Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

HORMAD1 (HORMA domain containing 1)

Identity

Alias_symbol (synonym)DKFZP434A1315
CT46
Other aliasNOHMA
HGNC (Hugo) HORMAD1
LocusID (NCBI) 84072
Atlas_Id 53261
Location 1q21.3  [Link to chromosome band 1q21]
Location_base_pair Starts at 150698059 and ends at 150720888 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GOLPH3L (1q21.3) / HORMAD1 (1q21.3)UBXN2A (2p23.3) / HORMAD1 (1q21.3)XPO1 (2p15) / HORMAD1 (1q21.3)
GOLPH3L 1q21.3 / HORMAD1 1q21.3XPO1 2p15 / HORMAD1 1q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 3 ]
  t(1;1)(q21;q21) GOLPH3L/HORMAD1
t(1;1)(q21;q21) GOLPH3L/HORMAD1
t(1;2)(q21;p15) XPO1/HORMAD1


External links

Nomenclature
HGNC (Hugo)HORMAD1   25245
Cards
Entrez_Gene (NCBI)HORMAD1  84072  HORMA domain containing 1
AliasesCT46; NOHMA
GeneCards (Weizmann)HORMAD1
Ensembl hg19 (Hinxton)ENSG00000143452 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000143452 [Gene_View]  chr1:150698059-150720888 [Contig_View]  HORMAD1 [Vega]
ICGC DataPortalENSG00000143452
TCGA cBioPortalHORMAD1
AceView (NCBI)HORMAD1
Genatlas (Paris)HORMAD1
WikiGenes84072
SOURCE (Princeton)HORMAD1
Genetics Home Reference (NIH)HORMAD1
Genomic and cartography
GoldenPath hg38 (UCSC)HORMAD1  -     chr1:150698059-150720888 -  1q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HORMAD1  -     1q21.3   [Description]    (hg19-Feb_2009)
EnsemblHORMAD1 - 1q21.3 [CytoView hg19]  HORMAD1 - 1q21.3 [CytoView hg38]
Mapping of homologs : NCBIHORMAD1 [Mapview hg19]  HORMAD1 [Mapview hg38]
OMIM609824   
Gene and transcription
Genbank (Entrez)AA991355 AK097390 AK098633 AL136755 AY626344
RefSeq transcript (Entrez)NM_001199829 NM_032132
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HORMAD1
Cluster EST : UnigeneHs.298312 [ NCBI ]
CGAP (NCI)Hs.298312
Alternative Splicing GalleryENSG00000143452
Gene ExpressionHORMAD1 [ NCBI-GEO ]   HORMAD1 [ EBI - ARRAY_EXPRESS ]   HORMAD1 [ SEEK ]   HORMAD1 [ MEM ]
Gene Expression Viewer (FireBrowse)HORMAD1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84072
GTEX Portal (Tissue expression)HORMAD1
Human Protein AtlasENSG00000143452-HORMAD1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86X24   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86X24  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86X24
Splice isoforms : SwissVarQ86X24
PhosPhoSitePlusQ86X24
Domaine pattern : Prosite (Expaxy)HORMA (PS50815)   
Domains : Interpro (EBI)HORMA_dom   
Domain families : Pfam (Sanger)HORMA (PF02301)   
Domain families : Pfam (NCBI)pfam02301   
Conserved Domain (NCBI)HORMAD1
DMDM Disease mutations84072
Blocks (Seattle)HORMAD1
SuperfamilyQ86X24
Human Protein Atlas [tissue]ENSG00000143452-HORMAD1 [tissue]
Peptide AtlasQ86X24
HPRD11396
IPIIPI00640365   IPI00646171   IPI00643705   IPI00329515   IPI00643187   IPI00854823   
Protein Interaction databases
DIP (DOE-UCLA)Q86X24
IntAct (EBI)Q86X24
FunCoupENSG00000143452
BioGRIDHORMAD1
STRING (EMBL)HORMAD1
ZODIACHORMAD1
Ontologies - Pathways
QuickGOQ86X24
Ontology : AmiGOsynaptonemal complex  blastocyst development  nucleus  chromosome  synaptonemal complex assembly  spermatogenesis  meiotic DNA double-strand break formation  oogenesis  meiotic sister chromatid cohesion  meiotic cell cycle  meiotic recombination checkpoint  regulation of homologous chromosome segregation  
Ontology : EGO-EBIsynaptonemal complex  blastocyst development  nucleus  chromosome  synaptonemal complex assembly  spermatogenesis  meiotic DNA double-strand break formation  oogenesis  meiotic sister chromatid cohesion  meiotic cell cycle  meiotic recombination checkpoint  regulation of homologous chromosome segregation  
NDEx NetworkHORMAD1
Atlas of Cancer Signalling NetworkHORMAD1
Wikipedia pathwaysHORMAD1
Orthology - Evolution
OrthoDB84072
GeneTree (enSembl)ENSG00000143452
Phylogenetic Trees/Animal Genes : TreeFamHORMAD1
HOVERGENQ86X24
HOGENOMQ86X24
Homologs : HomoloGeneHORMAD1
Homology/Alignments : Family Browser (UCSC)HORMAD1
Gene fusions - Rearrangements
Fusion : MitelmanGOLPH3L/HORMAD1 [1q21.3/1q21.3]  [t(1;1)(q21;q21)]  
Fusion : MitelmanXPO1/HORMAD1 [2p15/1q21.3]  [t(1;2)(q21;p15)]  
Fusion: TCGA_MDACCGOLPH3L 1q21.3 HORMAD1 1q21.3 OV
Fusion: TCGA_MDACCXPO1 2p15 HORMAD1 1q21.3 BRCA
Fusion PortalGOLPH3L 1q21.3 HORMAD1 1q21.3 OV
Fusion PortalXPO1 2p15 HORMAD1 1q21.3 BRCA
Fusion : QuiverHORMAD1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHORMAD1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HORMAD1
dbVarHORMAD1
ClinVarHORMAD1
1000_GenomesHORMAD1 
Exome Variant ServerHORMAD1
ExAC (Exome Aggregation Consortium)ENSG00000143452
GNOMAD BrowserENSG00000143452
Genetic variants : HAPMAP84072
Genomic Variants (DGV)HORMAD1 [DGVbeta]
DECIPHERHORMAD1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHORMAD1 
Mutations
ICGC Data PortalHORMAD1 
TCGA Data PortalHORMAD1 
Broad Tumor PortalHORMAD1
OASIS PortalHORMAD1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHORMAD1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHORMAD1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HORMAD1
DgiDB (Drug Gene Interaction Database)HORMAD1
DoCM (Curated mutations)HORMAD1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HORMAD1 (select a term)
intoGenHORMAD1
Cancer3DHORMAD1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609824   
Orphanet
DisGeNETHORMAD1
MedgenHORMAD1
Genetic Testing Registry HORMAD1
NextProtQ86X24 [Medical]
TSGene84072
GENETestsHORMAD1
Target ValidationHORMAD1
Huge Navigator HORMAD1 [HugePedia]
snp3D : Map Gene to Disease84072
BioCentury BCIQHORMAD1
ClinGenHORMAD1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84072
Chemical/Pharm GKB GenePA134930374
Clinical trialHORMAD1
Miscellaneous
canSAR (ICR)HORMAD1 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHORMAD1
EVEXHORMAD1
GoPubMedHORMAD1
iHOPHORMAD1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Feb 28 13:16:34 CET 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.