDEx NetworkHOMER2
Atlas of Cancer Signalling NetworkHOMER2
Wikipedia pathwaysHOMER2
Orthology - Evolution
OrthoDB9455
GeneTree (enSembl)ENSG00000103942
Phylogenetic Trees/Animal Genes : TreeFamHOMER2
HOVERGENQ9NSB8
HOGENOMQ9NSB8
Homologs : HomoloGeneHOMER2
Homology/Alignments : Family Browser (UCSC)HOMER2
Gene fusions - Rearrangements
Fusion: TCGACHD2 HOMER2
Fusion: TCGARASGRF1 HOMER2
Fusion: Tumor Portal HOMER2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHOMER2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HOMER2
dbVarHOMER2
ClinVarHOMER2
1000_GenomesHOMER2 
Exome Variant ServerHOMER2
ExAC (Exome Aggregation Consortium)ENSG00000103942
GNOMAD BrowserENSG00000103942
Genetic variants : HAPMAP9455
Genomic Variants (DGV)HOMER2 [DGVbeta]
DECIPHERHOMER2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHOMER2 
Mutations
ICGC Data PortalHOMER2 
TCGA Data PortalHOMER2 
Broad Tumor PortalHOMER2
OASIS PortalHOMER2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHOMER2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHOMER2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HOMER2
DgiDB (Drug Gene Interaction Database)HOMER2
DoCM (Curated mutations)HOMER2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HOMER2 (select a term)
intoGenHOMER2
Cancer3DHOMER2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604799    616707   
Orphanet12046   
MedgenHOMER2
Genetic Testing Registry HOMER2
NextProtQ9NSB8 [Medical]
TSGene9455
GENETestsHOMER2
Target ValidationHOMER2
Huge Navigator HOMER2 [HugePedia]
snp3D : Map Gene to Disease9455
BioCentury BCIQHOMER2
ClinGenHOMER2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9455
Chemical/Pharm GKB GenePA134870500
Clinical trialHOMER2
Miscellaneous
canSAR (ICR)HOMER2 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHOMER2
EVEXHOMER2
GoPubMedHOMER2
iHOPHOMER2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Nov 9 11:50:50 CET 2017

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