HOXD1 (homeobox D1)

2010-11-01  

Identity

HGNC
LOCATION
2q31.1
LOCUSID
ALIAS
HOX4,HOX4G,Hox-4.7
FUSION GENES

Other Information

Locus ID:

NCBI: 3231
MIM: 142987
HGNC: 5132
Ensembl: ENSG00000128645

Variants:

dbSNP: 3231
ClinVar: 3231
TCGA: ENSG00000128645
COSMIC: HOXD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000128645ENST00000331462Q9GZZ0

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
Activation of HOX genes during differentiationREACTOMER-HSA-5619507
Activation of anterior HOX genes in hindbrain development during early embryogenesisREACTOMER-HSA-5617472

References

Pubmed IDYearTitleCitations
208526322010A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.172
208526322010A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.172
229307472012Genome-wide methylation screen in low-grade breast cancer identifies novel epigenetically altered genes as potential biomarkers for tumor diagnosis.29
194532612009High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.20
199380812009Altered transmission of HOX and apoptotic SNPs identify a potential common pathway for clubfoot.14
215015862011Homeobox D1 regulates angiogenic functions of endothelial cells via integrin β1 expression.6

Citation

Dessen P

HOXD1 (homeobox D1)

Atlas Genet Cytogenet Oncol Haematol. 2010-11-01

Online version: http://atlasgeneticsoncology.org/gene/51756/hoxd1