Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HOXB1 (homeobox B1)

Identity

Alias_namesHOX2
HOX2I
homeo box B1
Other aliasHCFP3
Hox-2.9
HGNC (Hugo) HOXB1
LocusID (NCBI) 3211
Atlas_Id 55862
Location 17q21.32  [Link to chromosome band 17q21]
Location_base_pair Starts at 48529445 and ends at 48530910 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HOXB1   5111
Cards
Entrez_Gene (NCBI)HOXB1  3211  homeobox B1
AliasesHCFP3; HOX2; HOX2I; Hox-2.9
GeneCards (Weizmann)HOXB1
Ensembl hg19 (Hinxton)ENSG00000120094 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000120094 [Gene_View]  chr17:48529445-48530910 [Contig_View]  HOXB1 [Vega]
ICGC DataPortalENSG00000120094
TCGA cBioPortalHOXB1
AceView (NCBI)HOXB1
Genatlas (Paris)HOXB1
WikiGenes3211
SOURCE (Princeton)HOXB1
Genetics Home Reference (NIH)HOXB1
Genomic and cartography
GoldenPath hg38 (UCSC)HOXB1  -     chr17:48529445-48530910 -  17q21.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HOXB1  -     17q21.32   [Description]    (hg19-Feb_2009)
EnsemblHOXB1 - 17q21.32 [CytoView hg19]  HOXB1 - 17q21.32 [CytoView hg38]
Mapping of homologs : NCBIHOXB1 [Mapview hg19]  HOXB1 [Mapview hg38]
OMIM142968   614744   
Gene and transcription
Genbank (Entrez)BC096191 BC096192 BC096193 BC099633 X16666
RefSeq transcript (Entrez)NM_002144
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HOXB1
Cluster EST : UnigeneHs.99992 [ NCBI ]
CGAP (NCI)Hs.99992
Alternative Splicing GalleryENSG00000120094
Gene ExpressionHOXB1 [ NCBI-GEO ]   HOXB1 [ EBI - ARRAY_EXPRESS ]   HOXB1 [ SEEK ]   HOXB1 [ MEM ]
Gene Expression Viewer (FireBrowse)HOXB1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3211
GTEX Portal (Tissue expression)HOXB1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP14653   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP14653  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP14653
Splice isoforms : SwissVarP14653
PhosPhoSitePlusP14653
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_CS    Homeobox_dom    Homeobox_metazoa   
Domain families : Pfam (Sanger)Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)HOXB1
DMDM Disease mutations3211
Blocks (Seattle)HOXB1
PDB (SRS)1B72   
PDB (PDBSum)1B72   
PDB (IMB)1B72   
PDB (RSDB)1B72   
Structural Biology KnowledgeBase1B72   
SCOP (Structural Classification of Proteins)1B72   
CATH (Classification of proteins structures)1B72   
SuperfamilyP14653
Human Protein AtlasENSG00000120094
Peptide AtlasP14653
HPRD00855
IPIIPI00294724   IPI00607572   
Protein Interaction databases
DIP (DOE-UCLA)P14653
IntAct (EBI)P14653
FunCoupENSG00000120094
BioGRIDHOXB1
STRING (EMBL)HOXB1
ZODIACHOXB1
Ontologies - Pathways
QuickGOP14653
Ontology : AmiGORNA polymerase II regulatory region sequence-specific DNA binding  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding  DNA binding  nucleus  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  multicellular organism development  pattern specification process  anterior/posterior pattern specification  protein domain specific binding  rhombomere 4 development  rhombomere 5 development  facial nerve structural organization  facial nucleus development  positive regulation of transcription from RNA polymerase II promoter  anatomical structure formation involved in morphogenesis  embryonic skeletal system morphogenesis  
Ontology : EGO-EBIRNA polymerase II regulatory region sequence-specific DNA binding  RNA polymerase II core promoter proximal region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding  DNA binding  nucleus  regulation of transcription, DNA-templated  transcription from RNA polymerase II promoter  multicellular organism development  pattern specification process  anterior/posterior pattern specification  protein domain specific binding  rhombomere 4 development  rhombomere 5 development  facial nerve structural organization  facial nucleus development  positive regulation of transcription from RNA polymerase II promoter  anatomical structure formation involved in morphogenesis  embryonic skeletal system morphogenesis  
NDEx NetworkHOXB1
Atlas of Cancer Signalling NetworkHOXB1
Wikipedia pathwaysHOXB1
Orthology - Evolution
OrthoDB3211
GeneTree (enSembl)ENSG00000120094
Phylogenetic Trees/Animal Genes : TreeFamHOXB1
HOVERGENP14653
HOGENOMP14653
Homologs : HomoloGeneHOXB1
Homology/Alignments : Family Browser (UCSC)HOXB1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHOXB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HOXB1
dbVarHOXB1
ClinVarHOXB1
1000_GenomesHOXB1 
Exome Variant ServerHOXB1
ExAC (Exome Aggregation Consortium)HOXB1 (select the gene name)
Genetic variants : HAPMAP3211
Genomic Variants (DGV)HOXB1 [DGVbeta]
DECIPHERHOXB1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHOXB1 
Mutations
ICGC Data PortalHOXB1 
TCGA Data PortalHOXB1 
Broad Tumor PortalHOXB1
OASIS PortalHOXB1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHOXB1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHOXB1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HOXB1
DgiDB (Drug Gene Interaction Database)HOXB1
DoCM (Curated mutations)HOXB1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HOXB1 (select a term)
intoGenHOXB1
Cancer3DHOXB1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM142968    614744   
Orphanet21226   
MedgenHOXB1
Genetic Testing Registry HOXB1
NextProtP14653 [Medical]
TSGene3211
GENETestsHOXB1
Target ValidationHOXB1
Huge Navigator HOXB1 [HugePedia]
snp3D : Map Gene to Disease3211
BioCentury BCIQHOXB1
ClinGenHOXB1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3211
Chemical/Pharm GKB GenePA29387
Clinical trialHOXB1
Miscellaneous
canSAR (ICR)HOXB1 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHOXB1
EVEXHOXB1
GoPubMedHOXB1
iHOPHOXB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 17:03:17 CEST 2017

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