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HOXA2 (homeobox A2)

Identity

Alias_namesHOX1K
homeo box A2
Other aliasMCOHI
HGNC (Hugo) HOXA2
LocusID (NCBI) 3199
Atlas_Id 64387
Location 7p15.2  [Link to chromosome band 7p15]
Location_base_pair Starts at 27100354 and ends at 27102775 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HOXA2   5103
Cards
Entrez_Gene (NCBI)HOXA2  3199  homeobox A2
AliasesHOX1K; MCOHI
GeneCards (Weizmann)HOXA2
Ensembl hg19 (Hinxton)ENSG00000105996 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105996 [Gene_View]  chr7:27100354-27102775 [Contig_View]  HOXA2 [Vega]
ICGC DataPortalENSG00000105996
TCGA cBioPortalHOXA2
AceView (NCBI)HOXA2
Genatlas (Paris)HOXA2
WikiGenes3199
SOURCE (Princeton)HOXA2
Genetics Home Reference (NIH)HOXA2
Genomic and cartography
GoldenPath hg38 (UCSC)HOXA2  -     chr7:27100354-27102775 -  7p15.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HOXA2  -     7p15.2   [Description]    (hg19-Feb_2009)
EnsemblHOXA2 - 7p15.2 [CytoView hg19]  HOXA2 - 7p15.2 [CytoView hg38]
Mapping of homologs : NCBIHOXA2 [Mapview hg19]  HOXA2 [Mapview hg38]
OMIM604685   612290   
Gene and transcription
Genbank (Entrez)AI581335 AI796505 AK096742 AK291164 AL079274
RefSeq transcript (Entrez)NM_006735
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HOXA2
Cluster EST : UnigeneHs.592177 [ NCBI ]
CGAP (NCI)Hs.592177
Alternative Splicing GalleryENSG00000105996
Gene ExpressionHOXA2 [ NCBI-GEO ]   HOXA2 [ EBI - ARRAY_EXPRESS ]   HOXA2 [ SEEK ]   HOXA2 [ MEM ]
Gene Expression Viewer (FireBrowse)HOXA2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3199
GTEX Portal (Tissue expression)HOXA2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43364   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43364  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43364
Splice isoforms : SwissVarO43364
PhosPhoSitePlusO43364
Domaine pattern : Prosite (Expaxy)ANTENNAPEDIA (PS00032)    HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_Antennapedia_CS    Homeobox_CS    Homeobox_dom    Homeobox_metazoa   
Domain families : Pfam (Sanger)Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)HOXA2
DMDM Disease mutations3199
Blocks (Seattle)HOXA2
SuperfamilyO43364
Human Protein AtlasENSG00000105996
Peptide AtlasO43364
HPRD05252
IPIIPI00012049   
Protein Interaction databases
DIP (DOE-UCLA)O43364
IntAct (EBI)O43364
FunCoupENSG00000105996
BioGRIDHOXA2
STRING (EMBL)HOXA2
ZODIACHOXA2
Ontologies - Pathways
QuickGOO43364
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  cell fate determination  osteoblast development  nucleus  transcription, DNA-templated  segment specification  motor neuron axon guidance  anterior/posterior pattern specification  dorsal/ventral pattern formation  rhombomere 2 development  rhombomere 3 morphogenesis  brain segmentation  middle ear morphogenesis  intracellular membrane-bounded organelle  negative regulation of neuron differentiation  negative regulation of osteoblast differentiation  positive regulation of transcription from RNA polymerase II promoter  embryonic viscerocranium morphogenesis  cellular response to retinoic acid  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding  cell fate determination  osteoblast development  nucleus  transcription, DNA-templated  segment specification  motor neuron axon guidance  anterior/posterior pattern specification  dorsal/ventral pattern formation  rhombomere 2 development  rhombomere 3 morphogenesis  brain segmentation  middle ear morphogenesis  intracellular membrane-bounded organelle  negative regulation of neuron differentiation  negative regulation of osteoblast differentiation  positive regulation of transcription from RNA polymerase II promoter  embryonic viscerocranium morphogenesis  cellular response to retinoic acid  
NDEx NetworkHOXA2
Atlas of Cancer Signalling NetworkHOXA2
Wikipedia pathwaysHOXA2
Orthology - Evolution
OrthoDB3199
GeneTree (enSembl)ENSG00000105996
Phylogenetic Trees/Animal Genes : TreeFamHOXA2
HOVERGENO43364
HOGENOMO43364
Homologs : HomoloGeneHOXA2
Homology/Alignments : Family Browser (UCSC)HOXA2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHOXA2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HOXA2
dbVarHOXA2
ClinVarHOXA2
1000_GenomesHOXA2 
Exome Variant ServerHOXA2
ExAC (Exome Aggregation Consortium)HOXA2 (select the gene name)
Genetic variants : HAPMAP3199
Genomic Variants (DGV)HOXA2 [DGVbeta]
DECIPHERHOXA2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHOXA2 
Mutations
ICGC Data PortalHOXA2 
TCGA Data PortalHOXA2 
Broad Tumor PortalHOXA2
OASIS PortalHOXA2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHOXA2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHOXA2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
BioMutasearch HOXA2
DgiDB (Drug Gene Interaction Database)HOXA2
DoCM (Curated mutations)HOXA2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HOXA2 (select a term)
intoGenHOXA2
Cancer3DHOXA2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604685    612290   
Orphanet17010    11575   
MedgenHOXA2
Genetic Testing Registry HOXA2
NextProtO43364 [Medical]
TSGene3199
GENETestsHOXA2
Target ValidationHOXA2
Huge Navigator HOXA2 [HugePedia]
snp3D : Map Gene to Disease3199
BioCentury BCIQHOXA2
ClinGenHOXA2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3199
Chemical/Pharm GKB GenePA29380
Clinical trialHOXA2
Miscellaneous
canSAR (ICR)HOXA2 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHOXA2
EVEXHOXA2
GoPubMedHOXA2
iHOPHOXA2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:10:41 CEST 2017

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