Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

HOPX (HOP homeobox)

Identity

Alias (NCBI)CAMEO
HOD
HOP
LAGY
NECC1
OB1
SMAP31
TOTO
HGNC (Hugo) HOPX
HGNC Alias symbLAGY
HOP
OB1
NECC1
SMAP31
HGNC Alias namehomeobox only domain
LocusID (NCBI) 84525
Atlas_Id 40845
Location 4q12  [Link to chromosome band 4q12]
Location_base_pair Starts at 56647988 and ends at 56681706 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HOPX (4q12) / PDCL2 (4q12)SH3KBP1 (Xp22.12) / HOPX (4q12)TPM1 (15q22.2) / HOPX (4q12)
HOPX 4q12 / PDCL2 4q12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)HOPX   24961
Cards
Entrez_Gene (NCBI)HOPX    HOP homeobox
AliasesCAMEO; HOD; HOP; LAGY; 
NECC1; OB1; SMAP31; TOTO
GeneCards (Weizmann)HOPX
Ensembl hg19 (Hinxton)ENSG00000171476 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171476 [Gene_View]  ENSG00000171476 [Sequence]  chr4:56647988-56681706 [Contig_View]  HOPX [Vega]
ICGC DataPortalENSG00000171476
TCGA cBioPortalHOPX
AceView (NCBI)HOPX
Genatlas (Paris)HOPX
SOURCE (Princeton)HOPX
Genetics Home Reference (NIH)HOPX
Genomic and cartography
GoldenPath hg38 (UCSC)HOPX  -     chr4:56647988-56681706 -  4q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HOPX  -     4q12   [Description]    (hg19-Feb_2009)
GoldenPathHOPX - 4q12 [CytoView hg19]  HOPX - 4q12 [CytoView hg38]
ImmunoBaseENSG00000171476
Genome Data Viewer NCBIHOPX [Mapview hg19]  
OMIM607275   
Gene and transcription
Genbank (Entrez)AA504137 AB019573 AB059408 AB059409 AB059410
RefSeq transcript (Entrez)NM_001145459 NM_001145460 NM_032495 NM_139211 NM_139212
Consensus coding sequences : CCDS (NCBI)HOPX
Gene ExpressionHOPX [ NCBI-GEO ]   HOPX [ EBI - ARRAY_EXPRESS ]   HOPX [ SEEK ]   HOPX [ MEM ]
Gene Expression Viewer (FireBrowse)HOPX [ Firebrowse - Broad ]
GenevisibleExpression of HOPX in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84525
GTEX Portal (Tissue expression)HOPX
Human Protein AtlasENSG00000171476-HOPX [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BPY8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BPY8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BPY8
PhosPhoSitePlusQ9BPY8
Domaine pattern : Prosite (Expaxy)HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like_sf    Homeobox_dom    HOPX   
Domain families : Pfam (Sanger)Homeodomain (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)HOPX
SuperfamilyQ9BPY8
AlphaFold pdb e-kbQ9BPY8   
Human Protein Atlas [tissue]ENSG00000171476-HOPX [tissue]
HPRD06280
Protein Interaction databases
DIP (DOE-UCLA)Q9BPY8
IntAct (EBI)Q9BPY8
BioGRIDHOPX
STRING (EMBL)HOPX
ZODIACHOPX
Ontologies - Pathways
QuickGOQ9BPY8
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  chromatin  trophectodermal cell differentiation  bundle of His development  DNA binding  protein binding  nucleus  nucleus  cytoplasm  regulation of transcription by RNA polymerase II  regulation of heart contraction  histone deacetylation  regulation of protein binding  positive regulation of skeletal muscle tissue regeneration  negative regulation of cell differentiation  lung alveolus development  chaperone-mediated protein complex assembly  positive regulation of striated muscle cell differentiation  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  chromatin  trophectodermal cell differentiation  bundle of His development  DNA binding  protein binding  nucleus  nucleus  cytoplasm  regulation of transcription by RNA polymerase II  regulation of heart contraction  histone deacetylation  regulation of protein binding  positive regulation of skeletal muscle tissue regeneration  negative regulation of cell differentiation  lung alveolus development  chaperone-mediated protein complex assembly  positive regulation of striated muscle cell differentiation  
Pathways : BIOCARTAHop Pathway in Cardiac Development [Genes]   
NDEx NetworkHOPX
Atlas of Cancer Signalling NetworkHOPX
Wikipedia pathwaysHOPX
Orthology - Evolution
OrthoDB84525
GeneTree (enSembl)ENSG00000171476
Phylogenetic Trees/Animal Genes : TreeFamHOPX
Homologs : HomoloGeneHOPX
Homology/Alignments : Family Browser (UCSC)HOPX
Gene fusions - Rearrangements
Fusion : QuiverHOPX
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHOPX [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HOPX
dbVarHOPX
ClinVarHOPX
MonarchHOPX
1000_GenomesHOPX 
Exome Variant ServerHOPX
GNOMAD BrowserENSG00000171476
Varsome BrowserHOPX
ACMGHOPX variants
VarityQ9BPY8
Genomic Variants (DGV)HOPX [DGVbeta]
DECIPHERHOPX [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHOPX 
Mutations
ICGC Data PortalHOPX 
TCGA Data PortalHOPX 
Broad Tumor PortalHOPX
OASIS PortalHOPX [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHOPX  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DHOPX
Mutations and Diseases : HGMDHOPX
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaHOPX
DgiDB (Drug Gene Interaction Database)HOPX
DoCM (Curated mutations)HOPX
CIViC (Clinical Interpretations of Variants in Cancer)HOPX
Cancer3DHOPX
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607275   
Orphanet
DisGeNETHOPX
MedgenHOPX
Genetic Testing Registry HOPX
NextProtQ9BPY8 [Medical]
GENETestsHOPX
Target ValidationHOPX
Huge Navigator HOPX [HugePedia]
ClinGenHOPX
Clinical trials, drugs, therapy
MyCancerGenomeHOPX
Protein Interactions : CTDHOPX
Pharm GKB GenePA162391564
PharosQ9BPY8
Clinical trialHOPX
Miscellaneous
canSAR (ICR)HOPX
HarmonizomeHOPX
DataMed IndexHOPX
Probes
Litterature
PubMed65 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXHOPX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:12:44 CEST 2021

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.