Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HOXA7 (homeobox A7)

Identity

Alias_namesHOX1A
HOX1
homeo box A7
Other aliasANTP
HOX1.1
HGNC (Hugo) HOXA7
LocusID (NCBI) 3204
Atlas_Id 40850
Location 7p15.2  [Link to chromosome band 7p15]
Location_base_pair Starts at 27153719 and ends at 27156677 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 4 ]
  inv(7)(p15q34) TRB/HOXA10::t(7;7)(p15;q34) TRB/HOXA10
t(7;14)(p15;q11) TRD/HOXA10
t(11;16)(q23;p13.3) KMT2A/CREBBP
t(11;19)(q23;p13) KMT2A/SH3GL1


External links

Nomenclature
HGNC (Hugo)HOXA7   5108
Cards
Entrez_Gene (NCBI)HOXA7  3204  homeobox A7
AliasesANTP; HOX1; HOX1.1; HOX1A
GeneCards (Weizmann)HOXA7
Ensembl hg19 (Hinxton)ENSG00000122592 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000122592 [Gene_View]  chr7:27153719-27156677 [Contig_View]  HOXA7 [Vega]
ICGC DataPortalENSG00000122592
TCGA cBioPortalHOXA7
AceView (NCBI)HOXA7
Genatlas (Paris)HOXA7
WikiGenes3204
SOURCE (Princeton)HOXA7
Genetics Home Reference (NIH)HOXA7
Genomic and cartography
GoldenPath hg38 (UCSC)HOXA7  -     chr7:27153719-27156677 -  7p15.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HOXA7  -     7p15.2   [Description]    (hg19-Feb_2009)
EnsemblHOXA7 - 7p15.2 [CytoView hg19]  HOXA7 - 7p15.2 [CytoView hg38]
Mapping of homologs : NCBIHOXA7 [Mapview hg19]  HOXA7 [Mapview hg38]
OMIM142950   
Gene and transcription
Genbank (Entrez)AF026397 AW793597 BC061916 BC140401 BC148692
RefSeq transcript (Entrez)NM_006896
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HOXA7
Cluster EST : UnigeneHs.660918 [ NCBI ]
CGAP (NCI)Hs.660918
Alternative Splicing GalleryENSG00000122592
Gene ExpressionHOXA7 [ NCBI-GEO ]   HOXA7 [ EBI - ARRAY_EXPRESS ]   HOXA7 [ SEEK ]   HOXA7 [ MEM ]
Gene Expression Viewer (FireBrowse)HOXA7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3204
GTEX Portal (Tissue expression)HOXA7
Protein : pattern, domain, 3D structure
UniProt/SwissProtP31268   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP31268  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP31268
Splice isoforms : SwissVarP31268
PhosPhoSitePlusP31268
Domaine pattern : Prosite (Expaxy)ANTENNAPEDIA (PS00032)    HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_antennapedia    Homeobox_Antennapedia_CS    Homeobox_CS    Homeobox_dom    Homeobox_metazoa   
Domain families : Pfam (Sanger)Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)HOXA7
DMDM Disease mutations3204
Blocks (Seattle)HOXA7
SuperfamilyP31268
Human Protein AtlasENSG00000122592
Peptide AtlasP31268
HPRD00838
IPIIPI00010743   IPI00980848   
Protein Interaction databases
DIP (DOE-UCLA)P31268
IntAct (EBI)P31268
FunCoupENSG00000122592
BioGRIDHOXA7
STRING (EMBL)HOXA7
ZODIACHOXA7
Ontologies - Pathways
QuickGOP31268
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  angiogenesis  negative regulation of cell-matrix adhesion  negative regulation of leukocyte migration  nucleus  nucleoplasm  transcription from RNA polymerase II promoter  transcription factor binding  anterior/posterior pattern specification  nuclear membrane  sequence-specific DNA binding  negative regulation of keratinocyte differentiation  negative regulation of monocyte differentiation  negative regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  embryonic skeletal system morphogenesis  stem cell differentiation  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  angiogenesis  negative regulation of cell-matrix adhesion  negative regulation of leukocyte migration  nucleus  nucleoplasm  transcription from RNA polymerase II promoter  transcription factor binding  anterior/posterior pattern specification  nuclear membrane  sequence-specific DNA binding  negative regulation of keratinocyte differentiation  negative regulation of monocyte differentiation  negative regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  embryonic skeletal system morphogenesis  stem cell differentiation  
Pathways : BIOCARTAKeratinocyte Differentiation [Genes]   
NDEx NetworkHOXA7
Atlas of Cancer Signalling NetworkHOXA7
Wikipedia pathwaysHOXA7
Orthology - Evolution
OrthoDB3204
GeneTree (enSembl)ENSG00000122592
Phylogenetic Trees/Animal Genes : TreeFamHOXA7
HOVERGENP31268
HOGENOMP31268
Homologs : HomoloGeneHOXA7
Homology/Alignments : Family Browser (UCSC)HOXA7
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHOXA7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HOXA7
dbVarHOXA7
ClinVarHOXA7
1000_GenomesHOXA7 
Exome Variant ServerHOXA7
ExAC (Exome Aggregation Consortium)HOXA7 (select the gene name)
Genetic variants : HAPMAP3204
Genomic Variants (DGV)HOXA7 [DGVbeta]
DECIPHERHOXA7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHOXA7 
Mutations
ICGC Data PortalHOXA7 
TCGA Data PortalHOXA7 
Broad Tumor PortalHOXA7
OASIS PortalHOXA7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHOXA7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHOXA7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HOXA7
DgiDB (Drug Gene Interaction Database)HOXA7
DoCM (Curated mutations)HOXA7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HOXA7 (select a term)
intoGenHOXA7
Cancer3DHOXA7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM142950   
Orphanet
MedgenHOXA7
Genetic Testing Registry HOXA7
NextProtP31268 [Medical]
TSGene3204
GENETestsHOXA7
Target ValidationHOXA7
Huge Navigator HOXA7 [HugePedia]
snp3D : Map Gene to Disease3204
BioCentury BCIQHOXA7
ClinGenHOXA7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3204
Chemical/Pharm GKB GenePA29385
Clinical trialHOXA7
Miscellaneous
canSAR (ICR)HOXA7 (select the gene name)
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHOXA7
EVEXHOXA7
GoPubMedHOXA7
iHOPHOXA7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:37:18 CEST 2017

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