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HOXD4 (homeobox D4)

Identity

Alias_namesHOX4B
HOX4
homeo box D4
Other aliasHHO.C13
HOX-5.1
Hox-4.2
HGNC (Hugo) HOXD4
LocusID (NCBI) 3233
Atlas_Id 64403
Location 2q31.1  [Link to chromosome band 2q31]
Location_base_pair Starts at 176151385 and ends at 176153221 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HOXD4   5138
Cards
Entrez_Gene (NCBI)HOXD4  3233  homeobox D4
AliasesHHO.C13; HOX-5.1; HOX4; HOX4B; 
Hox-4.2
GeneCards (Weizmann)HOXD4
Ensembl hg19 (Hinxton)ENSG00000170166 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170166 [Gene_View]  chr2:176151385-176153221 [Contig_View]  HOXD4 [Vega]
ICGC DataPortalENSG00000170166
TCGA cBioPortalHOXD4
AceView (NCBI)HOXD4
Genatlas (Paris)HOXD4
WikiGenes3233
SOURCE (Princeton)HOXD4
Genetics Home Reference (NIH)HOXD4
Genomic and cartography
GoldenPath hg38 (UCSC)HOXD4  -     chr2:176151385-176153221 +  2q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HOXD4  -     2q31.1   [Description]    (hg19-Feb_2009)
EnsemblHOXD4 - 2q31.1 [CytoView hg19]  HOXD4 - 2q31.1 [CytoView hg38]
Mapping of homologs : NCBIHOXD4 [Mapview hg19]  HOXD4 [Mapview hg38]
OMIM142981   
Gene and transcription
Genbank (Entrez)AK311735 AK313885 BC016763 BC074797 X04706
RefSeq transcript (Entrez)NM_014621
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HOXD4
Cluster EST : UnigeneHs.591609 [ NCBI ]
CGAP (NCI)Hs.591609
Alternative Splicing GalleryENSG00000170166
Gene ExpressionHOXD4 [ NCBI-GEO ]   HOXD4 [ EBI - ARRAY_EXPRESS ]   HOXD4 [ SEEK ]   HOXD4 [ MEM ]
Gene Expression Viewer (FireBrowse)HOXD4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3233
GTEX Portal (Tissue expression)HOXD4
Human Protein AtlasENSG00000170166-HOXD4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09016   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP09016  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP09016
Splice isoforms : SwissVarP09016
PhosPhoSitePlusP09016
Domaine pattern : Prosite (Expaxy)ANTENNAPEDIA (PS00032)    HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (EBI)Homeobox-like    Homeobox_antennapedia    Homeobox_Antennapedia_CS    Homeobox_CS    Homeobox_dom    Homeobox_metazoa   
Domain families : Pfam (Sanger)Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
Conserved Domain (NCBI)HOXD4
DMDM Disease mutations3233
Blocks (Seattle)HOXD4
SuperfamilyP09016
Human Protein Atlas [tissue]ENSG00000170166-HOXD4 [tissue]
Peptide AtlasP09016
HPRD00864
IPIIPI00012390   
Protein Interaction databases
DIP (DOE-UCLA)P09016
IntAct (EBI)P09016
FunCoupENSG00000170166
BioGRIDHOXD4
STRING (EMBL)HOXD4
ZODIACHOXD4
Ontologies - Pathways
QuickGOP09016
Ontology : AmiGORNA polymerase II regulatory region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding  nucleus  nucleoplasm  transcription from RNA polymerase II promoter  multicellular organism development  anterior/posterior pattern specification  cell junction  positive regulation of transcription from RNA polymerase II promoter  embryonic skeletal system morphogenesis  stem cell differentiation  
Ontology : EGO-EBIRNA polymerase II regulatory region sequence-specific DNA binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding  transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding  nucleus  nucleoplasm  transcription from RNA polymerase II promoter  multicellular organism development  anterior/posterior pattern specification  cell junction  positive regulation of transcription from RNA polymerase II promoter  embryonic skeletal system morphogenesis  stem cell differentiation  
NDEx NetworkHOXD4
Atlas of Cancer Signalling NetworkHOXD4
Wikipedia pathwaysHOXD4
Orthology - Evolution
OrthoDB3233
GeneTree (enSembl)ENSG00000170166
Phylogenetic Trees/Animal Genes : TreeFamHOXD4
HOVERGENP09016
HOGENOMP09016
Homologs : HomoloGeneHOXD4
Homology/Alignments : Family Browser (UCSC)HOXD4
Gene fusions - Rearrangements
Tumor Fusion PortalHOXD4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHOXD4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HOXD4
dbVarHOXD4
ClinVarHOXD4
1000_GenomesHOXD4 
Exome Variant ServerHOXD4
ExAC (Exome Aggregation Consortium)ENSG00000170166
GNOMAD BrowserENSG00000170166
Genetic variants : HAPMAP3233
Genomic Variants (DGV)HOXD4 [DGVbeta]
DECIPHERHOXD4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHOXD4 
Mutations
ICGC Data PortalHOXD4 
TCGA Data PortalHOXD4 
Broad Tumor PortalHOXD4
OASIS PortalHOXD4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHOXD4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHOXD4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HOXD4
DgiDB (Drug Gene Interaction Database)HOXD4
DoCM (Curated mutations)HOXD4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HOXD4 (select a term)
intoGenHOXD4
Cancer3DHOXD4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM142981   
Orphanet
DisGeNETHOXD4
MedgenHOXD4
Genetic Testing Registry HOXD4
NextProtP09016 [Medical]
TSGene3233
GENETestsHOXD4
Target ValidationHOXD4
Huge Navigator HOXD4 [HugePedia]
snp3D : Map Gene to Disease3233
BioCentury BCIQHOXD4
ClinGenHOXD4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3233
Chemical/Pharm GKB GenePA29412
Clinical trialHOXD4
Miscellaneous
canSAR (ICR)HOXD4 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHOXD4
EVEXHOXD4
GoPubMedHOXD4
iHOPHOXD4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:04:41 CET 2017

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