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HOPX (HOP homeobox)

Identity

Alias_symbol (synonym)LAGY
HOP
OB1
NECC1
SMAP31
Other aliasCAMEO
HOD
TOTO
HGNC (Hugo) HOPX
LocusID (NCBI) 84525
Atlas_Id 40845
Location 4q12  [Link to chromosome band 4q12]
Location_base_pair Starts at 56647988 and ends at 56656522 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
HOPX (4q12) / PDCL2 (4q12)SH3KBP1 (Xp22.12) / HOPX (4q12)TPM1 (15q22.2) / HOPX (4q12)
HOPX 4q12 / PDCL2 4q12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HOPX   24961
Cards
Entrez_Gene (NCBI)HOPX  84525  HOP homeobox
AliasesCAMEO; HOD; HOP; LAGY; 
NECC1; OB1; SMAP31; TOTO
GeneCards (Weizmann)HOPX
Ensembl hg19 (Hinxton)ENSG00000171476 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171476 [Gene_View]  chr4:56647988-56656522 [Contig_View]  HOPX [Vega]
ICGC DataPortalENSG00000171476
TCGA cBioPortalHOPX
AceView (NCBI)HOPX
Genatlas (Paris)HOPX
WikiGenes84525
SOURCE (Princeton)HOPX
Genetics Home Reference (NIH)HOPX
Genomic and cartography
GoldenPath hg38 (UCSC)HOPX  -     chr4:56647988-56656522 -  4q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HOPX  -     4q12   [Description]    (hg19-Feb_2009)
EnsemblHOPX - 4q12 [CytoView hg19]  HOPX - 4q12 [CytoView hg38]
Mapping of homologs : NCBIHOPX [Mapview hg19]  HOPX [Mapview hg38]
OMIM607275   
Gene and transcription
Genbank (Entrez)AA504137 AB019573 AB059408 AB059409 AB059410
RefSeq transcript (Entrez)NM_001145459 NM_001145460 NM_032495 NM_139211 NM_139212
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HOPX
Cluster EST : UnigeneHs.619396 [ NCBI ]
CGAP (NCI)Hs.619396
Alternative Splicing GalleryENSG00000171476
Gene ExpressionHOPX [ NCBI-GEO ]   HOPX [ EBI - ARRAY_EXPRESS ]   HOPX [ SEEK ]   HOPX [ MEM ]
Gene Expression Viewer (FireBrowse)HOPX [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84525
GTEX Portal (Tissue expression)HOPX
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BPY8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BPY8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BPY8
Splice isoforms : SwissVarQ9BPY8
PhosPhoSitePlusQ9BPY8
Domaine pattern : Prosite (Expaxy)HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_dom   
Domain families : Pfam (Sanger)Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)HOPX
DMDM Disease mutations84525
Blocks (Seattle)HOPX
SuperfamilyQ9BPY8
Human Protein AtlasENSG00000171476
Peptide AtlasQ9BPY8
HPRD06280
IPIIPI00386436   IPI00876964   IPI00166087   IPI01024964   IPI00940156   IPI00658087   
Protein Interaction databases
DIP (DOE-UCLA)Q9BPY8
IntAct (EBI)Q9BPY8
FunCoupENSG00000171476
BioGRIDHOPX
STRING (EMBL)HOPX
ZODIACHOPX
Ontologies - Pathways
QuickGOQ9BPY8
Ontology : AmiGOtrophectodermal cell differentiation  DNA binding  protein binding  nucleus  cytoplasm  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  negative regulation of cell differentiation  chaperone-mediated protein complex assembly  
Ontology : EGO-EBItrophectodermal cell differentiation  DNA binding  protein binding  nucleus  cytoplasm  transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  negative regulation of cell differentiation  chaperone-mediated protein complex assembly  
Pathways : BIOCARTAHop Pathway in Cardiac Development [Genes]   
NDEx NetworkHOPX
Atlas of Cancer Signalling NetworkHOPX
Wikipedia pathwaysHOPX
Orthology - Evolution
OrthoDB84525
GeneTree (enSembl)ENSG00000171476
Phylogenetic Trees/Animal Genes : TreeFamHOPX
HOVERGENQ9BPY8
HOGENOMQ9BPY8
Homologs : HomoloGeneHOPX
Homology/Alignments : Family Browser (UCSC)HOPX
Gene fusions - Rearrangements
Fusion: TCGAHOPX 4q12 PDCL2 4q12 GBM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHOPX [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HOPX
dbVarHOPX
ClinVarHOPX
1000_GenomesHOPX 
Exome Variant ServerHOPX
ExAC (Exome Aggregation Consortium)HOPX (select the gene name)
Genetic variants : HAPMAP84525
Genomic Variants (DGV)HOPX [DGVbeta]
DECIPHERHOPX [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHOPX 
Mutations
ICGC Data PortalHOPX 
TCGA Data PortalHOPX 
Broad Tumor PortalHOPX
OASIS PortalHOPX [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHOPX  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHOPX
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HOPX
DgiDB (Drug Gene Interaction Database)HOPX
DoCM (Curated mutations)HOPX (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HOPX (select a term)
intoGenHOPX
Cancer3DHOPX(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607275   
Orphanet
MedgenHOPX
Genetic Testing Registry HOPX
NextProtQ9BPY8 [Medical]
TSGene84525
GENETestsHOPX
Target ValidationHOPX
Huge Navigator HOPX [HugePedia]
snp3D : Map Gene to Disease84525
BioCentury BCIQHOPX
ClinGenHOPX
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84525
Chemical/Pharm GKB GenePA162391564
Clinical trialHOPX
Miscellaneous
canSAR (ICR)HOPX (select the gene name)
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHOPX
EVEXHOPX
GoPubMedHOPX
iHOPHOPX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:12:01 CEST 2017

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