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HOXD10 (homeobox D10)

Identity

Alias_namesHOX4
HOX4D
homeo box D10
Other aliasHOX4E
Hox-4.4
HGNC (Hugo) HOXD10
LocusID (NCBI) 3236
Atlas_Id 52373
Location 2q31.1  [Link to chromosome band 2q31]
Location_base_pair Starts at 176981492 and ends at 176984670 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
HOXD11 (2q31.1) / HOXD10 (2q31.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HOXD10   5133
LRG (Locus Reference Genomic)LRG_246
Cards
Entrez_Gene (NCBI)HOXD10  3236  homeobox D10
AliasesHOX4; HOX4D; HOX4E; Hox-4.4
GeneCards (Weizmann)HOXD10
Ensembl hg19 (Hinxton)ENSG00000128710 [Gene_View]  chr2:176981492-176984670 [Contig_View]  HOXD10 [Vega]
Ensembl hg38 (Hinxton)ENSG00000128710 [Gene_View]  chr2:176981492-176984670 [Contig_View]  HOXD10 [Vega]
ICGC DataPortalENSG00000128710
TCGA cBioPortalHOXD10
AceView (NCBI)HOXD10
Genatlas (Paris)HOXD10
WikiGenes3236
SOURCE (Princeton)HOXD10
Genetics Home Reference (NIH)HOXD10
Genomic and cartography
GoldenPath hg19 (UCSC)HOXD10  -     chr2:176981492-176984670 +  2q31.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)HOXD10  -     2q31.1   [Description]    (hg38-Dec_2013)
EnsemblHOXD10 - 2q31.1 [CytoView hg19]  HOXD10 - 2q31.1 [CytoView hg38]
Mapping of homologs : NCBIHOXD10 [Mapview hg19]  HOXD10 [Mapview hg38]
OMIM142984   192950   
Gene and transcription
Genbank (Entrez)AA653427 AI651040 AK309451 AL526269 AW243295
RefSeq transcript (Entrez)NM_002148
RefSeq genomic (Entrez)NC_000002 NC_018913 NG_008133 NT_005403 NW_004929305
Consensus coding sequences : CCDS (NCBI)HOXD10
Cluster EST : UnigeneHs.123070 [ NCBI ]
CGAP (NCI)Hs.123070
Alternative Splicing GalleryENSG00000128710
Gene ExpressionHOXD10 [ NCBI-GEO ]   HOXD10 [ EBI - ARRAY_EXPRESS ]   HOXD10 [ SEEK ]   HOXD10 [ MEM ]
Gene Expression Viewer (FireBrowse)HOXD10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3236
GTEX Portal (Tissue expression)HOXD10
Protein : pattern, domain, 3D structure
UniProt/SwissProtP28358   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP28358  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP28358
Splice isoforms : SwissVarP28358
PhosPhoSitePlusP28358
Domaine pattern : Prosite (Expaxy)HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox_CS    Homeobox_dom    Homeobox_metazoa    Homeodomain-like   
Domain families : Pfam (Sanger)Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)HOXD10
DMDM Disease mutations3236
Blocks (Seattle)HOXD10
SuperfamilyP28358
Human Protein AtlasENSG00000128710
Peptide AtlasP28358
HPRD00867
IPIIPI00292735   
Protein Interaction databases
DIP (DOE-UCLA)P28358
IntAct (EBI)P28358
FunCoupENSG00000128710
BioGRIDHOXD10
STRING (EMBL)HOXD10
ZODIACHOXD10
Ontologies - Pathways
QuickGOP28358
Ontology : AmiGOchromatin binding  transcription factor activity, sequence-specific DNA binding  nucleus  transcription, DNA-templated  single fertilization  skeletal muscle tissue development  adult locomotory behavior  anterior/posterior pattern specification  proximal/distal pattern formation  spinal cord motor neuron cell fate specification  embryonic limb morphogenesis  forelimb morphogenesis  hindlimb morphogenesis  sequence-specific DNA binding  positive regulation of transcription from RNA polymerase II promoter  embryonic skeletal system morphogenesis  peripheral nervous system neuron development  neuromuscular process  
Ontology : EGO-EBIchromatin binding  transcription factor activity, sequence-specific DNA binding  nucleus  transcription, DNA-templated  single fertilization  skeletal muscle tissue development  adult locomotory behavior  anterior/posterior pattern specification  proximal/distal pattern formation  spinal cord motor neuron cell fate specification  embryonic limb morphogenesis  forelimb morphogenesis  hindlimb morphogenesis  sequence-specific DNA binding  positive regulation of transcription from RNA polymerase II promoter  embryonic skeletal system morphogenesis  peripheral nervous system neuron development  neuromuscular process  
Pathways : KEGGProteoglycans in cancer    MicroRNAs in cancer   
NDEx NetworkHOXD10
Atlas of Cancer Signalling NetworkHOXD10
Wikipedia pathwaysHOXD10
Orthology - Evolution
OrthoDB3236
GeneTree (enSembl)ENSG00000128710
Phylogenetic Trees/Animal Genes : TreeFamHOXD10
HOVERGENP28358
HOGENOMP28358
Homologs : HomoloGeneHOXD10
Homology/Alignments : Family Browser (UCSC)HOXD10
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHOXD10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HOXD10
dbVarHOXD10
ClinVarHOXD10
1000_GenomesHOXD10 
Exome Variant ServerHOXD10
ExAC (Exome Aggregation Consortium)HOXD10 (select the gene name)
Genetic variants : HAPMAP3236
Genomic Variants (DGV)HOXD10 [DGVbeta]
DECIPHER (Syndromes)2:176981492-176984670  ENSG00000128710
CONAN: Copy Number AnalysisHOXD10 
Mutations
ICGC Data PortalHOXD10 
TCGA Data PortalHOXD10 
Broad Tumor PortalHOXD10
OASIS PortalHOXD10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHOXD10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHOXD10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HOXD10
DgiDB (Drug Gene Interaction Database)HOXD10
DoCM (Curated mutations)HOXD10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HOXD10 (select a term)
intoGenHOXD10
Cancer3DHOXD10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM142984    192950   
Orphanet21046    21047   
MedgenHOXD10
Genetic Testing Registry HOXD10
NextProtP28358 [Medical]
TSGene3236
GENETestsHOXD10
Huge Navigator HOXD10 [HugePedia]
snp3D : Map Gene to Disease3236
BioCentury BCIQHOXD10
ClinGenHOXD10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3236
Chemical/Pharm GKB GenePA29407
Clinical trialHOXD10
Miscellaneous
canSAR (ICR)HOXD10 (select the gene name)
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHOXD10
EVEXHOXD10
GoPubMedHOXD10
iHOPHOXD10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:04:12 CEST 2017

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