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HOXA3 (homeobox A3)

Identity

Alias (NCBI)HOX1
HOX1E
HGNC (Hugo) HOXA3
HGNC Previous nameHOX1E
 HOX1
HGNC Previous namehomeo box A3
LocusID (NCBI) 3200
Atlas_Id 56189
Location 7p15.2  [Link to chromosome band 7p15]
Location_base_pair Starts at 27106190 and ends at 27127020 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HOXA3 (7p15.2) / KIAA0895 (7p14.2)YY1AP1 (1q22) / HOXA3 (7p15.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)HOXA3   5104
Cards
Entrez_Gene (NCBI)HOXA3    homeobox A3
AliasesHOX1; HOX1E
GeneCards (Weizmann)HOXA3
Ensembl hg19 (Hinxton)ENSG00000105997 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105997 [Gene_View]  ENSG00000105997 [Sequence]  chr7:27106190-27127020 [Contig_View]  HOXA3 [Vega]
ICGC DataPortalENSG00000105997
TCGA cBioPortalHOXA3
AceView (NCBI)HOXA3
Genatlas (Paris)HOXA3
SOURCE (Princeton)HOXA3
Genetics Home Reference (NIH)HOXA3
Genomic and cartography
GoldenPath hg38 (UCSC)HOXA3  -     chr7:27106190-27127020 -  7p15.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HOXA3  -     7p15.2   [Description]    (hg19-Feb_2009)
GoldenPathHOXA3 - 7p15.2 [CytoView hg19]  HOXA3 - 7p15.2 [CytoView hg38]
ImmunoBaseENSG00000105997
Genome Data Viewer NCBIHOXA3 [Mapview hg19]  
OMIM142954   
Gene and transcription
Genbank (Entrez)AK056567 AK094200 BC015180 BM984673 DQ655986
RefSeq transcript (Entrez)NM_001384335 NM_001384336 NM_001384337 NM_001384338 NM_001384339 NM_001384340 NM_001384341 NM_001384342 NM_001384343 NM_001384344 NM_001384345 NM_001384346 NM_030661 NM_153631 NM_153632
Consensus coding sequences : CCDS (NCBI)HOXA3
Gene ExpressionHOXA3 [ NCBI-GEO ]   HOXA3 [ EBI - ARRAY_EXPRESS ]   HOXA3 [ SEEK ]   HOXA3 [ MEM ]
Gene Expression Viewer (FireBrowse)HOXA3 [ Firebrowse - Broad ]
GenevisibleExpression of HOXA3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3200
GTEX Portal (Tissue expression)HOXA3
Human Protein AtlasENSG00000105997-HOXA3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43365   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43365  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43365
PhosPhoSitePlusO43365
Domaine pattern : Prosite (Expaxy)ANTENNAPEDIA (PS00032)    HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)DUF4074    Homeobox-like_sf    Homeobox_Antennapedia_CS    Homeobox_CS    Homeobox_dom    Homeobox_metazoa   
Domain families : Pfam (Sanger)DUF4074 (PF13293)    Homeodomain (PF00046)   
Domain families : Pfam (NCBI)pfam13293    pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)HOXA3
SuperfamilyO43365
AlphaFold pdb e-kbO43365   
Human Protein Atlas [tissue]ENSG00000105997-HOXA3 [tissue]
HPRD00842
Protein Interaction databases
DIP (DOE-UCLA)O43365
IntAct (EBI)O43365
BioGRIDHOXA3
STRING (EMBL)HOXA3
ZODIACHOXA3
Ontologies - Pathways
QuickGOO43365
Ontology : AmiGOchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  angiogenesis  blood vessel remodeling  protein binding  nucleus  nucleoplasm  regulation of transcription by RNA polymerase II  positive regulation of cell population proliferation  anterior/posterior pattern specification  specification of animal organ position  gene expression  glossopharyngeal nerve morphogenesis  thyroid gland development  thymus development  animal organ formation  embryonic skeletal system morphogenesis  cartilage development  parathyroid gland development  HMG box domain binding  
Ontology : EGO-EBIchromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  angiogenesis  blood vessel remodeling  protein binding  nucleus  nucleoplasm  regulation of transcription by RNA polymerase II  positive regulation of cell population proliferation  anterior/posterior pattern specification  specification of animal organ position  gene expression  glossopharyngeal nerve morphogenesis  thyroid gland development  thymus development  animal organ formation  embryonic skeletal system morphogenesis  cartilage development  parathyroid gland development  HMG box domain binding  
NDEx NetworkHOXA3
Atlas of Cancer Signalling NetworkHOXA3
Wikipedia pathwaysHOXA3
Orthology - Evolution
OrthoDB3200
GeneTree (enSembl)ENSG00000105997
Phylogenetic Trees/Animal Genes : TreeFamHOXA3
Homologs : HomoloGeneHOXA3
Homology/Alignments : Family Browser (UCSC)HOXA3
Gene fusions - Rearrangements
Fusion : QuiverHOXA3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHOXA3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HOXA3
dbVarHOXA3
ClinVarHOXA3
MonarchHOXA3
1000_GenomesHOXA3 
Exome Variant ServerHOXA3
GNOMAD BrowserENSG00000105997
Varsome BrowserHOXA3
ACMGHOXA3 variants
VarityO43365
Genomic Variants (DGV)HOXA3 [DGVbeta]
DECIPHERHOXA3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHOXA3 
Mutations
ICGC Data PortalHOXA3 
TCGA Data PortalHOXA3 
Broad Tumor PortalHOXA3
OASIS PortalHOXA3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHOXA3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DHOXA3
Mutations and Diseases : HGMDHOXA3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaHOXA3
DgiDB (Drug Gene Interaction Database)HOXA3
DoCM (Curated mutations)HOXA3
CIViC (Clinical Interpretations of Variants in Cancer)HOXA3
Cancer3DHOXA3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM142954   
Orphanet
DisGeNETHOXA3
MedgenHOXA3
Genetic Testing Registry HOXA3
NextProtO43365 [Medical]
GENETestsHOXA3
Target ValidationHOXA3
Huge Navigator HOXA3 [HugePedia]
ClinGenHOXA3
Clinical trials, drugs, therapy
MyCancerGenomeHOXA3
Protein Interactions : CTDHOXA3
Pharm GKB GenePA29381
PharosO43365
Clinical trialHOXA3
Miscellaneous
canSAR (ICR)HOXA3
HarmonizomeHOXA3
DataMed IndexHOXA3
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXHOXA3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:12:46 CEST 2021

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