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HOXB5 (homeobox B5)

Identity

Alias_namesHOX2
HOX2A
homeo box B5
Other aliasHHO.C10
HU-1
Hox2.1
HGNC (Hugo) HOXB5
LocusID (NCBI) 3215
Atlas_Id 49769
Location 17q21.32  [Link to chromosome band 17q21]
Location_base_pair Starts at 48591257 and ends at 48593741 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HOXB5   5116
Cards
Entrez_Gene (NCBI)HOXB5  3215  homeobox B5
AliasesHHO.C10; HOX2; HOX2A; HU-1; 
Hox2.1
GeneCards (Weizmann)HOXB5
Ensembl hg19 (Hinxton)ENSG00000120075 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000120075 [Gene_View]  chr17:48591257-48593741 [Contig_View]  HOXB5 [Vega]
ICGC DataPortalENSG00000120075
TCGA cBioPortalHOXB5
AceView (NCBI)HOXB5
Genatlas (Paris)HOXB5
WikiGenes3215
SOURCE (Princeton)HOXB5
Genetics Home Reference (NIH)HOXB5
Genomic and cartography
GoldenPath hg38 (UCSC)HOXB5  -     chr17:48591257-48593741 -  17q21.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HOXB5  -     17q21.32   [Description]    (hg19-Feb_2009)
EnsemblHOXB5 - 17q21.32 [CytoView hg19]  HOXB5 - 17q21.32 [CytoView hg38]
Mapping of homologs : NCBIHOXB5 [Mapview hg19]  HOXB5 [Mapview hg38]
OMIM142960   
Gene and transcription
Genbank (Entrez)AK314964 BC004454 BC008940 BC117247 BE621135
RefSeq transcript (Entrez)NM_002147
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HOXB5
Cluster EST : UnigeneHs.654456 [ NCBI ]
CGAP (NCI)Hs.654456
Alternative Splicing GalleryENSG00000120075
Gene ExpressionHOXB5 [ NCBI-GEO ]   HOXB5 [ EBI - ARRAY_EXPRESS ]   HOXB5 [ SEEK ]   HOXB5 [ MEM ]
Gene Expression Viewer (FireBrowse)HOXB5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3215
GTEX Portal (Tissue expression)HOXB5
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09067   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP09067  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP09067
Splice isoforms : SwissVarP09067
PhosPhoSitePlusP09067
Domaine pattern : Prosite (Expaxy)ANTENNAPEDIA (PS00032)    HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_antennapedia    Homeobox_Antennapedia_CS    Homeobox_CS    Homeobox_dom    Homeobox_metazoa   
Domain families : Pfam (Sanger)Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)HOXB5
DMDM Disease mutations3215
Blocks (Seattle)HOXB5
SuperfamilyP09067
Human Protein AtlasENSG00000120075
Peptide AtlasP09067
HPRD00848
IPIIPI00012514   
Protein Interaction databases
DIP (DOE-UCLA)P09067
IntAct (EBI)P09067
FunCoupENSG00000120075
BioGRIDHOXB5
STRING (EMBL)HOXB5
ZODIACHOXB5
Ontologies - Pathways
QuickGOP09067
Ontology : AmiGORNA polymerase II distal enhancer sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding  fibrillar center  protein binding  nucleus  cytosol  transcription from RNA polymerase II promoter  anatomical structure morphogenesis  anterior/posterior pattern specification  endothelial cell differentiation  positive regulation of transcription from RNA polymerase II promoter  embryonic skeletal system morphogenesis  
Ontology : EGO-EBIRNA polymerase II distal enhancer sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding  fibrillar center  protein binding  nucleus  cytosol  transcription from RNA polymerase II promoter  anatomical structure morphogenesis  anterior/posterior pattern specification  endothelial cell differentiation  positive regulation of transcription from RNA polymerase II promoter  embryonic skeletal system morphogenesis  
NDEx NetworkHOXB5
Atlas of Cancer Signalling NetworkHOXB5
Wikipedia pathwaysHOXB5
Orthology - Evolution
OrthoDB3215
GeneTree (enSembl)ENSG00000120075
Phylogenetic Trees/Animal Genes : TreeFamHOXB5
HOVERGENP09067
HOGENOMP09067
Homologs : HomoloGeneHOXB5
Homology/Alignments : Family Browser (UCSC)HOXB5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHOXB5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HOXB5
dbVarHOXB5
ClinVarHOXB5
1000_GenomesHOXB5 
Exome Variant ServerHOXB5
ExAC (Exome Aggregation Consortium)HOXB5 (select the gene name)
Genetic variants : HAPMAP3215
Genomic Variants (DGV)HOXB5 [DGVbeta]
DECIPHERHOXB5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHOXB5 
Mutations
ICGC Data PortalHOXB5 
TCGA Data PortalHOXB5 
Broad Tumor PortalHOXB5
OASIS PortalHOXB5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHOXB5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHOXB5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HOXB5
DgiDB (Drug Gene Interaction Database)HOXB5
DoCM (Curated mutations)HOXB5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HOXB5 (select a term)
intoGenHOXB5
Cancer3DHOXB5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM142960   
Orphanet
MedgenHOXB5
Genetic Testing Registry HOXB5
NextProtP09067 [Medical]
TSGene3215
GENETestsHOXB5
Target ValidationHOXB5
Huge Navigator HOXB5 [HugePedia]
snp3D : Map Gene to Disease3215
BioCentury BCIQHOXB5
ClinGenHOXB5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3215
Chemical/Pharm GKB GenePA29392
Clinical trialHOXB5
Miscellaneous
canSAR (ICR)HOXB5 (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHOXB5
EVEXHOXB5
GoPubMedHOXB5
iHOPHOXB5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:12:07 CEST 2017

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