| Nomenclature |
|---|
| HGNC (Hugo) | HOXB2 5113 |
| Cards |
|---|
| Entrez_Gene (NCBI) | HOXB2 3212 homeobox B2 |
| Aliases | HOX2; HOX2H; Hox-2.8; K8 |
| GeneCards (Weizmann) | HOXB2 |
| Ensembl hg19 (Hinxton) | ENSG00000173917 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000173917 [Gene_View] ENSG00000173917 [Sequence] chr17:48542656-48545031 [Contig_View] HOXB2 [Vega] |
| ICGC DataPortal | ENSG00000173917 |
| TCGA cBioPortal | HOXB2 |
| AceView (NCBI) | HOXB2 |
| Genatlas (Paris) | HOXB2 |
| WikiGenes | 3212 |
| SOURCE (Princeton) | HOXB2 |
| Genetics Home Reference (NIH) | HOXB2 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | HOXB2 - chr17:48542656-48545031 - 17q21.32 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | HOXB2 - 17q21.32 [Description] (hg19-Feb_2009) |
| Ensembl | HOXB2 - 17q21.32 [CytoView hg19] HOXB2 - 17q21.32 [CytoView hg38] |
| Mapping of homologs : NCBI | HOXB2 [Mapview hg19] HOXB2 [Mapview hg38] |
| OMIM | 142967 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AA450237 BC038968 BC074805 BC074806 M73999 |
| RefSeq transcript (Entrez) | NM_002145 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | HOXB2 |
| Cluster EST : Unigene | Hs.514289 [ NCBI ] |
| CGAP (NCI) | Hs.514289 |
| Alternative Splicing Gallery | ENSG00000173917 |
| Gene Expression | HOXB2 [ NCBI-GEO ] HOXB2 [ EBI - ARRAY_EXPRESS ]
HOXB2 [ SEEK ] HOXB2 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | HOXB2 [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 3212 |
| GTEX Portal (Tissue expression) | HOXB2 |
| Human Protein Atlas | ENSG00000173917-HOXB2 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | P14652 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | P14652 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | P14652 |
| Splice isoforms : SwissVar | P14652 |
| PhosPhoSitePlus | P14652 |
| Domaine pattern : Prosite (Expaxy) | ANTENNAPEDIA (PS00032) HOMEOBOX_1 (PS00027) HOMEOBOX_2 (PS50071) |
| Domains : Interpro (EBI) | Homeobox-like_sf Homeobox_Antennapedia_CS Homeobox_CS Homeobox_dom Homeobox_metazoa |
| Domain families : Pfam (Sanger) | Homeobox (PF00046) |
| Domain families : Pfam (NCBI) | pfam00046 |
| Domain families : Smart (EMBL) | HOX (SM00389) |
| Conserved Domain (NCBI) | HOXB2 |
| DMDM Disease mutations | 3212 |
| Blocks (Seattle) | HOXB2 |
| Superfamily | P14652 |
| Human Protein Atlas [tissue] | ENSG00000173917-HOXB2 [tissue] |
| Peptide Atlas | P14652 |
| HPRD | 00854 |
| IPI | IPI00027261 IPI00383021 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | P14652 |
| IntAct (EBI) | P14652 |
| FunCoup | ENSG00000173917 |
| BioGRID | HOXB2 |
| STRING (EMBL) | HOXB2 |
| ZODIAC | HOXB2 |
| Ontologies - Pathways |
|---|
| QuickGO | P14652 |
| Ontology : AmiGO | RNA polymerase II proximal promoter sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding morphogenesis of an epithelial sheet DNA-binding transcription factor activity nucleus nucleus nucleoplasm cytosol transcription by RNA polymerase II multicellular organism development blood circulation anterior/posterior pattern specification dorsal/ventral pattern formation nuclear speck rhombomere 3 development rhombomere 4 development facial nerve structural organization sequence-specific DNA binding positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II embryonic skeletal system morphogenesis neural nucleus development |
| Ontology : EGO-EBI | RNA polymerase II proximal promoter sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding morphogenesis of an epithelial sheet DNA-binding transcription factor activity nucleus nucleus nucleoplasm cytosol transcription by RNA polymerase II multicellular organism development blood circulation anterior/posterior pattern specification dorsal/ventral pattern formation nuclear speck rhombomere 3 development rhombomere 4 development facial nerve structural organization sequence-specific DNA binding positive regulation of transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II embryonic skeletal system morphogenesis neural nucleus development |
| NDEx Network | HOXB2 |
| Atlas of Cancer Signalling Network | HOXB2 |
| Wikipedia pathways | HOXB2 |
| Orthology - Evolution |
|---|
| OrthoDB | 3212 |
| GeneTree (enSembl) | ENSG00000173917 |
| Phylogenetic Trees/Animal Genes : TreeFam | HOXB2 |
| HOVERGEN | P14652 |
| HOGENOM | P14652 |
| Homologs : HomoloGene | HOXB2 |
| Homology/Alignments : Family Browser (UCSC) | HOXB2 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | HOXB2 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | HOXB2 [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | HOXB2 |
| dbVar | HOXB2 |
| ClinVar | HOXB2 |
| 1000_Genomes | HOXB2 |
| Exome Variant Server | HOXB2 |
| ExAC (Exome Aggregation Consortium) | ENSG00000173917 |
| GNOMAD Browser | ENSG00000173917 |
| Varsome Browser | HOXB2 |
| Genetic variants : HAPMAP | 3212 |
| Genomic Variants (DGV) | HOXB2 [DGVbeta] |
| DECIPHER | HOXB2 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | HOXB2 |
| Mutations |
|---|
| ICGC Data Portal | HOXB2 |
| TCGA Data Portal | HOXB2 |
| Broad Tumor Portal | HOXB2 |
| OASIS Portal | HOXB2 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | HOXB2 [overview] [genome browser] [tissue] [distribution] |
| Mutations and Diseases : HGMD | HOXB2 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search HOXB2 |
| DgiDB (Drug Gene Interaction Database) | HOXB2 |
| DoCM (Curated mutations) | HOXB2 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | HOXB2 (select a term) |
| intoGen | HOXB2 |
| Cancer3D | HOXB2(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 142967 |
| Orphanet | |
| DisGeNET | HOXB2 |
| Medgen | HOXB2 |
| Genetic Testing Registry | HOXB2
|
| NextProt | P14652 [Medical] |
| TSGene | 3212 |
| GENETests | HOXB2 |
| Target Validation | HOXB2 |
| Huge Navigator |
HOXB2 [HugePedia] |
| snp3D : Map Gene to Disease | 3212 |
| BioCentury BCIQ | HOXB2 |
| ClinGen | HOXB2 |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 3212 |
| Chemical/Pharm GKB Gene | PA29389 |
| Clinical trial | HOXB2 |
| Miscellaneous |
|---|
| canSAR (ICR) | HOXB2 (select the gene name) |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 35 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | HOXB2 |
| EVEX | HOXB2 |
| GoPubMed | HOXB2 |
| iHOP | HOXB2 |
