HOXA10 (homeobox A10)

2003-02-01  

Identity

HGNC
LOCATION
7p15.2
LOCUSID
ALIAS
HOX1,HOX1.8,HOX1H,PL
FUSION GENES

Other Information

Locus ID:

NCBI: 3206
MIM: 142957
HGNC: 5100
Ensembl: ENSG00000253293

Variants:

dbSNP: 3206
ClinVar: 3206
TCGA: ENSG00000253293
COSMIC: HOXA10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000253293ENST00000283921P31260
ENSG00000253293ENST00000396344P31260
ENSG00000253293ENST00000613671Q5I0Y5

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Transcriptional misregulation in cancerKEGGko05202
Transcriptional misregulation in cancerKEGGhsa05202

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
160988582005Aberrant methylation at HOXA10 may be responsible for its aberrant expression in the endometrium of patients with endometriosis.60
118751172002Direct regulation of beta3-integrin subunit gene expression by HOXA10 in endometrial cells.58
209352182010MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase-mediated HOX/stem cell gene signature.57
208210452010The role of the Hoxa10/HOXA10 gene in the etiology of endometriosis and its related infertility: a review.38
219564272011MicroRNA 135 regulates HOXA10 expression in endometriosis.38
125198592003Regulation of HOXA-10 expression by testosterone in vitro and in the endometrium of patients with polycystic ovary syndrome.37
124829562003Transcriptional repression of peri-implantation EMX2 expression in mammalian reproduction by HOXA10.34
256228212015Chromosome 7 gain and DNA hypermethylation at the HOXA10 locus are associated with expression of a stem cell related HOX-signature in glioblastoma.34
174399482007Identification of a HoxA10 activation domain necessary for transcription of the gene encoding beta3 integrin during myeloid differentiation.32
124936912003Regulation of insulin-like growth factor binding protein-1 promoter activity by FKHR and HOXA10 in primate endometrial cells.31

Citation

Dessen P

HOXA10 (homeobox A10)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40846/hoxa10