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HOXB13 (homeobox B13)

Identity

Alias (NCBI)HPC9
PSGD
HGNC (Hugo) HOXB13
HGNC Previous namehomeo box B13
LocusID (NCBI) 10481
Atlas_Id 46597
Location 17q21.32  [Link to chromosome band 17q21]
Location_base_pair Starts at 48724765 and ends at 48728750 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HOXB13 (17q21.32) / ACTG2 (2p13.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)HOXB13   5112
LRG (Locus Reference Genomic)LRG_771
Cards
Entrez_Gene (NCBI)HOXB13    homeobox B13
AliasesHPC9; PSGD
GeneCards (Weizmann)HOXB13
Ensembl hg19 (Hinxton)ENSG00000159184 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000159184 [Gene_View]  ENSG00000159184 [Sequence]  chr17:48724765-48728750 [Contig_View]  HOXB13 [Vega]
ICGC DataPortalENSG00000159184
TCGA cBioPortalHOXB13
AceView (NCBI)HOXB13
Genatlas (Paris)HOXB13
SOURCE (Princeton)HOXB13
Genetics Home Reference (NIH)HOXB13
Genomic and cartography
GoldenPath hg38 (UCSC)HOXB13  -     chr17:48724765-48728750 -  17q21.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HOXB13  -     17q21.32   [Description]    (hg19-Feb_2009)
GoldenPathHOXB13 - 17q21.32 [CytoView hg19]  HOXB13 - 17q21.32 [CytoView hg38]
ImmunoBaseENSG00000159184
Genome Data Viewer NCBIHOXB13 [Mapview hg19]  
OMIM604607   610997   
Gene and transcription
Genbank (Entrez)AK225234 AK313266 AY937237 BC007092 BC070233
RefSeq transcript (Entrez)NM_006361
Consensus coding sequences : CCDS (NCBI)HOXB13
Gene ExpressionHOXB13 [ NCBI-GEO ]   HOXB13 [ EBI - ARRAY_EXPRESS ]   HOXB13 [ SEEK ]   HOXB13 [ MEM ]
Gene Expression Viewer (FireBrowse)HOXB13 [ Firebrowse - Broad ]
GenevisibleExpression of HOXB13 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10481
GTEX Portal (Tissue expression)HOXB13
Human Protein AtlasENSG00000159184-HOXB13 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ92826   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ92826  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ92826
PhosPhoSitePlusQ92826
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like_sf    Homeobox_CS    Homeobox_dom    HoxA13_N   
Domain families : Pfam (Sanger)Homeodomain (PF00046)    HoxA13_N (PF12284)   
Domain families : Pfam (NCBI)pfam00046    pfam12284   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)HOXB13
PDB (RSDB)2CRA    5EDN    5EEA    5EF6    5EG0    5EGO    5NO6   
PDB Europe2CRA    5EDN    5EEA    5EF6    5EG0    5EGO    5NO6   
PDB (PDBSum)2CRA    5EDN    5EEA    5EF6    5EG0    5EGO    5NO6   
PDB (IMB)2CRA    5EDN    5EEA    5EF6    5EG0    5EGO    5NO6   
Structural Biology KnowledgeBase2CRA    5EDN    5EEA    5EF6    5EG0    5EGO    5NO6   
SCOP (Structural Classification of Proteins)2CRA    5EDN    5EEA    5EF6    5EG0    5EGO    5NO6   
CATH (Classification of proteins structures)2CRA    5EDN    5EEA    5EF6    5EG0    5EGO    5NO6   
SuperfamilyQ92826
AlphaFold pdb e-kbQ92826   
Human Protein Atlas [tissue]ENSG00000159184-HOXB13 [tissue]
HPRD05210
Protein Interaction databases
DIP (DOE-UCLA)Q92826
IntAct (EBI)Q92826
BioGRIDHOXB13
STRING (EMBL)HOXB13
ZODIACHOXB13
Ontologies - Pathways
QuickGOQ92826
Ontology : AmiGOnegative regulation of transcription by RNA polymerase II  chromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  angiogenesis  protein binding  nucleoplasm  transcription regulator complex  regulation of transcription by RNA polymerase II  methyl-CpG binding  epidermis development  response to wounding  response to testosterone  regulation of growth  sequence-specific DNA binding  prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis  epithelial cell maturation involved in prostate gland development  sequence-specific double-stranded DNA binding  
Ontology : EGO-EBInegative regulation of transcription by RNA polymerase II  chromatin  RNA polymerase II cis-regulatory region sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription repressor activity, RNA polymerase II-specific  angiogenesis  protein binding  nucleoplasm  transcription regulator complex  regulation of transcription by RNA polymerase II  methyl-CpG binding  epidermis development  response to wounding  response to testosterone  regulation of growth  sequence-specific DNA binding  prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis  epithelial cell maturation involved in prostate gland development  sequence-specific double-stranded DNA binding  
NDEx NetworkHOXB13
Atlas of Cancer Signalling NetworkHOXB13
Wikipedia pathwaysHOXB13
Orthology - Evolution
OrthoDB10481
GeneTree (enSembl)ENSG00000159184
Phylogenetic Trees/Animal Genes : TreeFamHOXB13
Homologs : HomoloGeneHOXB13
Homology/Alignments : Family Browser (UCSC)HOXB13
Gene fusions - Rearrangements
Fusion : QuiverHOXB13
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHOXB13 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HOXB13
dbVarHOXB13
ClinVarHOXB13
MonarchHOXB13
1000_GenomesHOXB13 
Exome Variant ServerHOXB13
GNOMAD BrowserENSG00000159184
Varsome BrowserHOXB13
ACMGHOXB13 variants
VarityQ92826
Genomic Variants (DGV)HOXB13 [DGVbeta]
DECIPHERHOXB13 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHOXB13 
Mutations
ICGC Data PortalHOXB13 
TCGA Data PortalHOXB13 
Broad Tumor PortalHOXB13
OASIS PortalHOXB13 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHOXB13  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DHOXB13
Mutations and Diseases : HGMDHOXB13
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaHOXB13
DgiDB (Drug Gene Interaction Database)HOXB13
DoCM (Curated mutations)HOXB13
CIViC (Clinical Interpretations of Variants in Cancer)HOXB13
Cancer3DHOXB13
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604607    610997   
Orphanet903   
DisGeNETHOXB13
MedgenHOXB13
Genetic Testing Registry HOXB13
NextProtQ92826 [Medical]
GENETestsHOXB13
Target ValidationHOXB13
Huge Navigator HOXB13 [HugePedia]
ClinGenHOXB13
Clinical trials, drugs, therapy
MyCancerGenomeHOXB13
Protein Interactions : CTDHOXB13
Pharm GKB GenePA29388
PharosQ92826
Clinical trialHOXB13
Miscellaneous
canSAR (ICR)HOXB13
HarmonizomeHOXB13
DataMed IndexHOXB13
Probes
Litterature
PubMed125 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXHOXB13
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:12:48 CEST 2021

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