Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HOXA5 (homeobox A5)

Identity

Alias_namesHOX1C
HOX1
homeo box A5
Other aliasHOX1.3
HGNC (Hugo) HOXA5
LocusID (NCBI) 3202
Atlas_Id 40849
Location 7p15.2  [Link to chromosome band 7p15]
Location_base_pair Starts at 27141052 and ends at 27143668 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  Mediastinal Gray Zone Lymphoma
inv(7)(p15q34) TRB/HOXA10::t(7;7)(p15;q34) TRB/HOXA10


External links

Nomenclature
HGNC (Hugo)HOXA5   5106
Cards
Entrez_Gene (NCBI)HOXA5  3202  homeobox A5
AliasesHOX1; HOX1.3; HOX1C
GeneCards (Weizmann)HOXA5
Ensembl hg19 (Hinxton)ENSG00000106004 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106004 [Gene_View]  chr7:27141052-27143668 [Contig_View]  HOXA5 [Vega]
ICGC DataPortalENSG00000106004
TCGA cBioPortalHOXA5
AceView (NCBI)HOXA5
Genatlas (Paris)HOXA5
WikiGenes3202
SOURCE (Princeton)HOXA5
Genetics Home Reference (NIH)HOXA5
Genomic and cartography
GoldenPath hg38 (UCSC)HOXA5  -     chr7:27141052-27143668 -  7p15.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HOXA5  -     7p15.2   [Description]    (hg19-Feb_2009)
EnsemblHOXA5 - 7p15.2 [CytoView hg19]  HOXA5 - 7p15.2 [CytoView hg38]
Mapping of homologs : NCBIHOXA5 [Mapview hg19]  HOXA5 [Mapview hg38]
OMIM142952   
Gene and transcription
Genbank (Entrez)AW802886 BC013682 BI822268 BT009744 CR542256
RefSeq transcript (Entrez)NM_019102
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HOXA5
Cluster EST : UnigeneHs.655218 [ NCBI ]
CGAP (NCI)Hs.655218
Alternative Splicing GalleryENSG00000106004
Gene ExpressionHOXA5 [ NCBI-GEO ]   HOXA5 [ EBI - ARRAY_EXPRESS ]   HOXA5 [ SEEK ]   HOXA5 [ MEM ]
Gene Expression Viewer (FireBrowse)HOXA5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3202
GTEX Portal (Tissue expression)HOXA5
Protein : pattern, domain, 3D structure
UniProt/SwissProtP20719   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP20719  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP20719
Splice isoforms : SwissVarP20719
PhosPhoSitePlusP20719
Domaine pattern : Prosite (Expaxy)ANTENNAPEDIA (PS00032)    HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_antennapedia    Homeobox_Antennapedia_CS    Homeobox_CS    Homeobox_dom    Homeobox_metazoa   
Domain families : Pfam (Sanger)Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)HOXA5
DMDM Disease mutations3202
Blocks (Seattle)HOXA5
SuperfamilyP20719
Human Protein AtlasENSG00000106004
Peptide AtlasP20719
HPRD00840
IPIIPI00302291   IPI00977858   
Protein Interaction databases
DIP (DOE-UCLA)P20719
IntAct (EBI)P20719
FunCoupENSG00000106004
BioGRIDHOXA5
STRING (EMBL)HOXA5
ZODIACHOXA5
Ontologies - Pathways
QuickGOP20719
Ontology : AmiGORNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  respiratory system process  DNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  transcription from RNA polymerase II promoter  anterior/posterior pattern specification  positive regulation of receptor biosynthetic process  cell migration  negative regulation of angiogenesis  thyroid gland development  regulation of mammary gland epithelial cell proliferation  multicellular organism growth  positive regulation of apoptotic process  positive regulation of myeloid cell differentiation  negative regulation of erythrocyte differentiation  positive regulation of transcription from RNA polymerase II promoter  lung alveolus development  embryonic skeletal system morphogenesis  bronchiole development  epithelial tube branching involved in lung morphogenesis  lung goblet cell differentiation  lung-associated mesenchyme development  trachea cartilage morphogenesis  intestinal epithelial cell maturation  mesenchymal-epithelial cell signaling  mammary gland epithelial cell differentiation  mammary gland alveolus development  cell-cell signaling involved in mammary gland development  
Ontology : EGO-EBIRNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  respiratory system process  DNA binding  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  transcription from RNA polymerase II promoter  anterior/posterior pattern specification  positive regulation of receptor biosynthetic process  cell migration  negative regulation of angiogenesis  thyroid gland development  regulation of mammary gland epithelial cell proliferation  multicellular organism growth  positive regulation of apoptotic process  positive regulation of myeloid cell differentiation  negative regulation of erythrocyte differentiation  positive regulation of transcription from RNA polymerase II promoter  lung alveolus development  embryonic skeletal system morphogenesis  bronchiole development  epithelial tube branching involved in lung morphogenesis  lung goblet cell differentiation  lung-associated mesenchyme development  trachea cartilage morphogenesis  intestinal epithelial cell maturation  mesenchymal-epithelial cell signaling  mammary gland epithelial cell differentiation  mammary gland alveolus development  cell-cell signaling involved in mammary gland development  
NDEx NetworkHOXA5
Atlas of Cancer Signalling NetworkHOXA5
Wikipedia pathwaysHOXA5
Orthology - Evolution
OrthoDB3202
GeneTree (enSembl)ENSG00000106004
Phylogenetic Trees/Animal Genes : TreeFamHOXA5
HOVERGENP20719
HOGENOMP20719
Homologs : HomoloGeneHOXA5
Homology/Alignments : Family Browser (UCSC)HOXA5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHOXA5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HOXA5
dbVarHOXA5
ClinVarHOXA5
1000_GenomesHOXA5 
Exome Variant ServerHOXA5
ExAC (Exome Aggregation Consortium)HOXA5 (select the gene name)
Genetic variants : HAPMAP3202
Genomic Variants (DGV)HOXA5 [DGVbeta]
DECIPHERHOXA5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHOXA5 
Mutations
ICGC Data PortalHOXA5 
TCGA Data PortalHOXA5 
Broad Tumor PortalHOXA5
OASIS PortalHOXA5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHOXA5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHOXA5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HOXA5
DgiDB (Drug Gene Interaction Database)HOXA5
DoCM (Curated mutations)HOXA5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HOXA5 (select a term)
intoGenHOXA5
Cancer3DHOXA5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM142952   
Orphanet
MedgenHOXA5
Genetic Testing Registry HOXA5
NextProtP20719 [Medical]
TSGene3202
GENETestsHOXA5
Huge Navigator HOXA5 [HugePedia]
snp3D : Map Gene to Disease3202
BioCentury BCIQHOXA5
ClinGenHOXA5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3202
Chemical/Pharm GKB GenePA29383
Clinical trialHOXA5
Miscellaneous
canSAR (ICR)HOXA5 (select the gene name)
Probes
Litterature
PubMed60 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHOXA5
EVEXHOXA5
GoPubMedHOXA5
iHOPHOXA5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:19:17 CEST 2017

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